Genome ID：GCA_009717045.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	33	39.71

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
FOFKJANH_4	236081	237298	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
FOFKJANH_4	234498	235961	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
FOFKJANH_4	236084	237298	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
FOFKJANH_4	234501	235961	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
FOFKJANH_3	998014	999474	STU_RS14650	0.0	Capsule	Immune modulation	96.92	100.21	WP_011226049
FOFKJANH_3	998014	999474	STER_RS05320	0.0	Capsule	Immune modulation	96.85	100.00	WP_011681177
FOFKJANH_3	998014	999474	STR_RS05265	0.0	Capsule	Immune modulation	96.03	100.21	WP_041827043
FOFKJANH_3	354937	355746	STU_RS16245	0.0	Capsule	Immune modulation	95.31	100.00	WP_002948020
FOFKJANH_3	994409	995774	STER_RS05300	0.0	Capsule	Immune modulation	95.09	99.85	WP_011681173
FOFKJANH_3	346948	347799	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
FOFKJANH_3	995831	996571	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
FOFKJANH_3	994407	995774	STU_RS14630	0.0	Capsule	Immune modulation	94.59	100.00	WP_011226045
FOFKJANH_3	995831	996571	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
FOFKJANH_5	2648	3931	tig/ropA	0.0	Trigger factor	Stress survival	94.08	100.00	WP_011225339
FOFKJANH_3	995836	996571	STR_RS05250	0.0	Capsule	Immune modulation	93.89	98.13	WP_011227246
FOFKJANH_3	997282	998013	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
FOFKJANH_3	997282	998013	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
FOFKJANH_3	348900	350171	STU_RS16265	0.0	Capsule	Immune modulation	93.71	99.76	WP_011226331
FOFKJANH_3	355746	356951	STU_RS16240	0.0	Capsule	Immune modulation	93.53	100.00	WP_011226326
FOFKJANH_3	997282	998013	STR_RS05260	0.0	Capsule	Immune modulation	93.17	100.00	WP_011227248
FOFKJANH_3	358002	359786	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
FOFKJANH_3	352852	354000	STU_RS16255	0.0	Capsule	Immune modulation	92.17	100.00	WP_041828290
FOFKJANH_4	80558	81151	STR_RS05880	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
FOFKJANH_4	80558	81151	STER_RS06030	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
FOFKJANH_4	80558	81151	STU_RS15260	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
FOFKJANH_3	356971	358005	STU_RS16235	0.0	Capsule	Immune modulation	91.39	99.05	WP_002948022
FOFKJANH_3	353997	354953	STU_RS16250	0.0	Capsule	Immune modulation	91.33	100.00	WP_011226328
FOFKJANH_4	81151	82020	rfbA	0.0	Capsule	Immune modulation	91.03	100.00	WP_011681286
FOFKJANH_3	888232	889890	fbp54	0.0	FBPs	Adherence	90.36	99.94	WP_011227179
FOFKJANH_3	14388	15398	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
FOFKJANH_3	996581	997273	STR_RS05255	0.0	Capsule	Immune modulation	88.47	99.86	WP_011227247
FOFKJANH_3	996581	997273	STU_RS14640	0.0	Capsule	Immune modulation	88.47	99.86	WP_011226047
FOFKJANH_4	261482	262785	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
FOFKJANH_4	440743	441648	cbpD	0.0	Autolysin	Exoenzyme	88.41	93.50	WP_082302295
FOFKJANH_3	996581	997273	STER_RS05310	0.0	Capsule	Immune modulation	88.18	99.86	WP_011681175
FOFKJANH_3	732776	733537	srtA	0.0	Sortase A	Exoenzyme	84.03	99.74	-
FOFKJANH_4	79309	80355	rfbB	0.0	Capsule	Immune modulation	80.42	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
FOFKJANH_3	730086	729112	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.92	99.09	AAK75326
FOFKJANH_3	741667	742740	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
FOFKJANH_3	146384	144078	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
FOFKJANH_4	352582	351614	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
FOFKJANH_3	574741	573260	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
FOFKJANH_3	769722	771968	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
FOFKJANH_8	35936	34965	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
FOFKJANH_3	296920	298068	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	90.08	99.48	AAL00050
FOFKJANH_4	107405	105675	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
FOFKJANH_3	333552	335540	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
FOFKJANH_6	163545	162067	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
FOFKJANH_4	262785	261484	Eno	0.0	enolase	86.44	99.77	ABP90468
FOFKJANH_6	148222	146330	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
FOFKJANH_3	774887	773178	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
FOFKJANH_8	2042	951	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
FOFKJANH_6	28753	29763	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
FOFKJANH_3	903411	902050	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
FOFKJANH_4	277195	276305	bglB	2.24e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
FOFKJANH_3	815746	814796	SP_0676	2.81e-169	transcription facot	81.39	98.45	AAK74821
FOFKJANH_3	772155	773012	metF	2.30e-167	methionine biosynthesis enzymes	87.06	99.31	AAK74739
FOFKJANH_3	646856	647527	rr01	2.00e-126	response regulator	84.82	99.56	CAB54566
FOFKJANH_3	1045040	1044336	covR	1.66e-125	responder protein	85.11	100.00	AAK71319
FOFKJANH_3	778855	779526	ciaR	4.67e-124	two component system response regulator	85.71	99.12	AIK75708
FOFKJANH_3	778855	779523	CiaR	5.81e-124	two-component response regulator	87.00	99.55	AAK74935
FOFKJANH_5	162188	162874	CovR	4.80e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
FOFKJANH_3	1045040	1044336	walR	3.04e-119	DNA-binding response regulator	81.70	100.00	ANC99504
FOFKJANH_8	777	382	SpxA2	3.99e-76	transcriptional regulator	91.67	100.00	ERL21461
FOFKJANH_3	914877	915278	SpxA1	1.16e-68	transcriptional regulator	82.09	100.00	ERL19273
FOFKJANH_7	6355	5942	GrpE	9.69e-68	protein grpE	81.16	80.59	ABP89267
FOFKJANH_5	185967	186254	spr0479	5.81e-48	essential gene	85.42	98.97	AAK99283
FOFKJANH_4	388742	388488	spr1327	2.34e-44	essential gene	92.94	100.00	AAL00131
FOFKJANH_6	117225	117488	spr0175	9.79e-43	pathogenitcity related	85.23	100.00	AAK98979
FOFKJANH_6	118051	118317	spr0177	1.36e-41	essential gene	83.15	88.12	AAK98981
FOFKJANH_5	4098	4589	RopE (M5005_Spy_1611)	1.06e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
FOFKJANH_3	146384	144084	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
FOFKJANH_6	65475	64456	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.77	100.00	ABJ55451