Genome ID：GCA_015159825.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	16	36	39.40

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
JOHDHDGE_11	181294	182025	STR_RS05260	0.0	Capsule	Immune modulation	94.54	100.00	WP_011227248
JOHDHDGE_44	23795	24511	STER_RS07085	0.0	Capsule	Immune modulation	94.42	100.00	WP_011681442
JOHDHDGE_44	20219	21070	rfbD	0.0	Capsule	Immune modulation	94.37	100.00	WP_014621820
JOHDHDGE_11	181294	182025	STU_RS14645	0.0	Capsule	Immune modulation	93.85	100.00	WP_011226048
JOHDHDGE_11	181294	182025	STER_RS05315	0.0	Capsule	Immune modulation	93.58	100.00	WP_011681176
JOHDHDGE_44	24857	25627	STER_RS07075	0.0	Capsule	Immune modulation	92.35	99.23	WP_011681440
JOHDHDGE_11	182026	183486	STER_RS05320	0.0	Capsule	Immune modulation	91.26	99.86	WP_011681177
JOHDHDGE_6	7699	8292	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
JOHDHDGE_6	7699	8292	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
JOHDHDGE_6	7699	8292	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
JOHDHDGE_11	182026	183486	STU_RS14650	0.0	Capsule	Immune modulation	90.65	100.00	WP_011226049
JOHDHDGE_11	79117	80774	fbp54	0.0	FBPs	Adherence	90.30	99.88	WP_011227179
JOHDHDGE_11	182026	183486	STR_RS05265	0.0	Capsule	Immune modulation	89.97	100.00	WP_041827043
JOHDHDGE_11	180593	181285	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
JOHDHDGE_11	180593	181285	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
JOHDHDGE_11	180593	181285	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
JOHDHDGE_4	38085	39388	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
JOHDHDGE_88	12513	13352	cbpD	0.0	Autolysin	Exoenzyme	87.87	99.88	WP_011226733
JOHDHDGE_13	16189	17202	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
JOHDHDGE_22	80693	81454	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
JOHDHDGE_6	6383	7429	rfbB	0.0	Capsule	Immune modulation	83.59	99.90	WP_002263087
JOHDHDGE_20	8443	9726	tig/ropA	0.0	Trigger factor	Stress survival	80.76	99.61	WP_000107753
JOHDHDGE_6	8292	9161	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
JOHDHDGE_11	179913	180583	STU_RS14635	2.96e-149	Capsule	Immune modulation	81.13	90.28	WP_011226046
JOHDHDGE_11	179913	180583	STER_RS05305	1.38e-147	Capsule	Immune modulation	80.98	90.28	WP_011681174
JOHDHDGE_11	179913	180583	STR_RS05250	1.40e-137	Capsule	Immune modulation	80.09	89.20	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
JOHDHDGE_22	84143	85126	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
JOHDHDGE_22	72555	71482	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
JOHDHDGE_55	119137	121443	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
JOHDHDGE_3	26876	27844	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
JOHDHDGE_77	5782	7263	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
JOHDHDGE_22	53495	51249	metE	0.0	methionine biosynthesis enzymes	92.66	100.00	AAK74738
JOHDHDGE_22	133096	126623	PrtA	0.0	serine protease	91.48	100.61	ABJ55268
JOHDHDGE_9	4974	5945	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
JOHDHDGE_6	34537	32807	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
JOHDHDGE_44	5086	7074	uvrB	0.0	excinuclease ABC, B subunit	89.74	100.00	AE014259_2
JOHDHDGE_5	25708	24557	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
JOHDHDGE_10	29517	28039	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
JOHDHDGE_4	39388	38087	Eno	0.0	enolase	86.44	99.77	ABP90468
JOHDHDGE_10	14176	12284	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
JOHDHDGE_22	48331	50040	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
JOHDHDGE_9	38060	39151	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
JOHDHDGE_11	94536	93175	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
JOHDHDGE_66	19904	20914	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
JOHDHDGE_4	53794	52904	bglB	7.62e-179	putative phospho--glucosidase	87.88	99.66	AAK33487
JOHDHDGE_22	8362	9312	SP_0676	2.74e-170	transcription facot	81.39	98.45	AAK74821
JOHDHDGE_22	51059	50202	metF	8.05e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
JOHDHDGE_87	18644	19501	mtsA	2.56e-152	substrate-binding lipoprotein of manganese transporter	80.49	92.86	AIK76191
JOHDHDGE_44	20219	21040	GacA	2.97e-147	dTDP-4-dehydrorhamnose reductas	80.29	96.48	AAZ51220
JOHDHDGE_22	150951	150280	rr01	3.99e-127	response regulator	84.82	99.56	CAB54566
JOHDHDGE_11	215794	215090	covR	1.47e-126	responder protein	85.53	100.00	AAK71319
JOHDHDGE_22	43666	42995	ciaR	1.78e-125	two component system response regulator	86.16	99.12	AIK75708
JOHDHDGE_22	43666	42998	CiaR	3.29e-125	two-component response regulator	87.44	99.55	AAK74935
JOHDHDGE_33	53873	53187	CovR	1.48e-120	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
JOHDHDGE_11	215794	215090	walR	1.31e-119	DNA-binding response regulator	81.70	100.00	ANC99504
JOHDHDGE_9	39324	39719	SpxA2	3.92e-76	transcriptional regulator	91.67	100.00	ERL21461
JOHDHDGE_11	105993	106394	SpxA1	1.48e-69	transcriptional regulator	82.09	100.00	ERL19273
JOHDHDGE_7	45912	46325	GrpE	4.07e-68	protein grpE	81.88	80.59	ABP89267
JOHDHDGE_33	30666	30379	spr0479	4.69e-48	essential gene	85.42	98.97	AAK99283
JOHDHDGE_15	4876	4622	spr1327	1.52e-45	essential gene	91.77	100.00	AAL00131
JOHDHDGE_66	110688	110951	spr0175	5.78e-43	pathogenitcity related	85.23	100.00	AAK98979
JOHDHDGE_66	111513	111779	spr0177	1.28e-41	essential gene	83.15	88.12	AAK98981
JOHDHDGE_20	8276	7785	RopE (M5005_Spy_1611)	5.08e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
JOHDHDGE_55	119137	121437	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
JOHDHDGE_66	56044	55025	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451
JOHDHDGE_11	66131	66670	pnuC	1.28e-98	NAD salvage pathway importer	88.89	66.91	AAK75931