Genome ID：GCA_009717225.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	33	39.71

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
INLPJOIG_3	308514	309731	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
INLPJOIG_3	309851	311314	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
INLPJOIG_3	308514	309728	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
INLPJOIG_3	309851	311311	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
INLPJOIG_9	48654	50114	STU_RS14650	0.0	Capsule	Immune modulation	96.92	100.21	WP_011226049
INLPJOIG_9	48654	50114	STER_RS05320	0.0	Capsule	Immune modulation	96.85	100.00	WP_011681177
INLPJOIG_9	48654	50114	STR_RS05265	0.0	Capsule	Immune modulation	96.03	100.21	WP_041827043
INLPJOIG_8	127897	128706	STU_RS16245	0.0	Capsule	Immune modulation	95.31	100.00	WP_002948020
INLPJOIG_9	45049	46414	STER_RS05300	0.0	Capsule	Immune modulation	95.09	99.85	WP_011681173
INLPJOIG_8	135844	136695	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
INLPJOIG_9	46471	47211	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
INLPJOIG_9	45047	46414	STU_RS14630	0.0	Capsule	Immune modulation	94.59	100.00	WP_011226045
INLPJOIG_9	46471	47211	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
INLPJOIG_6	2648	3931	tig/ropA	0.0	Trigger factor	Stress survival	94.08	100.00	WP_011225339
INLPJOIG_9	46476	47211	STR_RS05250	0.0	Capsule	Immune modulation	93.89	98.13	WP_011227246
INLPJOIG_9	47922	48653	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
INLPJOIG_9	47922	48653	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
INLPJOIG_8	133472	134743	STU_RS16265	0.0	Capsule	Immune modulation	93.71	99.76	WP_011226331
INLPJOIG_8	126692	127897	STU_RS16240	0.0	Capsule	Immune modulation	93.53	100.00	WP_011226326
INLPJOIG_9	47922	48653	STR_RS05260	0.0	Capsule	Immune modulation	93.17	100.00	WP_011227248
INLPJOIG_8	123857	125641	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
INLPJOIG_8	129643	130791	STU_RS16255	0.0	Capsule	Immune modulation	92.17	100.00	WP_041828290
INLPJOIG_3	464661	465254	STR_RS05880	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
INLPJOIG_3	464661	465254	STER_RS06030	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
INLPJOIG_3	464661	465254	STU_RS15260	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
INLPJOIG_8	125638	126672	STU_RS16235	0.0	Capsule	Immune modulation	91.39	99.05	WP_002948022
INLPJOIG_8	128690	129646	STU_RS16250	0.0	Capsule	Immune modulation	91.33	100.00	WP_011226328
INLPJOIG_3	463792	464661	rfbA	0.0	Capsule	Immune modulation	91.03	100.00	WP_011681286
INLPJOIG_11	20712	21551	cbpD	0.0	Autolysin	Exoenzyme	90.95	100.00	WP_011226733
INLPJOIG_4	402633	404291	fbp54	0.0	FBPs	Adherence	90.36	99.94	WP_011227179
INLPJOIG_5	14388	15398	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
INLPJOIG_9	47221	47913	STR_RS05255	0.0	Capsule	Immune modulation	88.47	99.86	WP_011227247
INLPJOIG_9	47221	47913	STU_RS14640	0.0	Capsule	Immune modulation	88.47	99.86	WP_011226047
INLPJOIG_3	283027	284330	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
INLPJOIG_9	47221	47913	STER_RS05310	0.0	Capsule	Immune modulation	88.18	99.86	WP_011681175
INLPJOIG_4	247212	247973	srtA	0.0	Sortase A	Exoenzyme	84.03	99.74	-
INLPJOIG_3	465457	466503	rfbB	0.0	Capsule	Immune modulation	80.42	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
INLPJOIG_4	244522	243548	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.92	99.09	AAK75326
INLPJOIG_4	256103	257176	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
INLPJOIG_5	146384	144078	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
INLPJOIG_3	193230	194198	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
INLPJOIG_4	89177	87696	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
INLPJOIG_4	284158	286404	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
INLPJOIG_11	35936	34965	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
INLPJOIG_5	296920	298068	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	90.08	99.48	AAL00050
INLPJOIG_3	438407	440137	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
INLPJOIG_8	150091	148103	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
INLPJOIG_7	163545	162067	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
INLPJOIG_3	283027	284328	Eno	0.0	enolase	86.44	99.77	ABP90468
INLPJOIG_7	148222	146330	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
INLPJOIG_4	289323	287614	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
INLPJOIG_11	2042	951	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
INLPJOIG_7	28753	29763	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
INLPJOIG_4	417812	416451	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
INLPJOIG_3	268617	269507	bglB	7.27e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
INLPJOIG_4	330140	329190	SP_0676	1.24e-169	transcription facot	81.39	98.45	AAK74821
INLPJOIG_4	286591	287448	metF	1.02e-167	methionine biosynthesis enzymes	87.06	99.31	AAK74739
INLPJOIG_4	161292	161963	rr01	8.85e-127	response regulator	84.82	99.56	CAB54566
INLPJOIG_9	95680	94976	covR	1.56e-126	responder protein	85.11	100.00	AAK71319
INLPJOIG_4	293291	293962	ciaR	2.07e-124	two component system response regulator	85.71	99.12	AIK75708
INLPJOIG_4	293291	293959	CiaR	2.57e-124	two-component response regulator	87.00	99.55	AAK74935
INLPJOIG_9	95680	94976	walR	2.87e-120	DNA-binding response regulator	81.70	100.00	ANC99504
INLPJOIG_6	162188	162874	CovR	4.80e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
INLPJOIG_11	777	382	SpxA2	3.95e-76	transcriptional regulator	91.67	100.00	ERL21461
INLPJOIG_4	429278	429679	SpxA1	5.12e-69	transcriptional regulator	82.09	100.00	ERL19273
INLPJOIG_10	6355	5942	GrpE	9.69e-68	protein grpE	81.16	80.59	ABP89267
INLPJOIG_6	185967	186254	spr0479	5.81e-48	essential gene	85.42	98.97	AAK99283
INLPJOIG_3	156828	157082	spr1327	2.66e-44	essential gene	92.94	100.00	AAL00131
INLPJOIG_7	117225	117488	spr0175	9.79e-43	pathogenitcity related	85.23	100.00	AAK98979
INLPJOIG_7	118051	118317	spr0177	1.36e-41	essential gene	83.15	88.12	AAK98981
INLPJOIG_6	4098	4589	RopE (M5005_Spy_1611)	1.06e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
INLPJOIG_5	146384	144084	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
INLPJOIG_7	65475	64456	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.77	100.00	ABJ55451