Genome ID：GCA_009717435.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	19	34	39.00

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
JANNFLOH_11	221442	222905	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302
JANNFLOH_11	223025	224242	mef(A)	Erythromycin, Azithromycin	99.92	100.00	U83667

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
JANNFLOH_11	223028	224242	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
JANNFLOH_11	221445	222905	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
JANNFLOH_16	146987	147955	STER_RS07090	0.0	Capsule	Immune modulation	98.14	100.00	WP_011681443
JANNFLOH_16	147957	148672	STER_RS07085	0.0	Capsule	Immune modulation	96.79	99.86	WP_011681442
JANNFLOH_16	144766	146019	STER_RS07100	0.0	Capsule	Immune modulation	96.49	99.52	WP_011681445
JANNFLOH_16	143796	144647	rfbD	0.0	Capsule	Immune modulation	94.25	100.00	WP_014621820
JANNFLOH_15	176705	178165	STU_RS14650	0.0	Capsule	Immune modulation	93.98	100.14	WP_011226049
JANNFLOH_15	176705	178165	STER_RS05320	0.0	Capsule	Immune modulation	93.98	100.00	WP_011681177
JANNFLOH_15	173097	174464	STU_RS14630	0.0	Capsule	Immune modulation	93.20	100.00	WP_011226045
JANNFLOH_16	149018	149788	STER_RS07075	0.0	Capsule	Immune modulation	93.14	99.10	WP_011681440
JANNFLOH_11	80572	81165	STR_RS05880	0.0	Capsule	Immune modulation	93.10	100.00	WP_011226149
JANNFLOH_15	176705	178165	STR_RS05265	0.0	Capsule	Immune modulation	93.09	100.14	WP_041827043
JANNFLOH_15	173099	174464	STER_RS05300	0.0	Capsule	Immune modulation	93.05	99.85	WP_011681173
JANNFLOH_11	80572	81165	STER_RS06030	0.0	Capsule	Immune modulation	92.93	100.00	WP_011226149
JANNFLOH_11	80572	81165	STU_RS15260	0.0	Capsule	Immune modulation	92.93	100.00	WP_011226149
JANNFLOH_15	175973	176704	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
JANNFLOH_15	175973	176704	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
JANNFLOH_15	174522	175262	STER_RS05305	0.0	Capsule	Immune modulation	91.51	99.87	WP_011681174
JANNFLOH_11	81165	82034	rfbA	0.0	Capsule	Immune modulation	91.49	100.00	WP_011681286
JANNFLOH_15	175973	176704	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
JANNFLOH_15	72039	73697	fbp54	0.0	FBPs	Adherence	90.60	99.94	WP_011227179
JANNFLOH_15	174522	175262	STU_RS14635	0.0	Capsule	Immune modulation	90.57	99.87	WP_011226046
JANNFLOH_4	23427	24266	cbpD	0.0	Autolysin	Exoenzyme	90.48	100.00	WP_011226733
JANNFLOH_15	174527	175262	STR_RS05250	0.0	Capsule	Immune modulation	90.23	98.00	WP_011227246
JANNFLOH_11	286973	288276	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
JANNFLOH_21	14391	15401	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.56	99.80	WP_002986042
JANNFLOH_1	84700	85461	srtA	0.0	Sortase A	Exoenzyme	86.52	99.74	-
JANNFLOH_15	175272	175964	STU_RS14640	0.0	Capsule	Immune modulation	85.45	99.86	WP_011226047
JANNFLOH_15	175272	175964	STR_RS05255	0.0	Capsule	Immune modulation	85.16	99.86	WP_011227247
JANNFLOH_15	175272	175964	STER_RS05310	0.0	Capsule	Immune modulation	84.87	99.86	WP_011681175
JANNFLOH_17	2693	3976	tig/ropA	0.0	Trigger factor	Stress survival	81.07	99.61	WP_000107753
JANNFLOH_11	79261	80307	rfbB	0.0	Capsule	Immune modulation	80.71	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
JANNFLOH_1	76569	75496	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
JANNFLOH_1	88150	89124	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.00	99.09	AAK75326
JANNFLOH_2	56061	58367	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
JANNFLOH_20	106143	104662	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
JANNFLOH_1	57472	55226	metE	0.0	methionine biosynthesis enzymes	93.06	100.00	AAK74738
JANNFLOH_11	378045	377077	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
JANNFLOH_4	38691	37720	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
JANNFLOH_20	218308	224856	PrtA	0.0	serine protease	90.35	101.73	ABJ55268
JANNFLOH_11	107414	105684	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
JANNFLOH_16	101974	103125	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
JANNFLOH_16	130352	132340	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
JANNFLOH_18	25882	27360	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
JANNFLOH_11	288276	286975	Eno	0.0	enolase	86.44	99.77	ABP90468
JANNFLOH_18	41223	43115	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.42	98.90	ABP91129
JANNFLOH_1	52304	54013	PGM	0.0	phosphoglucomutase	84.94	99.65	ACH87041
JANNFLOH_4	2042	951	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
JANNFLOH_18	157028	156018	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
JANNFLOH_15	87468	86107	mnmE	0.0	central tRNA-modifying GTPase	81.80	99.56	ABP90420
JANNFLOH_11	302682	301792	bglB	2.24e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
JANNFLOH_1	10815	11753	SP_0676	7.60e-170	transcription facot	81.79	97.20	AAK74821
JANNFLOH_1	55036	54179	metF	3.85e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
JANNFLOH_15	223770	223066	covR	4.10e-126	responder protein	85.11	100.00	AAK71319
JANNFLOH_20	181112	181783	rr01	5.81e-126	response regulator	84.38	99.56	CAB54566
JANNFLOH_1	47639	46968	ciaR	8.52e-126	two component system response regulator	86.16	99.12	AIK75708
JANNFLOH_1	47639	46971	CiaR	1.58e-125	two-component response regulator	87.44	99.55	AAK74935
JANNFLOH_17	161547	162233	CovR	4.74e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
JANNFLOH_15	223770	223066	walR	7.53e-120	DNA-binding response regulator	81.70	100.00	ANC99504
JANNFLOH_4	776	381	SpxA2	4.22e-76	transcriptional regulator	91.67	100.00	ERL21461
JANNFLOH_15	98935	99336	SpxA1	2.87e-69	transcriptional regulator	82.09	100.00	ERL19273
JANNFLOH_3	46703	47116	GrpE	3.43e-67	protein grpE	80.44	80.59	ABP89267
JANNFLOH_17	184758	185045	spr0479	5.74e-48	essential gene	85.42	98.97	AAK99283
JANNFLOH_19	30370	30116	spr1327	8.06e-45	essential gene	92.94	100.00	AAL00131
JANNFLOH_18	72223	71960	spr0175	9.60e-43	pathogenitcity related	85.23	100.00	AAK98979
JANNFLOH_18	71397	71131	spr0177	1.34e-41	essential gene	83.15	88.12	AAK98981
JANNFLOH_17	4143	4634	RopE (M5005_Spy_1611)	1.05e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
JANNFLOH_2	56061	58361	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
JANNFLOH_18	120341	121360	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451