Genome ID：GCA_018531105.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	35	40.36

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
HDOFDFCB_7	37465	38682	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
HDOFDFCB_7	35882	37345	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
HDOFDFCB_7	37468	38682	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
HDOFDFCB_7	35885	37345	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HDOFDFCB_7	107510	108241	STER_RS05315	0.0	Capsule	Immune modulation	94.81	100.00	WP_011681176
HDOFDFCB_7	107510	108241	STU_RS14645	0.0	Capsule	Immune modulation	94.54	100.00	WP_011226048
HDOFDFCB_63	114478	115329	rfbD	0.0	Capsule	Immune modulation	94.13	100.00	WP_014621820
HDOFDFCB_7	107510	108241	STR_RS05260	0.0	Capsule	Immune modulation	94.13	100.00	WP_011227248
HDOFDFCB_63	111407	112216	STU_RS16245	0.0	Capsule	Immune modulation	92.85	99.88	WP_002948020
HDOFDFCB_63	107394	109150	STU_RS16230	0.0	Capsule	Immune modulation	92.60	98.43	WP_011226325
HDOFDFCB_63	110202	111407	STU_RS16240	0.0	Capsule	Immune modulation	92.37	100.00	WP_011226326
HDOFDFCB_63	112200	113156	STU_RS16250	0.0	Capsule	Immune modulation	91.85	100.00	WP_011226328
HDOFDFCB_63	113153	114301	STU_RS16255	0.0	Capsule	Immune modulation	91.57	99.83	WP_041828290
HDOFDFCB_1	33938	34531	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
HDOFDFCB_26	19806	21464	fbp54	0.0	FBPs	Adherence	91.08	99.94	WP_011227179
HDOFDFCB_63	109147	110181	STU_RS16235	0.0	Capsule	Immune modulation	91.00	99.15	WP_002948022
HDOFDFCB_7	108242	109702	STER_RS05320	0.0	Capsule	Immune modulation	90.92	99.86	WP_011681177
HDOFDFCB_1	33938	34531	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
HDOFDFCB_1	33938	34531	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
HDOFDFCB_7	108242	109702	STU_RS14650	0.0	Capsule	Immune modulation	90.78	100.00	WP_011226049
HDOFDFCB_7	108242	109702	STR_RS05265	0.0	Capsule	Immune modulation	89.97	100.00	WP_041827043
HDOFDFCB_22	10243	11148	cbpD	0.0	Autolysin	Exoenzyme	89.96	93.50	WP_082302295
HDOFDFCB_7	106809	107501	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
HDOFDFCB_7	106809	107501	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
HDOFDFCB_7	106809	107501	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
HDOFDFCB_18	55176	56479	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
HDOFDFCB_24	13420	14430	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.28	99.80	WP_002986042
HDOFDFCB_61	148159	148920	srtA	0.0	Sortase A	Exoenzyme	83.88	99.87	-
HDOFDFCB_1	32637	33668	rfbB	0.0	Capsule	Immune modulation	83.64	98.47	WP_002263087
HDOFDFCB_42	1803	3086	tig/ropA	0.0	Trigger factor	Stress survival	80.53	99.61	WP_000107753
HDOFDFCB_1	34531	35400	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
HDOFDFCB_7	106129	106799	STU_RS14635	6.54e-148	Capsule	Immune modulation	80.98	90.28	WP_011226046
HDOFDFCB_7	106129	106799	STER_RS05305	3.04e-146	Capsule	Immune modulation	80.83	90.28	WP_011681174
HDOFDFCB_7	106197	106799	STR_RS05250	3.09e-136	Capsule	Immune modulation	81.46	80.13	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HDOFDFCB_61	151610	152593	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
HDOFDFCB_61	140023	138950	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
HDOFDFCB_52	9420	7114	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
HDOFDFCB_11	24010	23042	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
HDOFDFCB_61	120968	118722	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
HDOFDFCB_3	77777	76296	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
HDOFDFCB_23	36358	35387	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
HDOFDFCB_14	52193	45720	PrtA	0.0	serine protease	91.44	100.61	ABJ55268
HDOFDFCB_1	60776	59046	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
HDOFDFCB_63	128960	126972	uvrB	0.0	excinuclease ABC, B subunit	89.74	100.00	AE014259_2
HDOFDFCB_52	149726	150877	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
HDOFDFCB_6	88538	87060	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
HDOFDFCB_18	56479	55178	Eno	0.0	enolase	86.44	99.77	ABP90468
HDOFDFCB_6	73197	71305	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
HDOFDFCB_61	115804	117513	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
HDOFDFCB_23	1216	125	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
HDOFDFCB_21	19513	20523	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
HDOFDFCB_26	5880	7241	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
HDOFDFCB_20	13824	12934	bglB	6.15e-178	putative phospho--glucosidase	87.20	99.66	AAK33487
HDOFDFCB_61	75838	76788	SP_0676	2.25e-170	transcription facot	81.39	98.45	AAK74821
HDOFDFCB_61	118532	117675	metF	5.04e-170	methionine biosynthesis enzymes	87.76	99.31	AAK74739
HDOFDFCB_1	97643	98500	mtsA	3.92e-152	substrate-binding lipoprotein of manganese transporter	80.49	92.86	AIK76191
HDOFDFCB_36	13762	14466	covR	1.09e-127	responder protein	85.53	100.00	AAK71319
HDOFDFCB_14	70170	69499	rr01	1.59e-127	response regulator	84.82	99.56	CAB54566
HDOFDFCB_61	111138	110467	ciaR	6.80e-125	two component system response regulator	85.71	99.12	AIK75708
HDOFDFCB_61	111138	110470	CiaR	8.46e-125	two-component response regulator	87.00	99.55	AAK74935
HDOFDFCB_12	41748	42434	CovR	6.54e-121	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
HDOFDFCB_36	13762	14466	walR	9.71e-121	DNA-binding response regulator	81.70	100.00	ANC99504
HDOFDFCB_59	206	601	SpxA2	3.56e-85	transcriptional regulator	91.67	100.00	ERL21461
HDOFDFCB_7	5796	6197	SpxA1	7.03e-70	transcriptional regulator	82.09	100.00	ERL19273
HDOFDFCB_38	6085	5672	GrpE	1.31e-69	protein grpE	82.61	80.59	ABP89267
HDOFDFCB_12	64953	65240	spr0479	2.07e-48	essential gene	85.42	98.97	AAK99283
HDOFDFCB_11	59791	59537	spr1327	2.97e-44	essential gene	90.59	100.00	AAL00131
HDOFDFCB_6	24653	24916	spr0175	5.93e-43	pathogenitcity related	85.23	100.00	AAK98979
HDOFDFCB_6	25478	25744	spr0177	1.32e-41	essential gene	83.15	88.12	AAK98981
HDOFDFCB_42	3253	3744	RopE (M5005_Spy_1611)	6.88e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
HDOFDFCB_52	9420	7120	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
HDOFDFCB_31	23260	24279	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451