Genome ID：GCA_017367115.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	25	33	41.40

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
EDFCFBJD_4	40214	41023	STU_RS16245	0.0	Capsule	Immune modulation	99.88	100.00	WP_002948020
EDFCFBJD_4	39274	40230	STU_RS16250	0.0	Capsule	Immune modulation	99.79	100.00	WP_011226328
EDFCFBJD_4	38129	39277	STU_RS16255	0.0	Capsule	Immune modulation	99.74	100.00	WP_041828290
EDFCFBJD_4	33782	34633	rfbD	0.0	Capsule	Immune modulation	99.65	100.00	WP_014621820
EDFCFBJD_25	1729	3387	fbp54	0.0	FBPs	Adherence	99.64	100.00	WP_011227179
EDFCFBJD_4	41023	42228	STU_RS16240	0.0	Capsule	Immune modulation	99.58	100.00	WP_011226326
EDFCFBJD_4	37010	38020	STU_RS16260	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226330
EDFCFBJD_4	42248	43303	STU_RS16235	0.0	Capsule	Immune modulation	99.43	100.00	WP_002948022
EDFCFBJD_14	19511	20380	rfbA	0.0	Capsule	Immune modulation	99.42	100.00	WP_011681286
EDFCFBJD_4	43300	45084	STU_RS16230	0.0	Capsule	Immune modulation	99.38	100.00	WP_011226325
EDFCFBJD_14	20380	20973	STR_RS05880	0.0	Capsule	Immune modulation	99.33	100.00	WP_011226149
EDFCFBJD_14	20380	20973	STER_RS06030	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226149
EDFCFBJD_14	20380	20973	STU_RS15260	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226149
EDFCFBJD_17	14264	14959	STU_RS14640	0.0	Capsule	Immune modulation	99.14	100.29	WP_011226047
EDFCFBJD_17	14264	14959	STR_RS05255	0.0	Capsule	Immune modulation	98.56	100.29	WP_011227247
EDFCFBJD_39	236416	237384	cbpD	0.0	Autolysin	Exoenzyme	98.35	99.90	WP_082302295
EDFCFBJD_15	850	1643	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.24	100.25	-
EDFCFBJD_17	13524	14255	STU_RS14645	0.0	Capsule	Immune modulation	98.22	100.00	WP_011226048
EDFCFBJD_17	12063	13523	STER_RS05320	0.0	Capsule	Immune modulation	98.02	100.00	WP_011681177
EDFCFBJD_17	13524	14255	STER_RS05315	0.0	Capsule	Immune modulation	97.95	100.00	WP_011681176
EDFCFBJD_19	623	2038	STER_RS05250	0.0	Capsule	Immune modulation	97.88	100.00	WP_011681165
EDFCFBJD_10	30295	31056	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
EDFCFBJD_17	13524	14255	STR_RS05260	0.0	Capsule	Immune modulation	97.54	100.00	WP_011227248
EDFCFBJD_4	35736	37007	STU_RS16265	0.0	Capsule	Immune modulation	97.48	99.76	WP_011226331
EDFCFBJD_17	12063	13523	STU_RS14650	0.0	Capsule	Immune modulation	97.26	100.21	WP_011226049
EDFCFBJD_17	12063	13523	STR_RS05265	0.0	Capsule	Immune modulation	96.30	100.21	WP_041827043
EDFCFBJD_17	14969	15727	STER_RS05305	0.0	Capsule	Immune modulation	95.52	100.94	WP_011681174
EDFCFBJD_17	14969	15727	STU_RS14635	0.0	Capsule	Immune modulation	95.39	100.94	WP_011226046
EDFCFBJD_17	15784	17149	STER_RS05300	0.0	Capsule	Immune modulation	95.24	99.85	WP_011681173
EDFCFBJD_17	14969	15722	STR_RS05250	0.0	Capsule	Immune modulation	94.56	99.07	WP_011227246
EDFCFBJD_17	15784	17151	STU_RS14630	0.0	Capsule	Immune modulation	94.01	100.00	WP_011226045
EDFCFBJD_17	14264	14959	STER_RS05310	0.0	Capsule	Immune modulation	89.08	100.29	WP_011681175
EDFCFBJD_39	76117	77420	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
EDFCFBJD_24	98402	99412	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.44	99.41	WP_002986042
