Genome ID：GCA_009716755.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	33	38.64

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
CMFOOCNG_7	138806	140023	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
CMFOOCNG_7	140143	141606	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	99.93	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
CMFOOCNG_7	138806	140020	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
CMFOOCNG_7	140143	141603	msr(D)	ABC-F type ribosomal protection protein Msr(D)	BLASTX	99.79	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
CMFOOCNG_9	126436	127404	STER_RS07090	0.0	Capsule	Immune modulation	98.86	100.00	WP_011681443
CMFOOCNG_9	124215	125468	STER_RS07100	0.0	Capsule	Immune modulation	96.81	99.52	WP_011681445
CMFOOCNG_7	61925	63385	STER_RS05320	0.0	Capsule	Immune modulation	96.72	100.00	WP_011681177
CMFOOCNG_7	61925	63385	STU_RS14650	0.0	Capsule	Immune modulation	96.37	100.21	WP_011226049
CMFOOCNG_9	127406	128121	STER_RS07085	0.0	Capsule	Immune modulation	95.95	99.86	WP_011681442
CMFOOCNG_7	61925	63385	STR_RS05265	0.0	Capsule	Immune modulation	95.69	100.21	WP_041827043
CMFOOCNG_9	123245	124096	rfbD	0.0	Capsule	Immune modulation	94.72	100.00	WP_014621820
CMFOOCNG_7	65625	66992	STU_RS14630	0.0	Capsule	Immune modulation	94.59	100.00	WP_011226045
CMFOOCNG_7	65625	66990	STER_RS05300	0.0	Capsule	Immune modulation	94.29	99.85	WP_011681173
CMFOOCNG_9	128467	129237	STER_RS07075	0.0	Capsule	Immune modulation	94.16	99.23	WP_011681440
CMFOOCNG_7	64828	65568	STER_RS05305	0.0	Capsule	Immune modulation	93.93	100.00	WP_011681174
CMFOOCNG_7	63386	64117	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
CMFOOCNG_7	63386	64117	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
CMFOOCNG_7	64828	65568	STU_RS14635	0.0	Capsule	Immune modulation	93.25	100.00	WP_011226046
CMFOOCNG_7	63386	64117	STR_RS05260	0.0	Capsule	Immune modulation	93.03	100.00	WP_011227248
CMFOOCNG_7	64828	65563	STR_RS05250	0.0	Capsule	Immune modulation	92.66	98.13	WP_011227246
CMFOOCNG_6	75362	75955	STR_RS05880	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
CMFOOCNG_6	75362	75955	STER_RS06030	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
CMFOOCNG_6	75362	75955	STU_RS15260	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
CMFOOCNG_6	75955	76824	rfbA	0.0	Capsule	Immune modulation	90.92	100.00	WP_011681286
CMFOOCNG_14	22307	23146	cbpD	0.0	Autolysin	Exoenzyme	90.62	99.88	WP_011226733
CMFOOCNG_7	186153	187811	fbp54	0.0	FBPs	Adherence	90.24	99.94	WP_011227179
CMFOOCNG_11	191309	192319	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.55	99.80	WP_002986042
CMFOOCNG_6	237693	238996	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
CMFOOCNG_7	64126	64818	STR_RS05255	0.0	Capsule	Immune modulation	87.46	99.86	WP_011227247
CMFOOCNG_7	64126	64818	STU_RS14640	0.0	Capsule	Immune modulation	87.46	99.86	WP_011226047
CMFOOCNG_7	64126	64818	STER_RS05310	0.0	Capsule	Immune modulation	87.18	99.86	WP_011681175
CMFOOCNG_1	42413	43174	srtA	0.0	Sortase A	Exoenzyme	84.53	99.87	-
CMFOOCNG_6	74045	75091	rfbB	0.0	Capsule	Immune modulation	84.06	99.90	WP_002263087
CMFOOCNG_8	214084	215367	tig/ropA	0.0	Trigger factor	Stress survival	81.01	99.53	WP_000107753
CMFOOCNG_7	76066	76649	SPD_RS01775	1.94e-152	Capsule	Immune modulation	83.59	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
CMFOOCNG_7	319865	318792	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
CMFOOCNG_1	39725	38751	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.00	99.09	AAK75326
CMFOOCNG_11	63909	66215	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
CMFOOCNG_12	111682	113163	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
CMFOOCNG_6	329837	328869	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
CMFOOCNG_7	300806	298560	metE	0.0	methionine biosynthesis enzymes	92.52	100.00	AAK74738
CMFOOCNG_14	3564	4535	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
CMFOOCNG_6	102209	100479	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
CMFOOCNG_9	109807	111795	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
CMFOOCNG_9	81203	82354	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
CMFOOCNG_10	189210	187732	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
CMFOOCNG_6	238996	237695	Eno	0.0	enolase	86.44	99.77	ABP90468
CMFOOCNG_10	173890	171998	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.42	98.90	ABP91129
CMFOOCNG_7	295641	297350	PGM	0.0	phosphoglucomutase	84.94	99.65	ACH87041
CMFOOCNG_14	44516	45607	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
CMFOOCNG_10	28786	29796	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
CMFOOCNG_7	170601	171962	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
CMFOOCNG_6	253402	252512	bglB	3.07e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
CMFOOCNG_7	256342	257304	SP_0676	1.57e-169	transcription facot	80.69	99.69	AAK74821
CMFOOCNG_7	298373	297516	metF	2.61e-168	methionine biosynthesis enzymes	87.76	99.31	AAK74739
CMFOOCNG_12	45317	44646	rr01	3.36e-127	response regulator	84.82	99.56	CAB54566
CMFOOCNG_7	14737	15441	covR	5.24e-126	responder protein	85.11	100.00	AAK71319
CMFOOCNG_7	291673	291002	ciaR	2.22e-125	two component system response regulator	86.16	99.12	AIK75708
CMFOOCNG_7	291673	291011	CiaR	3.16e-124	two-component response regulator	87.78	98.66	AAK74935
CMFOOCNG_8	55419	54733	CovR	4.76e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
CMFOOCNG_7	14737	15441	walR	9.62e-120	DNA-binding response regulator	81.70	100.00	ANC99504
CMFOOCNG_14	45780	46175	SpxA2	4.57e-76	transcriptional regulator	91.67	100.00	ERL21461
CMFOOCNG_7	159137	158736	SpxA1	6.28e-70	transcriptional regulator	82.84	100.00	ERL19273
CMFOOCNG_13	5999	5595	GrpE	9.90e-68	protein grpE	82.96	78.82	ABP89267
CMFOOCNG_8	32209	31922	spr0479	5.77e-48	essential gene	85.42	98.97	AAK99283
CMFOOCNG_6	387099	386845	spr1327	2.44e-44	essential gene	92.94	100.00	AAL00131
CMFOOCNG_10	143016	143279	spr0175	1.11e-42	pathogenitcity related	85.23	100.00	AAK98979
CMFOOCNG_10	143842	144108	spr0177	1.55e-41	essential gene	83.15	88.12	AAK98981
CMFOOCNG_8	213917	213426	RopE (M5005_Spy_1611)	1.05e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
CMFOOCNG_11	63909	66209	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
CMFOOCNG_10	65200	64181	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451