Genome ID：GCA_013267495.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	28	34.47

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
PEHBHELM_1	521988	523907	tet(M)	ARO:3000186	tet(M)	98.90	100.00	AB039845.1
PEHBHELM_1	520144	520881	ErmB	ARO:3000375	ErmB	97.96	98.79	AF242872.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
PEHBHELM_1	520144	520881	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	U86375
PEHBHELM_1	521988	523907	tet(M)	Doxycycline, Tetracycline, Minocycline	99.64	100.00	X92947

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
PEHBHELM_1	520147	520881	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038790.1
PEHBHELM_1	521991	523907	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	EXACTX	100.00	100.00	WP_000691736.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
PEHBHELM_1	612934	613649	STER_RS07085	0.0	Capsule	Immune modulation	96.51	99.86	WP_011681442
PEHBHELM_1	616958	617809	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
PEHBHELM_1	98015	98755	STER_RS05305	0.0	Capsule	Immune modulation	95.01	100.00	WP_011681174
PEHBHELM_1	613651	614619	STER_RS07090	0.0	Capsule	Immune modulation	94.94	100.00	WP_011681443
PEHBHELM_1	98015	98755	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
PEHBHELM_1	98812	100177	STER_RS05300	0.0	Capsule	Immune modulation	94.00	99.85	WP_011681173
PEHBHELM_1	98015	98750	STR_RS05250	0.0	Capsule	Immune modulation	93.75	98.13	WP_011227246
PEHBHELM_1	95112	96572	STER_RS05320	0.0	Capsule	Immune modulation	93.63	100.00	WP_011681177
PEHBHELM_1	95112	96572	STU_RS14650	0.0	Capsule	Immune modulation	93.57	100.21	WP_011226049
PEHBHELM_1	98812	100179	STU_RS14630	0.0	Capsule	Immune modulation	93.57	100.00	WP_011226045
PEHBHELM_1	95112	96572	STR_RS05265	0.0	Capsule	Immune modulation	92.81	100.21	WP_041827043
PEHBHELM_1	611812	612588	STER_RS07075	0.0	Capsule	Immune modulation	92.66	100.00	WP_011681440
PEHBHELM_1	615586	616839	STER_RS07100	0.0	Capsule	Immune modulation	92.34	99.44	WP_011681445
PEHBHELM_1	96573	97304	STU_RS14645	0.0	Capsule	Immune modulation	92.08	100.00	WP_011226048
PEHBHELM_1	96573	97304	STER_RS05315	0.0	Capsule	Immune modulation	91.67	100.00	WP_011681176
PEHBHELM_1	1920402	1920995	STR_RS05880	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
PEHBHELM_1	1920402	1920995	STER_RS06030	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
PEHBHELM_1	1920402	1920995	STU_RS15260	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
PEHBHELM_1	1919533	1920402	rfbA	0.0	Capsule	Immune modulation	91.15	100.00	WP_011681286
PEHBHELM_1	96573	97304	STR_RS05260	0.0	Capsule	Immune modulation	91.12	100.00	WP_011227248
PEHBHELM_1	1168030	1168869	cbpD	0.0	Autolysin	Exoenzyme	91.07	100.00	WP_011226733
PEHBHELM_1	206613	208271	fbp54	0.0	FBPs	Adherence	90.66	99.94	WP_011227179
PEHBHELM_1	914984	915994	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.55	99.80	WP_002986042
PEHBHELM_1	1743490	1744793	eno	0.0	Streptococcal enolase	Exoenzyme	88.32	99.54	WP_000022832
PEHBHELM_1	97313	98005	STR_RS05255	0.0	Capsule	Immune modulation	87.90	99.86	WP_011227247
PEHBHELM_1	97313	98005	STU_RS14640	0.0	Capsule	Immune modulation	87.90	99.86	WP_011226047
PEHBHELM_1	97313	98005	STER_RS05310	0.0	Capsule	Immune modulation	87.32	99.86	WP_011681175
PEHBHELM_1	352739	353500	srtA	0.0	Sortase A	Exoenzyme	85.21	99.74	-
PEHBHELM_1	1921198	1922244	rfbB	0.0	Capsule	Immune modulation	80.90	100.00	WP_009659423
PEHBHELM_1	1257569	1258852	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
PEHBHELM_1	111006	111589	SPD_RS01775	1.16e-156	Capsule	Immune modulation	84.13	96.04	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
PEHBHELM_1	356189	357172	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.04	100.00	AAK75326
PEHBHELM_1	344604	343531	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
PEHBHELM_1	796157	798463	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.67	99.22	AAK74619
PEHBHELM_1	325545	323299	metE	0.0	methionine biosynthesis enzymes	93.06	100.00	AAK74738
PEHBHELM_1	491304	492785	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
PEHBHELM_1	1650169	1651137	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
PEHBHELM_1	1153609	1154580	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
PEHBHELM_1	1894150	1895880	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
PEHBHELM_1	631243	629255	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
PEHBHELM_1	659603	658452	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
PEHBHELM_1	1118081	1116603	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
PEHBHELM_1	1743490	1744791	Eno	0.0	enolase	86.44	99.77	ABP90468
PEHBHELM_1	1101102	1099210	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
PEHBHELM_1	1188161	1189252	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
PEHBHELM_1	192149	193510	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
PEHBHELM_1	969823	970833	pdh	1.59e-177	pyruvate dehydrogenase	83.98	99.70	ABP91006
PEHBHELM_1	1729071	1729961	bglB	2.17e-176	putative phospho--glucosidase	87.20	99.66	AAK33487
PEHBHELM_1	280509	281459	SP_0676	2.36e-169	transcription facot	81.39	98.45	AAK74821
PEHBHELM_1	323109	322252	metF	6.62e-169	methionine biosynthesis enzymes	87.76	99.31	AAK74739
PEHBHELM_1	49429	50133	covR	8.92e-126	responder protein	85.53	100.00	AAK71319
PEHBHELM_1	418276	417605	rr01	3.61e-125	response regulator	84.38	99.56	CAB54566
PEHBHELM_1	315716	315045	ciaR	2.51e-124	two component system response regulator	86.16	99.12	AIK75708
PEHBHELM_1	315716	315048	CiaR	4.60e-124	two-component response regulator	87.44	99.55	AAK74935
PEHBHELM_1	49429	50133	walR	2.03e-119	DNA-binding response regulator	82.13	100.00	ANC99504
PEHBHELM_1	1400122	1400808	CovR	4.38e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
PEHBHELM_1	1189427	1189822	SpxA2	1.97e-74	transcriptional regulator	91.67	100.00	ERL21461
PEHBHELM_1	180692	180291	SpxA1	6.28e-69	transcriptional regulator	82.09	100.00	ERL19273
PEHBHELM_1	1243904	1244317	GrpE	1.56e-66	protein grpE	81.88	80.59	ABP89267
PEHBHELM_1	1259019	1259510	RopE (M5005_Spy_1611)	9.68e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
PEHBHELM_1	796157	798457	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.36	98.08	MYN69560
PEHBHELM_1	1006241	1005222	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451