EDFCFBJD_46	63720	65003	tig/ropA	0.0	Trigger factor	Stress survival	80.73	99.77	WP_000107753
EDFCFBJD_14	21403	22449	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
EDFCFBJD_10	27608	26625	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
EDFCFBJD_38	14335	13262	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
EDFCFBJD_39	161105	160137	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
EDFCFBJD_2	15666	13363	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
EDFCFBJD_7	79614	78133	SPD_0310	0.0	UPF0371 protein SPD_0310	92.31	100.00	ABJ54480
EDFCFBJD_37	11392	9146	metE	0.0	methionine biosynthesis enzymes	91.72	100.00	AAK74738
EDFCFBJD_51	2015	1017	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
EDFCFBJD_52	27455	26484	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
EDFCFBJD_3	73087	74238	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
EDFCFBJD_4	18812	20800	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
EDFCFBJD_10	43816	45546	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.04	100.00	AAK34199
EDFCFBJD_46	103921	105399	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
EDFCFBJD_39	77420	76119	Eno	0.0	enolase	86.21	99.77	ABP90468
EDFCFBJD_46	119110	121002	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
EDFCFBJD_37	6221	7930	PGM	0.0	phosphoglucomutase	83.71	99.65	ACH87041
EDFCFBJD_34	2109	1099	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
EDFCFBJD_24	67571	68932	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
EDFCFBJD_12	27058	28950	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
EDFCFBJD_39	91855	90965	bglB	1.81e-179	putative phospho--glucosidase	88.89	99.66	AAK33487
EDFCFBJD_28	44352	45290	SP_0676	6.06e-169	transcription facot	81.15	97.20	AAK74821
EDFCFBJD_37	8954	8097	metF	1.47e-166	methionine biosynthesis enzymes	86.36	99.31	AAK74739
EDFCFBJD_16	27059	27763	covR	1.21e-132	responder protein	85.53	100.00	AAK71319
EDFCFBJD_7	120806	121477	rr01	2.73e-125	response regulator	83.93	99.56	CAB54566
EDFCFBJD_16	27059	27763	walR	5.08e-123	DNA-binding response regulator	82.13	100.00	ANC99504
EDFCFBJD_37	2267	1599	CiaR	1.96e-119	two-component response regulator	84.31	99.55	AAK74935
EDFCFBJD_43	9474	8788	CovR	4.49e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
EDFCFBJD_37	2267	1596	ciaR	1.93e-117	two component system response regulator	82.14	99.12	AIK75708
EDFCFBJD_51	741	367	SpxA2	9.50e-72	transcriptional regulator	91.20	94.70	ERL21461
EDFCFBJD_24	56211	55810	SpxA1	2.89e-67	transcriptional regulator	80.60	100.00	ERL19273
EDFCFBJD_7	143096	143383	spr0479	1.29e-48	essential gene	86.46	98.97	AAK99283
EDFCFBJD_39	195526	195272	spr1327	3.75e-45	essential gene	95.29	100.00	AAL00131
EDFCFBJD_46	174364	174101	spr0175	8.80e-42	pathogenitcity related	84.09	100.00	AAK98979
EDFCFBJD_46	173537	173271	spr0177	1.56e-33	essential gene	84.27	88.12	AAK98981
EDFCFBJD_46	63562	63062	RopE (M5005_Spy_1611)	4.89e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
EDFCFBJD_2	15666	13369	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
EDFCFBJD_12	41530	42549	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451