Genome ID：GCA_009717265.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	33	39.71

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
FDKOIPGK_15	308513	309730	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
FDKOIPGK_15	309850	311313	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
FDKOIPGK_15	308513	309727	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
FDKOIPGK_15	309850	311310	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
FDKOIPGK_20	48654	50114	STU_RS14650	0.0	Capsule	Immune modulation	96.92	100.21	WP_011226049
FDKOIPGK_20	48654	50114	STER_RS05320	0.0	Capsule	Immune modulation	96.85	100.00	WP_011681177
FDKOIPGK_20	48654	50114	STR_RS05265	0.0	Capsule	Immune modulation	96.03	100.21	WP_041827043
FDKOIPGK_19	76112	76921	STU_RS16245	0.0	Capsule	Immune modulation	95.31	100.00	WP_002948020
FDKOIPGK_20	45049	46414	STER_RS05300	0.0	Capsule	Immune modulation	95.09	99.85	WP_011681173
FDKOIPGK_19	84059	84910	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
FDKOIPGK_20	46471	47211	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
FDKOIPGK_20	45047	46414	STU_RS14630	0.0	Capsule	Immune modulation	94.59	100.00	WP_011226045
FDKOIPGK_20	46471	47211	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
FDKOIPGK_17	2648	3931	tig/ropA	0.0	Trigger factor	Stress survival	94.08	100.00	WP_011225339
FDKOIPGK_20	46476	47211	STR_RS05250	0.0	Capsule	Immune modulation	93.89	98.13	WP_011227246
FDKOIPGK_20	47922	48653	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
FDKOIPGK_20	47922	48653	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
FDKOIPGK_19	81687	82958	STU_RS16265	0.0	Capsule	Immune modulation	93.71	99.76	WP_011226331
FDKOIPGK_19	74907	76112	STU_RS16240	0.0	Capsule	Immune modulation	93.53	100.00	WP_011226326
FDKOIPGK_20	47922	48653	STR_RS05260	0.0	Capsule	Immune modulation	93.17	100.00	WP_011227248
FDKOIPGK_19	72072	73856	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
FDKOIPGK_19	77858	79006	STU_RS16255	0.0	Capsule	Immune modulation	92.17	100.00	WP_041828290
FDKOIPGK_15	464827	465420	STR_RS05880	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
FDKOIPGK_15	464827	465420	STER_RS06030	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
FDKOIPGK_15	464827	465420	STU_RS15260	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
FDKOIPGK_19	73853	74887	STU_RS16235	0.0	Capsule	Immune modulation	91.39	99.05	WP_002948022
FDKOIPGK_19	76905	77861	STU_RS16250	0.0	Capsule	Immune modulation	91.33	100.00	WP_011226328
FDKOIPGK_15	463958	464827	rfbA	0.0	Capsule	Immune modulation	91.03	100.00	WP_011681286
FDKOIPGK_11	58774	60432	fbp54	0.0	FBPs	Adherence	90.36	99.94	WP_011227179
FDKOIPGK_16	313196	314206	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
FDKOIPGK_20	47221	47913	STR_RS05255	0.0	Capsule	Immune modulation	88.47	99.86	WP_011227247
FDKOIPGK_20	47221	47913	STU_RS14640	0.0	Capsule	Immune modulation	88.47	99.86	WP_011226047
FDKOIPGK_15	283026	284329	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
FDKOIPGK_15	103921	104826	cbpD	0.0	Autolysin	Exoenzyme	88.41	93.50	WP_082302295
FDKOIPGK_20	47221	47913	STER_RS05310	0.0	Capsule	Immune modulation	88.18	99.86	WP_011681175
FDKOIPGK_11	214959	215720	srtA	0.0	Sortase A	Exoenzyme	84.03	99.74	-
FDKOIPGK_15	465623	466669	rfbB	0.0	Capsule	Immune modulation	80.42	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
FDKOIPGK_11	218410	219384	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.92	99.09	AAK75326
FDKOIPGK_11	206829	205756	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
FDKOIPGK_16	182210	184516	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
FDKOIPGK_15	193229	194197	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
FDKOIPGK_11	373755	375236	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
FDKOIPGK_11	178774	176528	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
FDKOIPGK_1	35936	34965	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
FDKOIPGK_16	31674	30526	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	90.08	99.48	AAL00050
FDKOIPGK_15	438573	440303	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
FDKOIPGK_19	98306	96318	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
FDKOIPGK_18	163545	162067	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
FDKOIPGK_15	283026	284327	Eno	0.0	enolase	86.44	99.77	ABP90468
FDKOIPGK_18	148222	146330	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
FDKOIPGK_11	173609	175318	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
FDKOIPGK_1	2042	951	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
FDKOIPGK_18	28753	29763	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
FDKOIPGK_11	45253	46614	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
FDKOIPGK_15	268616	269506	bglB	6.77e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
FDKOIPGK_11	132918	133868	SP_0676	1.14e-169	transcription facot	81.39	98.45	AAK74821
FDKOIPGK_11	176341	175484	metF	9.35e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
FDKOIPGK_4	426	1130	covR	3.37e-127	responder protein	85.11	100.00	AAK71319
FDKOIPGK_11	301640	300969	rr01	8.13e-127	response regulator	84.82	99.56	CAB54566
FDKOIPGK_11	169641	168970	ciaR	1.90e-124	two component system response regulator	85.71	99.12	AIK75708
FDKOIPGK_11	169641	168973	CiaR	2.36e-124	two-component response regulator	87.00	99.55	AAK74935
FDKOIPGK_4	426	1130	walR	6.19e-121	DNA-binding response regulator	81.70	100.00	ANC99504
FDKOIPGK_17	162188	162874	CovR	4.80e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
FDKOIPGK_1	777	382	SpxA2	3.95e-76	transcriptional regulator	91.67	100.00	ERL21461
FDKOIPGK_11	33787	33386	SpxA1	4.70e-69	transcriptional regulator	82.09	100.00	ERL19273
FDKOIPGK_21	6355	5942	GrpE	9.69e-68	protein grpE	81.16	80.59	ABP89267
FDKOIPGK_17	185967	186254	spr0479	5.81e-48	essential gene	85.42	98.97	AAK99283
FDKOIPGK_15	156827	157081	spr1327	2.48e-44	essential gene	92.94	100.00	AAL00131
FDKOIPGK_18	117225	117488	spr0175	9.79e-43	pathogenitcity related	85.23	100.00	AAK98979
FDKOIPGK_18	118051	118317	spr0177	1.36e-41	essential gene	83.15	88.12	AAK98981
FDKOIPGK_17	4098	4589	RopE (M5005_Spy_1611)	1.06e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
FDKOIPGK_16	182210	184510	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
FDKOIPGK_18	65475	64456	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.77	100.00	ABJ55451