Genome ID：GCA_018783545.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	16	34	37.63

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
EMDINGLP_23	523925	525388	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	99.93	100.00	AF274302
EMDINGLP_23	525508	526725	mef(A)	Erythromycin, Azithromycin	99.92	100.00	U83667

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
EMDINGLP_23	525511	526725	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
EMDINGLP_23	523928	525388	msr(D)	ABC-F type ribosomal protection protein Msr(D)	BLASTX	99.79	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
EMDINGLP_23	149944	151309	STER_RS05300	0.0	Capsule	Immune modulation	95.46	99.85	WP_011681173
EMDINGLP_23	149942	151309	STU_RS14630	0.0	Capsule	Immune modulation	94.96	100.00	WP_011226045
EMDINGLP_48	25836	26687	rfbD	0.0	Capsule	Immune modulation	94.37	100.00	WP_014621820
EMDINGLP_23	153549	155009	STU_RS14650	0.0	Capsule	Immune modulation	94.25	100.14	WP_011226049
EMDINGLP_23	151366	152106	STER_RS05305	0.0	Capsule	Immune modulation	94.20	100.00	WP_011681174
EMDINGLP_23	366115	367161	rfbB	0.0	Capsule	Immune modulation	94.17	100.00	WP_002947383
EMDINGLP_23	153549	155009	STER_RS05320	0.0	Capsule	Immune modulation	94.11	100.00	WP_011681177
EMDINGLP_23	153549	155009	STR_RS05265	0.0	Capsule	Immune modulation	93.36	100.14	WP_041827043
EMDINGLP_23	151366	152106	STU_RS14635	0.0	Capsule	Immune modulation	93.12	100.00	WP_011226046
EMDINGLP_23	151371	152106	STR_RS05250	0.0	Capsule	Immune modulation	92.94	98.13	WP_011227246
EMDINGLP_23	367364	367957	STR_RS05880	0.0	Capsule	Immune modulation	92.59	100.00	WP_011226149
EMDINGLP_23	367364	367957	STER_RS06030	0.0	Capsule	Immune modulation	92.42	100.00	WP_011226149
EMDINGLP_23	367364	367957	STU_RS15260	0.0	Capsule	Immune modulation	92.42	100.00	WP_011226149
EMDINGLP_23	152817	153548	STU_RS14645	0.0	Capsule	Immune modulation	91.53	100.00	WP_011226048
EMDINGLP_23	152817	153548	STER_RS05315	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681176
EMDINGLP_23	367957	368826	rfbA	0.0	Capsule	Immune modulation	91.15	100.00	WP_011681286
EMDINGLP_23	47339	48996	fbp54	0.0	FBPs	Adherence	90.90	99.88	WP_011227179
EMDINGLP_23	152817	153548	STR_RS05260	0.0	Capsule	Immune modulation	90.57	100.00	WP_011227248
EMDINGLP_54	21497	22507	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
EMDINGLP_23	550703	552006	eno	0.0	Streptococcal enolase	Exoenzyme	88.40	99.54	WP_000022832
EMDINGLP_14	125	964	cbpD	0.0	Autolysin	Exoenzyme	87.99	99.88	WP_011226733
EMDINGLP_23	152116	152808	STR_RS05255	0.0	Capsule	Immune modulation	87.90	99.86	WP_011227247
EMDINGLP_23	152116	152808	STU_RS14640	0.0	Capsule	Immune modulation	87.90	99.86	WP_011226047
EMDINGLP_23	152116	152808	STER_RS05310	0.0	Capsule	Immune modulation	87.61	99.86	WP_011681175
EMDINGLP_8	86167	86928	srtA	0.0	Sortase A	Exoenzyme	83.90	99.74	-
EMDINGLP_15	218300	219583	tig/ropA	0.0	Trigger factor	Stress survival	80.93	99.53	WP_000107753
EMDINGLP_23	141143	141726	SPD_RS01775	3.34e-157	Capsule	Immune modulation	84.10	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
EMDINGLP_8	78039	76966	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
EMDINGLP_8	89617	90591	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.00	99.09	AAK75326
EMDINGLP_61	47029	49335	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
EMDINGLP_29	83236	84717	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
EMDINGLP_8	58987	56741	metE	0.0	methionine biosynthesis enzymes	93.19	100.00	AAK74738
EMDINGLP_38	9366	10334	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
EMDINGLP_19	15427	14456	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
EMDINGLP_29	7049	486	PrtA	0.0	serine protease	90.14	101.96	ABJ55268
EMDINGLP_23	395693	393963	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.78	100.00	AAK34199
EMDINGLP_44	95324	96475	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
EMDINGLP_48	11945	13933	uvrB	0.0	excinuclease ABC, B subunit	89.29	100.00	AE014259_2
EMDINGLP_67	108533	107055	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
EMDINGLP_23	552006	550705	Eno	0.0	enolase	86.44	99.77	ABP90468
EMDINGLP_67	92749	90857	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
EMDINGLP_8	53819	55528	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
EMDINGLP_14	20320	21411	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
EMDINGLP_16	28689	29699	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
EMDINGLP_23	62777	61416	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
EMDINGLP_23	566416	565526	bglB	8.01e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
EMDINGLP_8	13817	14767	SP_0676	2.57e-170	transcription facot	81.39	98.45	AAK74821
EMDINGLP_8	56551	55694	metF	3.91e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
EMDINGLP_29	25155	24484	rr01	2.51e-127	response regulator	84.82	99.56	CAB54566
EMDINGLP_8	49085	48414	ciaR	8.67e-126	two component system response regulator	86.16	99.12	AIK75708
EMDINGLP_23	198026	197322	covR	9.09e-126	responder protein	85.11	100.00	AAK71319
EMDINGLP_8	49085	48417	CiaR	1.60e-125	two-component response regulator	87.44	99.55	AAK74935
EMDINGLP_15	53637	52951	CovR	4.85e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
EMDINGLP_23	198026	197322	walR	1.67e-119	DNA-binding response regulator	81.70	100.00	ANC99504
EMDINGLP_14	21584	21979	SpxA2	2.19e-76	transcriptional regulator	91.67	100.00	ERL21461
EMDINGLP_23	74235	74636	SpxA1	1.18e-69	transcriptional regulator	82.84	100.00	ERL19273
EMDINGLP_35	11906	12319	GrpE	3.29e-68	protein grpE	81.16	80.59	ABP89267
EMDINGLP_15	30423	30136	spr0479	4.69e-48	essential gene	85.42	98.97	AAK99283
EMDINGLP_20	31793	32047	spr1327	1.45e-44	essential gene	90.59	100.00	AAL00131
EMDINGLP_67	30734	30997	spr0175	6.94e-43	pathogenitcity related	85.23	100.00	AAK98979
EMDINGLP_67	31558	31824	spr0177	1.54e-41	essential gene	83.15	88.12	AAK98981
EMDINGLP_15	218133	217642	RopE (M5005_Spy_1611)	1.07e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
EMDINGLP_61	47029	49329	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
EMDINGLP_16	65378	64359	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451