Genome ID：GCA_009717165.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	33	39.71

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
IHHHGOGC_10	201452	202669	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
IHHHGOGC_10	202789	204252	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
IHHHGOGC_10	201452	202666	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
IHHHGOGC_10	202789	204249	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
IHHHGOGC_17	48612	50072	STU_RS14650	0.0	Capsule	Immune modulation	96.92	100.21	WP_011226049
IHHHGOGC_17	48612	50072	STER_RS05320	0.0	Capsule	Immune modulation	96.85	100.00	WP_011681177
IHHHGOGC_17	48612	50072	STR_RS05265	0.0	Capsule	Immune modulation	96.03	100.21	WP_041827043
IHHHGOGC_13	355190	355999	STU_RS16245	0.0	Capsule	Immune modulation	95.31	100.00	WP_002948020
IHHHGOGC_17	45007	46372	STER_RS05300	0.0	Capsule	Immune modulation	95.09	99.85	WP_011681173
IHHHGOGC_13	347201	348052	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
IHHHGOGC_17	46429	47169	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
IHHHGOGC_17	45005	46372	STU_RS14630	0.0	Capsule	Immune modulation	94.59	100.00	WP_011226045
IHHHGOGC_17	46429	47169	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
IHHHGOGC_14	2648	3931	tig/ropA	0.0	Trigger factor	Stress survival	94.08	100.00	WP_011225339
IHHHGOGC_17	46434	47169	STR_RS05250	0.0	Capsule	Immune modulation	93.89	98.13	WP_011227246
IHHHGOGC_17	47880	48611	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
IHHHGOGC_17	47880	48611	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
IHHHGOGC_13	349153	350424	STU_RS16265	0.0	Capsule	Immune modulation	93.71	99.76	WP_011226331
IHHHGOGC_13	355999	357204	STU_RS16240	0.0	Capsule	Immune modulation	93.53	100.00	WP_011226326
IHHHGOGC_17	47880	48611	STR_RS05260	0.0	Capsule	Immune modulation	93.17	100.00	WP_011227248
IHHHGOGC_13	358255	360039	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
IHHHGOGC_13	353105	354253	STU_RS16255	0.0	Capsule	Immune modulation	92.17	100.00	WP_041828290
IHHHGOGC_10	357599	358192	STR_RS05880	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
IHHHGOGC_10	357599	358192	STER_RS06030	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
IHHHGOGC_10	357599	358192	STU_RS15260	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
IHHHGOGC_13	357224	358258	STU_RS16235	0.0	Capsule	Immune modulation	91.39	99.05	WP_002948022
IHHHGOGC_13	354250	355206	STU_RS16250	0.0	Capsule	Immune modulation	91.33	100.00	WP_011226328
IHHHGOGC_10	356730	357599	rfbA	0.0	Capsule	Immune modulation	91.03	100.00	WP_011681286
IHHHGOGC_12	365078	366736	fbp54	0.0	FBPs	Adherence	90.36	99.94	WP_011227179
IHHHGOGC_13	14388	15398	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
IHHHGOGC_17	47179	47871	STR_RS05255	0.0	Capsule	Immune modulation	88.47	99.86	WP_011227247
IHHHGOGC_17	47179	47871	STU_RS14640	0.0	Capsule	Immune modulation	88.47	99.86	WP_011226047
IHHHGOGC_10	175965	177268	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
IHHHGOGC_16	1330	2235	cbpD	0.0	Autolysin	Exoenzyme	88.41	93.50	WP_082302295
IHHHGOGC_17	47179	47871	STER_RS05310	0.0	Capsule	Immune modulation	88.18	99.86	WP_011681175
IHHHGOGC_12	209622	210383	srtA	0.0	Sortase A	Exoenzyme	84.03	99.74	-
IHHHGOGC_10	358395	359441	rfbB	0.0	Capsule	Immune modulation	80.42	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
IHHHGOGC_12	206932	205958	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.92	99.09	AAK75326
IHHHGOGC_12	218513	219586	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
IHHHGOGC_13	146384	144078	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
IHHHGOGC_10	86168	87136	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
IHHHGOGC_12	51587	50106	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
IHHHGOGC_12	246568	248814	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
IHHHGOGC_19	35936	34965	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
IHHHGOGC_13	296920	298068	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	90.08	99.48	AAL00050
IHHHGOGC_10	331345	333075	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
IHHHGOGC_13	333805	335793	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
IHHHGOGC_15	163546	162068	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
IHHHGOGC_10	175965	177266	Eno	0.0	enolase	86.44	99.77	ABP90468
IHHHGOGC_15	148223	146331	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
IHHHGOGC_12	251733	250024	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
IHHHGOGC_19	2042	951	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
IHHHGOGC_15	28754	29764	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
IHHHGOGC_12	380257	378896	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
IHHHGOGC_10	161555	162445	bglB	5.94e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
IHHHGOGC_12	292592	291642	SP_0676	1.14e-169	transcription facot	81.39	98.45	AAK74821
IHHHGOGC_12	249001	249858	metF	9.35e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
IHHHGOGC_4	426	1130	covR	3.46e-127	responder protein	85.11	100.00	AAK71319
IHHHGOGC_12	123702	124373	rr01	8.13e-127	response regulator	84.82	99.56	CAB54566
IHHHGOGC_12	255701	256372	ciaR	1.90e-124	two component system response regulator	85.71	99.12	AIK75708
IHHHGOGC_12	255701	256369	CiaR	2.36e-124	two-component response regulator	87.00	99.55	AAK74935
IHHHGOGC_4	426	1130	walR	6.35e-121	DNA-binding response regulator	81.70	100.00	ANC99504
IHHHGOGC_14	162188	162874	CovR	4.80e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
IHHHGOGC_19	777	382	SpxA2	3.99e-76	transcriptional regulator	91.67	100.00	ERL21461
IHHHGOGC_12	391723	392124	SpxA1	4.70e-69	transcriptional regulator	82.09	100.00	ERL19273
IHHHGOGC_18	6355	5942	GrpE	9.73e-68	protein grpE	81.16	80.59	ABP89267
IHHHGOGC_14	185967	186254	spr0479	5.81e-48	essential gene	85.42	98.97	AAK99283
IHHHGOGC_10	49766	50020	spr1327	2.17e-44	essential gene	92.94	100.00	AAL00131
IHHHGOGC_15	117226	117489	spr0175	9.79e-43	pathogenitcity related	85.23	100.00	AAK98979
IHHHGOGC_15	118052	118318	spr0177	1.36e-41	essential gene	83.15	88.12	AAK98981
IHHHGOGC_14	4098	4589	RopE (M5005_Spy_1611)	1.06e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
IHHHGOGC_13	146384	144084	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
IHHHGOGC_15	65476	64457	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.77	100.00	ABJ55451