Genome ID：GCA_009717145.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	15	34	37.22

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
JFAFKPKF_9	11389	12606	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
JFAFKPKF_9	9806	11269	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
JFAFKPKF_9	11392	12606	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
JFAFKPKF_9	9809	11269	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
JFAFKPKF_22	80363	81214	rfbD	0.0	Capsule	Immune modulation	94.95	100.00	WP_014621820
JFAFKPKF_3	46807	48267	STU_RS14650	0.0	Capsule	Immune modulation	93.98	100.14	WP_011226049
JFAFKPKF_3	46807	48267	STER_RS05320	0.0	Capsule	Immune modulation	93.98	100.00	WP_011681177
JFAFKPKF_3	46807	48267	STR_RS05265	0.0	Capsule	Immune modulation	93.22	100.14	WP_041827043
JFAFKPKF_3	43199	44566	STU_RS14630	0.0	Capsule	Immune modulation	93.13	100.00	WP_011226045
JFAFKPKF_3	43201	44566	STER_RS05300	0.0	Capsule	Immune modulation	92.97	99.85	WP_011681173
JFAFKPKF_11	82622	83215	STR_RS05880	0.0	Capsule	Immune modulation	92.42	100.00	WP_011226149
JFAFKPKF_11	82622	83215	STER_RS06030	0.0	Capsule	Immune modulation	92.26	100.00	WP_011226149
JFAFKPKF_11	82622	83215	STU_RS15260	0.0	Capsule	Immune modulation	92.26	100.00	WP_011226149
JFAFKPKF_3	46075	46806	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
JFAFKPKF_11	83215	84084	rfbA	0.0	Capsule	Immune modulation	91.61	100.00	WP_011681286
JFAFKPKF_3	46075	46806	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
JFAFKPKF_3	46075	46806	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
JFAFKPKF_3	44624	45364	STER_RS05305	0.0	Capsule	Immune modulation	90.84	99.87	WP_011681174
JFAFKPKF_33	49600	51254	fbp54	0.0	FBPs	Adherence	90.52	99.70	WP_011227179
JFAFKPKF_3	44624	45364	STU_RS14635	0.0	Capsule	Immune modulation	89.89	99.87	WP_011226046
JFAFKPKF_3	44629	45364	STR_RS05250	0.0	Capsule	Immune modulation	89.55	98.00	WP_011227246
JFAFKPKF_11	244891	246194	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
JFAFKPKF_11	425575	426480	cbpD	0.0	Autolysin	Exoenzyme	88.08	93.50	WP_082302295
JFAFKPKF_13	5867	6877	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.36	99.80	WP_002986042
JFAFKPKF_3	45374	46066	STU_RS14640	0.0	Capsule	Immune modulation	85.45	99.86	WP_011226047
JFAFKPKF_3	45374	46066	STR_RS05255	0.0	Capsule	Immune modulation	85.16	99.86	WP_011227247
JFAFKPKF_3	45374	46066	STER_RS05310	0.0	Capsule	Immune modulation	84.87	99.86	WP_011681175
JFAFKPKF_11	81373	82419	rfbB	0.0	Capsule	Immune modulation	84.54	99.90	WP_002263087
JFAFKPKF_34	33239	34000	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
JFAFKPKF_7	1900	3183	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
JFAFKPKF_34	30550	29567	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
JFAFKPKF_34	42138	43211	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
JFAFKPKF_31	107714	110020	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.54	99.22	AAK74619
JFAFKPKF_34	61195	63441	metE	0.0	methionine biosynthesis enzymes	93.19	100.00	AAK74738
JFAFKPKF_32	37773	36292	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
JFAFKPKF_11	336670	335702	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
JFAFKPKF_8	4326	5297	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
JFAFKPKF_6	19018	12470	PrtA	0.0	serine protease	90.35	101.73	ABJ55268
JFAFKPKF_11	109466	107736	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	90.12	100.00	AAK34199
JFAFKPKF_22	66631	68619	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
JFAFKPKF_22	38225	39376	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
JFAFKPKF_4	25875	27353	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
JFAFKPKF_11	246194	244893	Eno	0.0	enolase	86.44	99.77	ABP90468
JFAFKPKF_4	41223	43115	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.42	98.90	ABP91129
JFAFKPKF_34	66363	64654	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
JFAFKPKF_8	38211	39302	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
JFAFKPKF_36	28510	29520	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
JFAFKPKF_33	67103	65742	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
JFAFKPKF_11	260602	259712	bglB	6.49e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
JFAFKPKF_34	63631	64488	metF	1.98e-170	methionine biosynthesis enzymes	88.11	99.31	AAK74739
JFAFKPKF_34	106375	105413	SP_0676	3.76e-170	transcription facot	80.69	99.69	AAK74821
JFAFKPKF_14	439	1143	covR	9.42e-128	responder protein	85.53	100.00	AAK71319
JFAFKPKF_6	56201	55530	rr01	1.43e-127	response regulator	84.82	99.56	CAB54566
JFAFKPKF_34	71030	71701	ciaR	1.73e-124	two component system response regulator	85.71	99.12	AIK75708
JFAFKPKF_34	71030	71698	CiaR	4.88e-124	two-component response regulator	86.55	99.55	AAK74935
JFAFKPKF_14	439	1143	walR	2.14e-121	DNA-binding response regulator	82.13	100.00	ANC99504
JFAFKPKF_35	55414	54728	CovR	1.94e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
JFAFKPKF_8	39476	39871	SpxA2	3.95e-76	transcriptional regulator	91.67	100.00	ERL21461
JFAFKPKF_33	78577	78978	SpxA1	1.79e-70	transcriptional regulator	82.84	100.00	ERL19273
JFAFKPKF_2	5975	5562	GrpE	5.67e-68	protein grpE	81.88	80.59	ABP89267
JFAFKPKF_35	32197	31910	spr0479	1.88e-48	essential gene	85.42	98.97	AAK99283
JFAFKPKF_11	373284	373030	spr1327	2.37e-44	essential gene	92.94	100.00	AAL00131
JFAFKPKF_4	84907	84644	spr0175	6.64e-43	pathogenitcity related	85.23	100.00	AAK98979
JFAFKPKF_4	84081	83815	spr0177	9.26e-42	essential gene	83.15	88.12	AAK98981
JFAFKPKF_7	3350	3841	RopE (M5005_Spy_1611)	2.35e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
JFAFKPKF_31	107714	110014	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
JFAFKPKF_36	103423	102404	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451