Genome ID：GCA_010500735.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	22	33	39.66

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HICLADAD_40	19688	20557	rfbA	0.0	Capsule	Immune modulation	99.89	100.00	WP_011681286
HICLADAD_40	20557	21150	STER_RS06030	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
HICLADAD_1	147103	147912	STU_RS16245	0.0	Capsule	Immune modulation	99.75	100.00	WP_002948020
HICLADAD_40	20557	21150	STR_RS05880	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
HICLADAD_36	91360	93018	fbp54	0.0	FBPs	Adherence	99.64	100.00	WP_011227179
HICLADAD_40	20557	21150	STU_RS15260	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226149
HICLADAD_1	148849	149997	STU_RS16255	0.0	Capsule	Immune modulation	99.30	100.00	WP_041828290
HICLADAD_1	147896	148852	STU_RS16250	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226328
HICLADAD_1	143044	144826	STU_RS16230	0.0	Capsule	Immune modulation	99.10	99.89	WP_011226325
HICLADAD_39	13460	14200	STU_RS14635	0.0	Capsule	Immune modulation	98.92	100.00	WP_011226046
HICLADAD_1	145898	147103	STU_RS16240	0.0	Capsule	Immune modulation	98.92	100.00	WP_011226326
HICLADAD_39	13460	14200	STER_RS05305	0.0	Capsule	Immune modulation	98.78	100.00	WP_011681174
HICLADAD_39	81637	82429	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.49	100.13	-
HICLADAD_1	144823	145878	STU_RS16235	0.0	Capsule	Immune modulation	98.48	100.00	WP_002948022
HICLADAD_1	151421	152272	rfbD	0.0	Capsule	Immune modulation	98.36	100.00	WP_014621820
HICLADAD_39	13465	14200	STR_RS05250	0.0	Capsule	Immune modulation	98.23	98.13	WP_011227246
HICLADAD_24	87470	88429	cbpD	0.0	Autolysin	Exoenzyme	98.04	99.90	WP_082302295
HICLADAD_39	15643	17103	STER_RS05320	0.0	Capsule	Immune modulation	97.74	100.00	WP_011681177
HICLADAD_39	14911	15642	STER_RS05315	0.0	Capsule	Immune modulation	97.68	100.00	WP_011681176
HICLADAD_39	14911	15642	STU_RS14645	0.0	Capsule	Immune modulation	97.68	100.00	WP_011226048
HICLADAD_4	14822	15583	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
HICLADAD_39	14911	15642	STR_RS05260	0.0	Capsule	Immune modulation	97.54	100.00	WP_011227248
HICLADAD_39	14210	14902	STER_RS05310	0.0	Capsule	Immune modulation	97.26	100.00	WP_011681175
HICLADAD_39	15643	17103	STU_RS14650	0.0	Capsule	Immune modulation	96.58	100.21	WP_011226049
HICLADAD_39	15643	17103	STR_RS05265	0.0	Capsule	Immune modulation	95.76	100.21	WP_041827043
HICLADAD_39	12038	13403	STER_RS05300	0.0	Capsule	Immune modulation	95.09	99.85	WP_011681173
HICLADAD_39	12036	13403	STU_RS14630	0.0	Capsule	Immune modulation	94.01	100.00	WP_011226045
HICLADAD_39	14210	14902	STU_RS14640	0.0	Capsule	Immune modulation	90.62	100.00	WP_011226047
HICLADAD_39	14210	14902	STR_RS05255	0.0	Capsule	Immune modulation	90.04	100.00	WP_011227247
HICLADAD_13	94525	95828	eno	0.0	Streptococcal enolase	Exoenzyme	88.10	99.46	WP_000022832
HICLADAD_14	14535	15545	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.46	99.80	WP_002986042
HICLADAD_3	54139	55422	tig/ropA	0.0	Trigger factor	Stress survival	80.73	99.77	WP_000107753
HICLADAD_40	21579	22625	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HICLADAD_4	18270	19253	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.51	100.00	AAK75326
HICLADAD_11	25102	26175	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
HICLADAD_2	120998	118695	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
HICLADAD_13	12215	13183	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
HICLADAD_1	47882	49363	SPD_0310	0.0	UPF0371 protein SPD_0310	92.11	100.00	ABJ54480
HICLADAD_9	11752	9506	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
HICLADAD_7	2344	1346	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
HICLADAD_7	48025	47054	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
HICLADAD_1	195291	194140	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.06	99.74	AAL00050
HICLADAD_1	166898	164910	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
HICLADAD_4	2073	343	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.04	100.00	AAK34199
HICLADAD_37	28847	30325	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
HICLADAD_13	94525	95826	Eno	0.0	enolase	86.21	99.77	ABP90468
HICLADAD_37	44036	45928	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
HICLADAD_9	6582	8291	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
HICLADAD_12	2274	1264	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
HICLADAD_36	70195	71556	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
HICLADAD_38	50004	48112	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
HICLADAD_13	80088	80978	bglB	1.21e-179	putative phospho--glucosidase	88.89	99.66	AAK33487
HICLADAD_6	37056	37994	SP_0676	9.74e-169	transcription facot	81.15	97.20	AAK74821
HICLADAD_9	9314	8457	metF	1.38e-166	methionine biosynthesis enzymes	86.36	99.31	AAK74739
HICLADAD_39	53950	53246	covR	1.97e-132	responder protein	85.53	100.00	AAK71319
HICLADAD_1	10011	9340	rr01	3.63e-125	response regulator	83.93	99.56	CAB54566
HICLADAD_39	53950	53246	walR	8.32e-123	DNA-binding response regulator	82.13	100.00	ANC99504
HICLADAD_9	2628	1960	CiaR	3.24e-119	two-component response regulator	84.31	99.55	AAK74935
HICLADAD_35	48180	47494	CovR	7.56e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
HICLADAD_9	2628	1957	ciaR	3.18e-117	two component system response regulator	82.14	99.12	AIK75708
HICLADAD_7	1070	696	SpxA2	3.27e-71	transcriptional regulator	91.20	94.70	ERL21461
HICLADAD_36	58832	58431	SpxA1	2.16e-67	transcriptional regulator	80.60	100.00	ERL19273
HICLADAD_35	25798	25511	spr0479	1.07e-48	essential gene	86.46	98.97	AAK99283
HICLADAD_24	129193	129447	spr1327	2.40e-45	essential gene	95.29	100.00	AAL00131
HICLADAD_37	77664	77401	spr0175	3.42e-42	pathogenitcity related	84.09	100.00	AAK98979
HICLADAD_37	76837	76571	spr0177	7.47e-34	essential gene	84.27	88.12	AAK98981
HICLADAD_3	53981	53481	RopE (M5005_Spy_1611)	1.61e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
HICLADAD_2	120998	118701	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
HICLADAD_38	35544	34525	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451