Genome ID：GCA_017367085.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	25	33	41.40

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
ICNKMEIA_5	39664	40473	STU_RS16245	0.0	Capsule	Immune modulation	99.88	100.00	WP_002948020
ICNKMEIA_5	38724	39680	STU_RS16250	0.0	Capsule	Immune modulation	99.79	100.00	WP_011226328
ICNKMEIA_5	37579	38727	STU_RS16255	0.0	Capsule	Immune modulation	99.74	100.00	WP_041828290
ICNKMEIA_5	33232	34083	rfbD	0.0	Capsule	Immune modulation	99.65	100.00	WP_014621820
ICNKMEIA_28	1729	3387	fbp54	0.0	FBPs	Adherence	99.64	100.00	WP_011227179
ICNKMEIA_5	40473	41678	STU_RS16240	0.0	Capsule	Immune modulation	99.58	100.00	WP_011226326
ICNKMEIA_5	36460	37470	STU_RS16260	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226330
ICNKMEIA_5	41698	42753	STU_RS16235	0.0	Capsule	Immune modulation	99.43	100.00	WP_002948022
ICNKMEIA_17	19511	20380	rfbA	0.0	Capsule	Immune modulation	99.42	100.00	WP_011681286
ICNKMEIA_5	42750	44534	STU_RS16230	0.0	Capsule	Immune modulation	99.38	100.00	WP_011226325
ICNKMEIA_17	20380	20973	STR_RS05880	0.0	Capsule	Immune modulation	99.33	100.00	WP_011226149
ICNKMEIA_17	20380	20973	STER_RS06030	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226149
ICNKMEIA_17	20380	20973	STU_RS15260	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226149
ICNKMEIA_20	66061	66756	STU_RS14640	0.0	Capsule	Immune modulation	99.14	100.29	WP_011226047
ICNKMEIA_20	66061	66756	STR_RS05255	0.0	Capsule	Immune modulation	98.56	100.29	WP_011227247
ICNKMEIA_41	236408	237376	cbpD	0.0	Autolysin	Exoenzyme	98.35	99.90	WP_082302295
ICNKMEIA_19	992	1785	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.24	100.25	-
ICNKMEIA_20	65321	66052	STU_RS14645	0.0	Capsule	Immune modulation	98.22	100.00	WP_011226048
ICNKMEIA_20	63860	65320	STER_RS05320	0.0	Capsule	Immune modulation	98.02	100.00	WP_011681177
ICNKMEIA_20	65321	66052	STER_RS05315	0.0	Capsule	Immune modulation	97.95	100.00	WP_011681176
ICNKMEIA_21	999	2414	STER_RS05250	0.0	Capsule	Immune modulation	97.88	100.00	WP_011681165
ICNKMEIA_11	30295	31056	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
ICNKMEIA_20	65321	66052	STR_RS05260	0.0	Capsule	Immune modulation	97.54	100.00	WP_011227248
ICNKMEIA_5	35186	36457	STU_RS16265	0.0	Capsule	Immune modulation	97.48	99.76	WP_011226331
ICNKMEIA_20	63860	65320	STU_RS14650	0.0	Capsule	Immune modulation	97.26	100.21	WP_011226049
ICNKMEIA_20	63860	65320	STR_RS05265	0.0	Capsule	Immune modulation	96.30	100.21	WP_041827043
ICNKMEIA_20	66766	67524	STER_RS05305	0.0	Capsule	Immune modulation	95.52	100.94	WP_011681174
ICNKMEIA_20	66766	67524	STU_RS14635	0.0	Capsule	Immune modulation	95.39	100.94	WP_011226046
ICNKMEIA_20	67581	68946	STER_RS05300	0.0	Capsule	Immune modulation	95.24	99.85	WP_011681173
ICNKMEIA_20	66766	67519	STR_RS05250	0.0	Capsule	Immune modulation	94.56	99.07	WP_011227246
ICNKMEIA_20	67581	68948	STU_RS14630	0.0	Capsule	Immune modulation	94.01	100.00	WP_011226045
ICNKMEIA_20	66061	66756	STER_RS05310	0.0	Capsule	Immune modulation	89.08	100.29	WP_011681175
ICNKMEIA_41	76117	77420	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
ICNKMEIA_58	12651	13661	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.44	99.41	WP_002986042
