Genome ID：GCA_009717205.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	20	33	38.59

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
KOIPBLHL_3	50866	51597	STR_RS05260	0.0	Capsule	Immune modulation	94.40	100.00	WP_011227248
KOIPBLHL_11	154249	155100	rfbD	0.0	Capsule	Immune modulation	94.25	100.00	WP_014621820
KOIPBLHL_3	50866	51597	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
KOIPBLHL_3	50866	51597	STER_RS05315	0.0	Capsule	Immune modulation	93.44	100.00	WP_011681176
KOIPBLHL_11	157362	158171	STU_RS16245	0.0	Capsule	Immune modulation	92.85	99.88	WP_002948020
KOIPBLHL_11	160428	162184	STU_RS16230	0.0	Capsule	Immune modulation	92.60	98.43	WP_011226325
KOIPBLHL_11	158171	159376	STU_RS16240	0.0	Capsule	Immune modulation	92.37	100.00	WP_011226326
KOIPBLHL_11	156422	157378	STU_RS16250	0.0	Capsule	Immune modulation	91.85	100.00	WP_011226328
KOIPBLHL_11	155277	156425	STU_RS16255	0.0	Capsule	Immune modulation	91.57	99.83	WP_041828290
KOIPBLHL_26	159345	161003	fbp54	0.0	FBPs	Adherence	91.14	99.94	WP_011227179
KOIPBLHL_3	49405	50865	STER_RS05320	0.0	Capsule	Immune modulation	91.13	99.86	WP_011681177
KOIPBLHL_27	32215	32808	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
KOIPBLHL_11	159397	160431	STU_RS16235	0.0	Capsule	Immune modulation	91.00	99.15	WP_002948022
KOIPBLHL_27	32215	32808	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
KOIPBLHL_27	32215	32808	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
KOIPBLHL_3	49405	50865	STU_RS14650	0.0	Capsule	Immune modulation	90.51	100.00	WP_011226049
KOIPBLHL_3	51606	52298	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
KOIPBLHL_3	49405	50865	STR_RS05265	0.0	Capsule	Immune modulation	89.83	100.00	WP_041827043
KOIPBLHL_3	51606	52298	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
KOIPBLHL_3	51606	52298	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
KOIPBLHL_31	40495	41798	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
KOIPBLHL_11	77211	78050	cbpD	0.0	Autolysin	Exoenzyme	87.87	99.88	WP_011226733
KOIPBLHL_28	14381	15394	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
KOIPBLHL_26	11342	12103	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
KOIPBLHL_27	30899	31945	rfbB	0.0	Capsule	Immune modulation	83.49	99.90	WP_002263087
KOIPBLHL_22	1240	2523	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
KOIPBLHL_27	32808	33677	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
KOIPBLHL_3	52308	52978	STU_RS14635	8.26e-150	Capsule	Immune modulation	81.13	90.28	WP_011226046
KOIPBLHL_3	52308	52978	STER_RS05305	3.84e-148	Capsule	Immune modulation	80.98	90.28	WP_011681174
KOIPBLHL_3	52308	52978	STR_RS05250	3.90e-138	Capsule	Immune modulation	80.09	89.20	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
KOIPBLHL_26	8653	7670	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
KOIPBLHL_26	20239	21312	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
KOIPBLHL_28	147584	145278	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.28	99.22	AAK74619
KOIPBLHL_29	80170	78689	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
KOIPBLHL_26	39300	41546	metE	0.0	methionine biosynthesis enzymes	92.66	100.00	AAK74738
KOIPBLHL_32	115155	116123	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
KOIPBLHL_8	4992	5963	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
KOIPBLHL_27	59050	57320	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	90.12	100.00	AAK34199
KOIPBLHL_11	142073	144061	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
KOIPBLHL_2	29775	30926	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
KOIPBLHL_9	29286	27808	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
KOIPBLHL_31	41798	40497	Eno	0.0	enolase	86.44	99.77	ABP90468
KOIPBLHL_9	13940	12048	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
KOIPBLHL_26	44468	42759	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
KOIPBLHL_8	39430	40521	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
KOIPBLHL_32	35266	34256	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
KOIPBLHL_26	174519	173158	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
KOIPBLHL_31	56206	55316	bglB	8.13e-178	putative phospho--glucosidase	87.20	99.66	AAK33487
KOIPBLHL_26	85279	84329	SP_0676	3.25e-170	transcription facot	81.39	98.45	AAK74821
KOIPBLHL_26	41736	42593	metF	9.56e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
KOIPBLHL_30	55201	54530	rr01	1.83e-127	response regulator	84.82	99.56	CAB54566
KOIPBLHL_3	17107	17811	covR	2.88e-127	responder protein	85.53	100.00	AAK71319
KOIPBLHL_26	48438	49109	ciaR	2.12e-125	two component system response regulator	86.16	99.12	AIK75708
KOIPBLHL_26	48438	49106	CiaR	3.91e-125	two-component response regulator	87.44	99.55	AAK74935
KOIPBLHL_3	17107	17811	walR	6.54e-121	DNA-binding response regulator	82.13	100.00	ANC99504
KOIPBLHL_22	167908	168594	CovR	4.84e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
KOIPBLHL_8	40694	41089	SpxA2	4.07e-76	transcriptional regulator	91.67	100.00	ERL21461
KOIPBLHL_26	185976	186377	SpxA1	1.41e-69	transcriptional regulator	82.09	100.00	ERL19273
KOIPBLHL_7	38042	38455	GrpE	2.33e-68	protein grpE	81.88	80.59	ABP89267
KOIPBLHL_22	191117	191404	spr0479	5.87e-48	essential gene	85.42	98.97	AAK99283
KOIPBLHL_32	76244	76498	spr1327	4.69e-44	essential gene	90.59	100.00	AAL00131
KOIPBLHL_10	1215	952	spr0175	1.61e-43	pathogenitcity related	85.23	100.00	AAK98979
KOIPBLHL_10	390	124	spr0177	3.57e-42	essential gene	83.15	88.12	AAK98981
KOIPBLHL_22	2690	3181	RopE (M5005_Spy_1611)	1.07e-72	probable DNA-directed RNA polymerase subunit delta	83.54	85.86	AAK34603
KOIPBLHL_28	147584	145284	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.97	98.08	MYN69560
KOIPBLHL_15	9485	10504	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451
KOIPBLHL_26	145517	146056	pnuC	2.90e-94	NAD salvage pathway importer	83.89	66.91	AAK75931