Genome ID：GCA_009717325.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	23	33	40.27

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
HNMCMCAK_9	33473	34936	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302
HNMCMCAK_9	35056	36273	mef(A)	Erythromycin, Azithromycin	99.92	100.00	U83667

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
HNMCMCAK_9	35059	36273	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
HNMCMCAK_9	33476	34936	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HNMCMCAK_7	73663	74514	rfbD	0.0	Capsule	Immune modulation	95.19	100.00	WP_014621820
HNMCMCAK_8	205190	205930	STER_RS05305	0.0	Capsule	Immune modulation	95.01	100.00	WP_011681174
HNMCMCAK_8	205190	205930	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
HNMCMCAK_8	202287	203747	STU_RS14650	0.0	Capsule	Immune modulation	94.11	100.14	WP_011226049
HNMCMCAK_8	202287	203747	STER_RS05320	0.0	Capsule	Immune modulation	93.98	100.00	WP_011681177
HNMCMCAK_8	205987	207354	STU_RS14630	0.0	Capsule	Immune modulation	93.93	100.00	WP_011226045
HNMCMCAK_8	205190	205925	STR_RS05250	0.0	Capsule	Immune modulation	93.75	98.13	WP_011227246
HNMCMCAK_8	205987	207352	STER_RS05300	0.0	Capsule	Immune modulation	93.63	99.85	WP_011681173
HNMCMCAK_7	71291	72562	STU_RS16265	0.0	Capsule	Immune modulation	93.47	99.76	WP_011226331
HNMCMCAK_8	202287	203747	STR_RS05265	0.0	Capsule	Immune modulation	93.22	100.14	WP_041827043
HNMCMCAK_7	65715	66524	STU_RS16245	0.0	Capsule	Immune modulation	93.09	100.00	WP_002948020
HNMCMCAK_7	61674	63458	STU_RS16230	0.0	Capsule	Immune modulation	92.94	100.00	WP_011226325
HNMCMCAK_7	66508	67464	STU_RS16250	0.0	Capsule	Immune modulation	92.37	100.00	WP_011226328
HNMCMCAK_7	67461	68609	STU_RS16255	0.0	Capsule	Immune modulation	92.34	100.00	WP_041828290
HNMCMCAK_7	64510	65715	STU_RS16240	0.0	Capsule	Immune modulation	92.12	100.00	WP_011226326
HNMCMCAK_8	203748	204479	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
HNMCMCAK_8	25980	26573	STR_RS05880	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
HNMCMCAK_8	25980	26573	STER_RS06030	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
HNMCMCAK_8	25980	26573	STU_RS15260	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
HNMCMCAK_8	203748	204479	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
HNMCMCAK_8	25111	25980	rfbA	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681286
HNMCMCAK_7	63455	64489	STU_RS16235	0.0	Capsule	Immune modulation	91.10	99.15	WP_002948022
HNMCMCAK_8	203748	204479	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
HNMCMCAK_2	20615	21454	cbpD	0.0	Autolysin	Exoenzyme	90.96	99.88	WP_011226733
HNMCMCAK_8	315229	316887	fbp54	0.0	FBPs	Adherence	90.48	99.94	WP_011227179
HNMCMCAK_1	23359	24369	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
HNMCMCAK_8	204488	205180	STR_RS05255	0.0	Capsule	Immune modulation	88.04	99.86	WP_011227247
HNMCMCAK_8	204488	205180	STU_RS14640	0.0	Capsule	Immune modulation	88.04	99.86	WP_011226047
HNMCMCAK_8	204488	205180	STER_RS05310	0.0	Capsule	Immune modulation	87.46	99.86	WP_011681175
HNMCMCAK_9	55810	57113	eno	0.0	Streptococcal enolase	Exoenzyme	87.25	99.54	WP_000022832
HNMCMCAK_13	114859	115620	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
HNMCMCAK_8	26845	27891	rfbB	0.0	Capsule	Immune modulation	80.92	99.90	WP_009659423
HNMCMCAK_10	213218	214501	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
HNMCMCAK_8	215489	216074	SPD_RS01775	7.25e-147	Capsule	Immune modulation	82.96	96.53	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HNMCMCAK_13	118308	119282	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.31	99.09	AAK75326
HNMCMCAK_13	106724	105651	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
HNMCMCAK_7	249131	251437	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
HNMCMCAK_9	144384	143416	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
HNMCMCAK_12	106588	105107	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
HNMCMCAK_13	87181	84935	metE	0.0	methionine biosynthesis enzymes	92.12	100.00	AAK74738
HNMCMCAK_2	35876	34905	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
HNMCMCAK_14	97987	99717	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
HNMCMCAK_7	86784	84796	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
HNMCMCAK_7	115153	114002	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
HNMCMCAK_11	185221	183743	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
HNMCMCAK_9	57113	55812	Eno	0.0	enolase	86.44	99.77	ABP90468
HNMCMCAK_11	169848	167956	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
HNMCMCAK_13	82016	83725	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
HNMCMCAK_2	2037	946	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
HNMCMCAK_11	28537	29547	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
HNMCMCAK_8	296656	298017	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
HNMCMCAK_9	71517	70627	bglB	1.86e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
HNMCMCAK_13	42749	43699	SP_0676	2.75e-170	transcription facot	81.39	98.45	AAK74821
HNMCMCAK_13	84748	83891	metF	4.35e-169	methionine biosynthesis enzymes	87.76	99.31	AAK74739
HNMCMCAK_12	169144	169815	rr01	3.49e-127	response regulator	84.82	99.56	CAB54566
HNMCMCAK_8	149228	149932	covR	1.52e-126	responder protein	85.53	100.00	AAK71319
HNMCMCAK_13	78049	77378	ciaR	1.10e-124	two component system response regulator	85.71	99.12	AIK75708
HNMCMCAK_13	78049	77381	CiaR	1.13e-124	two-component response regulator	87.00	99.55	AAK74935
HNMCMCAK_8	149228	149932	walR	3.46e-120	DNA-binding response regulator	82.13	100.00	ANC99504
HNMCMCAK_10	63346	62660	CovR	4.73e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
HNMCMCAK_2	772	377	SpxA2	3.94e-76	transcriptional regulator	91.67	100.00	ERL21461
HNMCMCAK_8	285188	284787	SpxA1	6.99e-70	transcriptional regulator	82.84	100.00	ERL19273
HNMCMCAK_15	6604	6191	GrpE	3.80e-68	protein grpE	81.88	80.59	ABP89267
HNMCMCAK_10	30655	30368	spr0479	4.58e-48	essential gene	85.42	98.97	AAK99283
HNMCMCAK_9	178141	177887	spr1327	1.48e-44	essential gene	92.94	100.00	AAL00131
HNMCMCAK_11	120669	120932	spr0175	1.09e-42	pathogenitcity related	85.23	100.00	AAK98979
HNMCMCAK_11	121493	121759	spr0177	2.42e-41	essential gene	83.15	88.12	AAK98981
HNMCMCAK_10	213051	212560	RopE (M5005_Spy_1611)	1.05e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
HNMCMCAK_7	249131	251431	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
HNMCMCAK_11	64985	63966	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451