ICNKMEIA_50	63720	65003	tig/ropA	0.0	Trigger factor	Stress survival	80.73	99.77	WP_000107753
ICNKMEIA_17	21403	22449	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
ICNKMEIA_11	27608	26625	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
ICNKMEIA_40	13785	12712	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
ICNKMEIA_41	161105	160137	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
ICNKMEIA_2	15666	13363	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
ICNKMEIA_8	79614	78133	SPD_0310	0.0	UPF0371 protein SPD_0310	92.31	100.00	ABJ54480
ICNKMEIA_39	11392	9146	metE	0.0	methionine biosynthesis enzymes	91.72	100.00	AAK74738
ICNKMEIA_54	2015	1017	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
ICNKMEIA_55	27455	26484	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
ICNKMEIA_4	73229	74380	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
ICNKMEIA_5	18262	20250	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
ICNKMEIA_11	43816	45546	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.04	100.00	AAK34199
ICNKMEIA_50	103923	105401	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
ICNKMEIA_41	77420	76119	Eno	0.0	enolase	86.21	99.77	ABP90468
ICNKMEIA_50	119112	121004	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
ICNKMEIA_39	6221	7930	PGM	0.0	phosphoglucomutase	83.71	99.65	ACH87041
ICNKMEIA_34	2109	1099	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
ICNKMEIA_27	68435	69796	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
ICNKMEIA_12	26127	28019	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
ICNKMEIA_41	91855	90965	bglB	1.81e-179	putative phospho--glucosidase	88.89	99.66	AAK33487
ICNKMEIA_31	43976	44914	SP_0676	6.01e-169	transcription facot	81.15	97.20	AAK74821
ICNKMEIA_39	8954	8097	metF	1.47e-166	methionine biosynthesis enzymes	86.36	99.31	AAK74739
ICNKMEIA_20	27059	27763	covR	1.73e-132	responder protein	85.53	100.00	AAK71319
ICNKMEIA_8	120806	121477	rr01	2.09e-125	response regulator	83.93	99.56	CAB54566
ICNKMEIA_20	27059	27763	walR	7.30e-123	DNA-binding response regulator	82.13	100.00	ANC99504
ICNKMEIA_39	2267	1599	CiaR	1.96e-119	two-component response regulator	84.31	99.55	AAK74935
ICNKMEIA_48	8207	7521	CovR	4.42e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
ICNKMEIA_39	2267	1596	ciaR	1.93e-117	two component system response regulator	82.14	99.12	AIK75708
ICNKMEIA_54	741	367	SpxA2	9.50e-72	transcriptional regulator	91.20	94.70	ERL21461
ICNKMEIA_27	57075	56674	SpxA1	2.53e-67	transcriptional regulator	80.60	100.00	ERL19273
ICNKMEIA_47	25528	25241	spr0479	3.04e-49	essential gene	86.46	98.97	AAK99283
ICNKMEIA_41	195518	195264	spr1327	3.75e-45	essential gene	95.29	100.00	AAL00131
ICNKMEIA_50	174366	174103	spr0175	8.80e-42	pathogenitcity related	84.09	100.00	AAK98979
ICNKMEIA_50	173539	173273	spr0177	1.56e-33	essential gene	84.27	88.12	AAK98981
ICNKMEIA_50	63562	63062	RopE (M5005_Spy_1611)	4.89e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
ICNKMEIA_2	15666	13369	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
ICNKMEIA_12	40599	41618	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451