Genome ID：GCA_009716945.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	20	33	38.59

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NHIMFEAK_3	35604	36335	STR_RS05260	0.0	Capsule	Immune modulation	94.40	100.00	WP_011227248
NHIMFEAK_11	154249	155100	rfbD	0.0	Capsule	Immune modulation	94.25	100.00	WP_014621820
NHIMFEAK_3	35604	36335	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
NHIMFEAK_3	35604	36335	STER_RS05315	0.0	Capsule	Immune modulation	93.44	100.00	WP_011681176
NHIMFEAK_11	157362	158171	STU_RS16245	0.0	Capsule	Immune modulation	92.85	99.88	WP_002948020
NHIMFEAK_11	160428	162184	STU_RS16230	0.0	Capsule	Immune modulation	92.60	98.43	WP_011226325
NHIMFEAK_11	158171	159376	STU_RS16240	0.0	Capsule	Immune modulation	92.37	100.00	WP_011226326
NHIMFEAK_11	156422	157378	STU_RS16250	0.0	Capsule	Immune modulation	91.85	100.00	WP_011226328
NHIMFEAK_11	155277	156425	STU_RS16255	0.0	Capsule	Immune modulation	91.57	99.83	WP_041828290
NHIMFEAK_33	59976	61634	fbp54	0.0	FBPs	Adherence	91.14	99.94	WP_011227179
NHIMFEAK_3	34143	35603	STER_RS05320	0.0	Capsule	Immune modulation	91.13	99.86	WP_011681177
NHIMFEAK_37	32312	32905	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
NHIMFEAK_11	159397	160431	STU_RS16235	0.0	Capsule	Immune modulation	91.00	99.15	WP_002948022
NHIMFEAK_37	32312	32905	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
NHIMFEAK_37	32312	32905	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
NHIMFEAK_3	34143	35603	STU_RS14650	0.0	Capsule	Immune modulation	90.51	100.00	WP_011226049
NHIMFEAK_3	36344	37036	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
NHIMFEAK_3	34143	35603	STR_RS05265	0.0	Capsule	Immune modulation	89.83	100.00	WP_041827043
NHIMFEAK_3	36344	37036	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
NHIMFEAK_3	36344	37036	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
NHIMFEAK_41	40495	41798	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
NHIMFEAK_11	77211	78050	cbpD	0.0	Autolysin	Exoenzyme	87.87	99.88	WP_011226733
NHIMFEAK_38	14381	15394	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
NHIMFEAK_33	208954	209715	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
NHIMFEAK_37	30996	32042	rfbB	0.0	Capsule	Immune modulation	83.49	99.90	WP_002263087
NHIMFEAK_22	219225	220508	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
NHIMFEAK_37	32905	33774	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
NHIMFEAK_3	37046	37716	STU_RS14635	6.33e-150	Capsule	Immune modulation	81.13	90.28	WP_011226046
NHIMFEAK_3	37046	37716	STER_RS05305	2.95e-148	Capsule	Immune modulation	80.98	90.28	WP_011681174
NHIMFEAK_3	37046	37716	STR_RS05250	2.99e-138	Capsule	Immune modulation	80.09	89.20	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NHIMFEAK_33	212404	213387	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
NHIMFEAK_33	200818	199745	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
NHIMFEAK_38	147584	145278	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.28	99.22	AAK74619
NHIMFEAK_40	121224	122705	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
NHIMFEAK_33	181757	179511	metE	0.0	methionine biosynthesis enzymes	92.66	100.00	AAK74738
NHIMFEAK_42	59865	60833	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
NHIMFEAK_10	4392	5363	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
NHIMFEAK_37	59147	57417	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	90.12	100.00	AAK34199
NHIMFEAK_11	142073	144061	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
NHIMFEAK_2	29775	30926	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
NHIMFEAK_12	29286	27808	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
NHIMFEAK_41	41798	40497	Eno	0.0	enolase	86.44	99.77	ABP90468
NHIMFEAK_12	13940	12048	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
NHIMFEAK_33	176589	178298	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
NHIMFEAK_10	38830	39921	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
NHIMFEAK_1	19508	20518	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
NHIMFEAK_33	46460	47821	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
NHIMFEAK_41	56206	55316	bglB	8.13e-178	putative phospho--glucosidase	87.20	99.66	AAK33487
NHIMFEAK_33	135778	136728	SP_0676	3.25e-170	transcription facot	81.39	98.45	AAK74821
NHIMFEAK_33	179321	178464	metF	9.56e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
NHIMFEAK_3	1845	2549	covR	2.20e-127	responder protein	85.53	100.00	AAK71319
NHIMFEAK_40	54677	54006	rr01	3.49e-127	response regulator	84.82	99.56	CAB54566
NHIMFEAK_33	172619	171948	ciaR	2.12e-125	two component system response regulator	86.16	99.12	AIK75708
NHIMFEAK_33	172619	171951	CiaR	3.91e-125	two-component response regulator	87.44	99.55	AAK74935
NHIMFEAK_3	1845	2549	walR	5.01e-121	DNA-binding response regulator	82.13	100.00	ANC99504
NHIMFEAK_22	53840	53154	CovR	4.84e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
NHIMFEAK_10	40094	40489	SpxA2	4.01e-76	transcriptional regulator	91.67	100.00	ERL21461
NHIMFEAK_33	35003	34602	SpxA1	1.41e-69	transcriptional regulator	82.09	100.00	ERL19273
NHIMFEAK_6	6826	6413	GrpE	2.33e-68	protein grpE	81.88	80.59	ABP89267
NHIMFEAK_22	30631	30344	spr0479	5.86e-48	essential gene	85.42	98.97	AAK99283
NHIMFEAK_42	20954	21208	spr1327	2.62e-44	essential gene	90.59	100.00	AAL00131
NHIMFEAK_13	1312	1049	spr0175	1.54e-43	pathogenitcity related	85.23	100.00	AAK98979
NHIMFEAK_13	487	221	spr0177	3.41e-42	essential gene	83.15	88.12	AAK98981
NHIMFEAK_22	219058	218567	RopE (M5005_Spy_1611)	1.07e-72	probable DNA-directed RNA polymerase subunit delta	83.54	85.86	AAK34603
NHIMFEAK_38	147584	145284	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.97	98.08	MYN69560
NHIMFEAK_18	9485	10504	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451
NHIMFEAK_33	75462	74923	pnuC	2.90e-94	NAD salvage pathway importer	83.89	66.91	AAK75931