Genome ID：GCA_009717305.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	16	33	36.67

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HMPMLPCN_20	17372	18103	STER_RS05315	0.0	Capsule	Immune modulation	94.81	100.00	WP_011681176
HMPMLPCN_20	17372	18103	STU_RS14645	0.0	Capsule	Immune modulation	94.54	100.00	WP_011226048
HMPMLPCN_12	12055	12906	rfbD	0.0	Capsule	Immune modulation	94.48	100.00	WP_014621820
HMPMLPCN_12	8614	9330	STER_RS07085	0.0	Capsule	Immune modulation	94.42	100.00	WP_011681442
HMPMLPCN_20	17372	18103	STR_RS05260	0.0	Capsule	Immune modulation	94.13	100.00	WP_011227248
HMPMLPCN_12	7498	8268	STER_RS07075	0.0	Capsule	Immune modulation	92.35	99.23	WP_011681440
HMPMLPCN_14	1184	1777	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
HMPMLPCN_20	18104	19564	STER_RS05320	0.0	Capsule	Immune modulation	90.92	99.86	WP_011681177
HMPMLPCN_14	1184	1777	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
HMPMLPCN_14	1184	1777	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
HMPMLPCN_20	18104	19564	STU_RS14650	0.0	Capsule	Immune modulation	90.78	100.00	WP_011226049
HMPMLPCN_9	3441	5098	fbp54	0.0	FBPs	Adherence	90.36	99.88	WP_011227179
HMPMLPCN_20	18104	19564	STR_RS05265	0.0	Capsule	Immune modulation	89.97	100.00	WP_041827043
HMPMLPCN_20	16671	17363	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
HMPMLPCN_20	16671	17363	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
HMPMLPCN_20	16671	17363	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
HMPMLPCN_3	34490	35793	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
HMPMLPCN_33	72419	73258	cbpD	0.0	Autolysin	Exoenzyme	87.87	99.88	WP_011226733
HMPMLPCN_11	64519	65280	srtA	0.0	Sortase A	Exoenzyme	86.65	99.74	-
HMPMLPCN_25	13638	14651	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
HMPMLPCN_14	3	914	rfbB	0.0	Capsule	Immune modulation	84.34	87.01	WP_002263087
HMPMLPCN_10	41383	42666	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753
HMPMLPCN_14	1777	2646	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
HMPMLPCN_20	15991	16661	STU_RS14635	1.17e-148	Capsule	Immune modulation	80.98	90.28	WP_011226046
HMPMLPCN_20	15991	16661	STER_RS05305	5.46e-147	Capsule	Immune modulation	80.83	90.28	WP_011681174
HMPMLPCN_20	16059	16661	STR_RS05250	5.54e-137	Capsule	Immune modulation	81.46	80.13	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HMPMLPCN_11	61830	60847	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
HMPMLPCN_11	73412	74485	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
HMPMLPCN_58	96760	99066	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
HMPMLPCN_55	36426	37907	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
HMPMLPCN_11	92953	95199	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
HMPMLPCN_44	13648	12680	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
HMPMLPCN_13	23827	22856	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
HMPMLPCN_11	133	6606	PrtA	0.0	serine protease	91.35	100.61	ABJ55268
HMPMLPCN_28	1936	206	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
HMPMLPCN_12	26586	24598	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
HMPMLPCN_44	89781	88630	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
HMPMLPCN_5	7293	8771	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
HMPMLPCN_3	34490	35791	Eno	0.0	enolase	86.44	99.77	ABP90468
HMPMLPCN_5	23073	24965	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
HMPMLPCN_26	12594	13685	recA	0.0	DNA recombination and repair	84.91	95.36	AAL00560
HMPMLPCN_11	98117	96408	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
HMPMLPCN_9	18859	17498	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
HMPMLPCN_1	20178	21188	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
HMPMLPCN_3	20080	20970	bglB	8.51e-178	putative phospho--glucosidase	87.20	99.66	AAK33487
HMPMLPCN_11	95389	96246	metF	4.68e-170	methionine biosynthesis enzymes	87.76	99.31	AAK74739
HMPMLPCN_11	139668	138730	SP_0676	9.66e-169	transcription facot	81.47	97.20	AAK74821
HMPMLPCN_18	1815	2519	covR	1.87e-128	responder protein	85.96	100.00	AAK71319
HMPMLPCN_7	23818	23147	rr01	5.10e-127	response regulator	84.38	99.56	CAB54566
HMPMLPCN_11	102782	103453	ciaR	1.78e-125	two component system response regulator	86.16	99.12	AIK75708
HMPMLPCN_11	102782	103450	CiaR	3.25e-125	two-component response regulator	87.44	99.55	AAK74935
HMPMLPCN_6	27493	28179	CovR	5.34e-121	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
HMPMLPCN_18	1815	2519	walR	1.13e-120	DNA-binding response regulator	81.70	100.00	ANC99504
HMPMLPCN_9	30317	30718	SpxA1	2.54e-70	transcriptional regulator	82.09	100.00	ERL19273
HMPMLPCN_10	27606	28019	GrpE	4.23e-68	protein grpE	81.88	80.59	ABP89267
HMPMLPCN_6	50693	50980	spr0479	1.69e-48	essential gene	85.42	98.97	AAK99283
HMPMLPCN_44	47310	47056	spr1327	4.03e-46	essential gene	94.12	100.00	AAL00131
HMPMLPCN_5	54252	53989	spr0175	3.52e-43	pathogenitcity related	85.23	100.00	AAK98979
HMPMLPCN_5	53427	53161	spr0177	7.81e-42	essential gene	83.15	88.12	AAK98981
HMPMLPCN_10	42833	43324	RopE (M5005_Spy_1611)	2.63e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
HMPMLPCN_58	96760	99060	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
HMPMLPCN_1	56592	55573	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451