Genome ID：GCA_009717115.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	33	39.71

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
KINKAGAG_5	235660	236877	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
KINKAGAG_5	234077	235540	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
KINKAGAG_5	235663	236877	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
KINKAGAG_5	234080	235540	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
KINKAGAG_6	47450	48910	STU_RS14650	0.0	Capsule	Immune modulation	96.92	100.21	WP_011226049
KINKAGAG_6	47450	48910	STER_RS05320	0.0	Capsule	Immune modulation	96.85	100.00	WP_011681177
KINKAGAG_6	47450	48910	STR_RS05265	0.0	Capsule	Immune modulation	96.03	100.21	WP_041827043
KINKAGAG_10	75797	76606	STU_RS16245	0.0	Capsule	Immune modulation	95.31	100.00	WP_002948020
KINKAGAG_6	51150	52515	STER_RS05300	0.0	Capsule	Immune modulation	95.09	99.85	WP_011681173
KINKAGAG_10	83744	84595	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
KINKAGAG_6	50353	51093	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
KINKAGAG_6	51150	52517	STU_RS14630	0.0	Capsule	Immune modulation	94.59	100.00	WP_011226045
KINKAGAG_6	50353	51093	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
KINKAGAG_8	2648	3931	tig/ropA	0.0	Trigger factor	Stress survival	94.08	100.00	WP_011225339
KINKAGAG_6	50353	51088	STR_RS05250	0.0	Capsule	Immune modulation	93.89	98.13	WP_011227246
KINKAGAG_6	48911	49642	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
KINKAGAG_6	48911	49642	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
KINKAGAG_10	81372	82643	STU_RS16265	0.0	Capsule	Immune modulation	93.71	99.76	WP_011226331
KINKAGAG_10	74592	75797	STU_RS16240	0.0	Capsule	Immune modulation	93.53	100.00	WP_011226326
KINKAGAG_6	48911	49642	STR_RS05260	0.0	Capsule	Immune modulation	93.17	100.00	WP_011227248
KINKAGAG_10	71757	73541	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
KINKAGAG_10	77543	78691	STU_RS16255	0.0	Capsule	Immune modulation	92.17	100.00	WP_041828290
KINKAGAG_5	80137	80730	STR_RS05880	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
KINKAGAG_5	80137	80730	STER_RS06030	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
KINKAGAG_5	80137	80730	STU_RS15260	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
KINKAGAG_10	73538	74572	STU_RS16235	0.0	Capsule	Immune modulation	91.39	99.05	WP_002948022
KINKAGAG_10	76590	77546	STU_RS16250	0.0	Capsule	Immune modulation	91.33	100.00	WP_011226328
KINKAGAG_5	80730	81599	rfbA	0.0	Capsule	Immune modulation	91.03	100.00	WP_011681286
KINKAGAG_12	20712	21551	cbpD	0.0	Autolysin	Exoenzyme	90.95	100.00	WP_011226733
KINKAGAG_6	157034	158692	fbp54	0.0	FBPs	Adherence	90.36	99.94	WP_011227179
KINKAGAG_7	14388	15398	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
KINKAGAG_6	49651	50343	STR_RS05255	0.0	Capsule	Immune modulation	88.47	99.86	WP_011227247
KINKAGAG_6	49651	50343	STU_RS14640	0.0	Capsule	Immune modulation	88.47	99.86	WP_011226047
KINKAGAG_5	261061	262364	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
KINKAGAG_6	49651	50343	STER_RS05310	0.0	Capsule	Immune modulation	88.18	99.86	WP_011681175
KINKAGAG_6	313177	313938	srtA	0.0	Sortase A	Exoenzyme	84.03	99.74	-
KINKAGAG_5	78888	79934	rfbB	0.0	Capsule	Immune modulation	80.42	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
KINKAGAG_6	316628	317602	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.92	99.09	AAK75326
KINKAGAG_6	305047	303974	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
KINKAGAG_7	146384	144078	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
KINKAGAG_5	352161	351193	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
KINKAGAG_6	471973	473454	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
KINKAGAG_6	276992	274746	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
KINKAGAG_12	35936	34965	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
KINKAGAG_7	296920	298068	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	90.08	99.48	AAL00050
KINKAGAG_5	106984	105254	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
KINKAGAG_10	97991	96003	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
KINKAGAG_9	163546	162068	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
KINKAGAG_5	262364	261063	Eno	0.0	enolase	86.44	99.77	ABP90468
KINKAGAG_9	148223	146331	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
KINKAGAG_6	271827	273536	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
KINKAGAG_12	2042	951	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
KINKAGAG_9	28754	29764	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
KINKAGAG_6	143513	144874	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
KINKAGAG_5	276774	275884	bglB	6.78e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
KINKAGAG_6	231178	232128	SP_0676	1.41e-169	transcription facot	81.39	98.45	AAK74821
KINKAGAG_6	274559	273702	metF	1.15e-167	methionine biosynthesis enzymes	87.06	99.31	AAK74739
KINKAGAG_6	399858	399187	rr01	1.00e-126	response regulator	84.82	99.56	CAB54566
KINKAGAG_6	1884	2588	covR	8.29e-126	responder protein	85.11	100.00	AAK71319
KINKAGAG_6	267859	267188	ciaR	2.34e-124	two component system response regulator	85.71	99.12	AIK75708
KINKAGAG_6	267859	267191	CiaR	2.90e-124	two-component response regulator	87.00	99.55	AAK74935
KINKAGAG_8	162188	162874	CovR	4.80e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
KINKAGAG_6	1884	2588	walR	1.52e-119	DNA-binding response regulator	81.70	100.00	ANC99504
KINKAGAG_12	777	382	SpxA2	3.95e-76	transcriptional regulator	91.67	100.00	ERL21461
KINKAGAG_6	132047	131646	SpxA1	5.79e-69	transcriptional regulator	82.09	100.00	ERL19273
KINKAGAG_11	6355	5942	GrpE	9.69e-68	protein grpE	81.16	80.59	ABP89267
KINKAGAG_8	185967	186254	spr0479	5.81e-48	essential gene	85.42	98.97	AAK99283
KINKAGAG_5	388563	388309	spr1327	2.48e-44	essential gene	92.94	100.00	AAL00131
KINKAGAG_9	117226	117489	spr0175	9.79e-43	pathogenitcity related	85.23	100.00	AAK98979
KINKAGAG_9	118052	118318	spr0177	1.36e-41	essential gene	83.15	88.12	AAK98981
KINKAGAG_8	4098	4589	RopE (M5005_Spy_1611)	1.06e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
KINKAGAG_7	146384	144084	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
KINKAGAG_9	65476	64457	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.77	100.00	ABJ55451