Genome ID：GCA_009717245.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	33	39.71

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
NCKACFLB_11	303123	304340	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
NCKACFLB_11	304460	305923	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
NCKACFLB_11	303123	304337	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
NCKACFLB_11	304460	305920	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NCKACFLB_18	48654	50114	STU_RS14650	0.0	Capsule	Immune modulation	96.92	100.21	WP_011226049
NCKACFLB_18	48654	50114	STER_RS05320	0.0	Capsule	Immune modulation	96.85	100.00	WP_011681177
NCKACFLB_18	48654	50114	STR_RS05265	0.0	Capsule	Immune modulation	96.03	100.21	WP_041827043
NCKACFLB_17	75797	76606	STU_RS16245	0.0	Capsule	Immune modulation	95.31	100.00	WP_002948020
NCKACFLB_18	45049	46414	STER_RS05300	0.0	Capsule	Immune modulation	95.09	99.85	WP_011681173
NCKACFLB_17	83744	84595	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
NCKACFLB_18	46471	47211	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
NCKACFLB_18	45047	46414	STU_RS14630	0.0	Capsule	Immune modulation	94.59	100.00	WP_011226045
NCKACFLB_18	46471	47211	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
NCKACFLB_15	2681	3964	tig/ropA	0.0	Trigger factor	Stress survival	94.08	100.00	WP_011225339
NCKACFLB_18	46476	47211	STR_RS05250	0.0	Capsule	Immune modulation	93.89	98.13	WP_011227246
NCKACFLB_18	47922	48653	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
NCKACFLB_18	47922	48653	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
NCKACFLB_17	81372	82643	STU_RS16265	0.0	Capsule	Immune modulation	93.71	99.76	WP_011226331
NCKACFLB_17	74592	75797	STU_RS16240	0.0	Capsule	Immune modulation	93.53	100.00	WP_011226326
NCKACFLB_18	47922	48653	STR_RS05260	0.0	Capsule	Immune modulation	93.17	100.00	WP_011227248
NCKACFLB_17	71757	73541	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
NCKACFLB_17	77543	78691	STU_RS16255	0.0	Capsule	Immune modulation	92.17	100.00	WP_041828290
NCKACFLB_11	459102	459695	STR_RS05880	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
NCKACFLB_11	459102	459695	STER_RS06030	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
NCKACFLB_11	459102	459695	STU_RS15260	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
NCKACFLB_17	73538	74572	STU_RS16235	0.0	Capsule	Immune modulation	91.39	99.05	WP_002948022
NCKACFLB_17	76590	77546	STU_RS16250	0.0	Capsule	Immune modulation	91.33	100.00	WP_011226328
NCKACFLB_11	458233	459102	rfbA	0.0	Capsule	Immune modulation	91.03	100.00	WP_011681286
NCKACFLB_13	365078	366736	fbp54	0.0	FBPs	Adherence	90.36	99.94	WP_011227179
NCKACFLB_14	14421	15431	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
NCKACFLB_18	47221	47913	STR_RS05255	0.0	Capsule	Immune modulation	88.47	99.86	WP_011227247
NCKACFLB_18	47221	47913	STU_RS14640	0.0	Capsule	Immune modulation	88.47	99.86	WP_011226047
NCKACFLB_11	277636	278939	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
NCKACFLB_11	98531	99436	cbpD	0.0	Autolysin	Exoenzyme	88.41	93.50	WP_082302295
NCKACFLB_18	47221	47913	STER_RS05310	0.0	Capsule	Immune modulation	88.18	99.86	WP_011681175
NCKACFLB_13	209622	210383	srtA	0.0	Sortase A	Exoenzyme	84.03	99.74	-
NCKACFLB_11	459898	460944	rfbB	0.0	Capsule	Immune modulation	80.42	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NCKACFLB_13	206932	205958	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.92	99.09	AAK75326
NCKACFLB_13	218513	219586	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
NCKACFLB_14	146417	144111	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
NCKACFLB_11	187839	188807	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
NCKACFLB_13	51587	50106	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
NCKACFLB_13	246568	248814	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
NCKACFLB_20	9735	10706	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
NCKACFLB_14	296953	298101	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	90.08	99.48	AAL00050
NCKACFLB_11	432848	434578	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
NCKACFLB_17	97991	96003	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
NCKACFLB_16	163545	162067	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
NCKACFLB_11	277636	278937	Eno	0.0	enolase	86.44	99.77	ABP90468
NCKACFLB_16	148222	146330	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
NCKACFLB_13	251733	250024	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
NCKACFLB_20	43629	44720	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
NCKACFLB_16	28753	29763	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
NCKACFLB_13	380257	378896	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
NCKACFLB_11	263226	264116	bglB	6.72e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
NCKACFLB_13	292592	291642	SP_0676	1.14e-169	transcription facot	81.39	98.45	AAK74821
NCKACFLB_13	249001	249858	metF	9.36e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
NCKACFLB_4	426	1130	covR	3.44e-127	responder protein	85.11	100.00	AAK71319
NCKACFLB_13	123702	124373	rr01	8.14e-127	response regulator	84.82	99.56	CAB54566
NCKACFLB_13	255701	256372	ciaR	1.90e-124	two component system response regulator	85.71	99.12	AIK75708
NCKACFLB_13	255701	256369	CiaR	2.36e-124	two-component response regulator	87.00	99.55	AAK74935
NCKACFLB_4	426	1130	walR	6.32e-121	DNA-binding response regulator	81.70	100.00	ANC99504
NCKACFLB_15	162221	162907	CovR	4.80e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
NCKACFLB_20	44894	45289	SpxA2	4.48e-76	transcriptional regulator	91.67	100.00	ERL21461
NCKACFLB_13	391723	392124	SpxA1	4.71e-69	transcriptional regulator	82.09	100.00	ERL19273
NCKACFLB_19	6542	6129	GrpE	9.73e-68	protein grpE	81.16	80.59	ABP89267
NCKACFLB_15	186000	186287	spr0479	5.81e-48	essential gene	85.42	98.97	AAK99283
NCKACFLB_11	151437	151691	spr1327	2.46e-44	essential gene	92.94	100.00	AAL00131
NCKACFLB_16	117225	117488	spr0175	9.79e-43	pathogenitcity related	85.23	100.00	AAK98979
NCKACFLB_16	118051	118317	spr0177	1.36e-41	essential gene	83.15	88.12	AAK98981
NCKACFLB_15	4131	4622	RopE (M5005_Spy_1611)	1.06e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
NCKACFLB_14	146417	144117	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
NCKACFLB_16	65475	64456	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.77	100.00	ABJ55451