Genome ID：GCA_019449675.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	23	33	40.22

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HOCMNKEB_37	179012	179881	rfbA	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681286
HOCMNKEB_37	178419	179012	STER_RS06030	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
HOCMNKEB_11	12972	14630	fbp54	0.0	FBPs	Adherence	99.94	100.00	WP_011227179
HOCMNKEB_37	178419	179012	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
HOCMNKEB_20	96516	97775	STER_RS07100	0.0	Capsule	Immune modulation	99.76	100.00	WP_011681445
HOCMNKEB_37	178419	179012	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
HOCMNKEB_12	1362	2201	cbpD	0.0	Autolysin	Exoenzyme	99.52	100.00	WP_011226733
HOCMNKEB_20	95543	96519	STER_RS07095	0.0	Capsule	Immune modulation	99.39	99.90	WP_011681444
HOCMNKEB_15	52160	52950	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	99.24	100.00	-
HOCMNKEB_20	94557	95525	STER_RS07090	0.0	Capsule	Immune modulation	99.17	100.00	WP_011681443
HOCMNKEB_14	5055	5786	STER_RS05315	0.0	Capsule	Immune modulation	98.50	100.00	WP_011681176
HOCMNKEB_30	3373	4788	STER_RS05250	0.0	Capsule	Immune modulation	98.38	100.00	WP_011681165
HOCMNKEB_14	5787	7241	STR_RS05265	0.0	Capsule	Immune modulation	98.35	100.00	WP_041827043
HOCMNKEB_14	5055	5786	STR_RS05260	0.0	Capsule	Immune modulation	98.09	100.00	WP_011227248
HOCMNKEB_20	93840	94555	STER_RS07085	0.0	Capsule	Immune modulation	98.05	99.86	WP_011681442
HOCMNKEB_14	5787	7241	STU_RS14650	0.0	Capsule	Immune modulation	98.01	100.00	WP_011226049
HOCMNKEB_14	5055	5786	STU_RS14645	0.0	Capsule	Immune modulation	97.95	100.00	WP_011226048
HOCMNKEB_14	3604	4344	STU_RS14635	0.0	Capsule	Immune modulation	97.71	100.00	WP_011226046
HOCMNKEB_14	4354	5046	STR_RS05255	0.0	Capsule	Immune modulation	97.69	100.00	WP_011227247
HOCMNKEB_14	4354	5046	STU_RS14640	0.0	Capsule	Immune modulation	97.69	100.00	WP_011226047
HOCMNKEB_16	14648	15409	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
HOCMNKEB_14	3604	4344	STER_RS05305	0.0	Capsule	Immune modulation	97.57	100.00	WP_011681174
HOCMNKEB_14	3609	4344	STR_RS05250	0.0	Capsule	Immune modulation	97.28	98.13	WP_011227246
HOCMNKEB_20	92724	93494	STER_RS07075	0.0	Capsule	Immune modulation	97.15	99.10	WP_011681440
HOCMNKEB_14	5787	7241	STER_RS05320	0.0	Capsule	Immune modulation	97.12	99.79	WP_011681177
HOCMNKEB_20	97894	98745	rfbD	0.0	Capsule	Immune modulation	96.36	100.00	WP_014621820
HOCMNKEB_14	2180	3547	STU_RS14630	0.0	Capsule	Immune modulation	95.32	100.00	WP_011226045
HOCMNKEB_14	2182	3547	STER_RS05300	0.0	Capsule	Immune modulation	93.27	99.85	WP_011681173
HOCMNKEB_14	4354	5046	STER_RS05310	0.0	Capsule	Immune modulation	91.34	100.00	WP_011681175
HOCMNKEB_41	97889	99192	eno	0.0	Streptococcal enolase	Exoenzyme	88.10	99.46	WP_000022832
HOCMNKEB_25	9178	10188	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.55	99.90	WP_002986042
HOCMNKEB_37	7466	8749	tig/ropA	0.0	Trigger factor	Stress survival	80.65	99.77	WP_000107753
HOCMNKEB_37	176944	177990	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
HOCMNKEB_30	1005	1591	SPD_RS01775	5.80e-144	Capsule	Immune modulation	82.48	96.70	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HOCMNKEB_16	18096	19079	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
HOCMNKEB_4	40225	41298	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
HOCMNKEB_21	137790	140093	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
HOCMNKEB_41	14213	15181	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
HOCMNKEB_18	39863	41344	SPD_0310	0.0	UPF0371 protein SPD_0310	92.11	100.00	ABJ54480
HOCMNKEB_5	5519	7765	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
HOCMNKEB_12	33578	34570	recA	0.0	DNA recombination and repair	91.24	85.31	AAL00560
HOCMNKEB_1	4625	5596	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
HOCMNKEB_21	24119	22968	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
HOCMNKEB_20	111994	110006	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
HOCMNKEB_16	1901	171	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.04	100.00	AAK34199
HOCMNKEB_29	101285	99807	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
HOCMNKEB_41	97889	99190	Eno	0.0	enolase	86.21	99.77	ABP90468
HOCMNKEB_29	86097	84205	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
HOCMNKEB_5	10690	8981	PGM	0.0	phosphoglucomutase	83.89	99.65	ACH87041
HOCMNKEB_27	20110	21120	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
HOCMNKEB_13	19816	18455	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
HOCMNKEB_28	27171	25279	PepO	0.0	endopeptidase	80.03	100.00	ABF32980
HOCMNKEB_41	83454	84344	bglB	7.10e-180	putative phospho--glucosidase	88.89	99.66	AAK33487
HOCMNKEB_9	11847	10912	SP_0676	1.73e-169	transcription facot	81.73	96.89	AAK74821
HOCMNKEB_5	7957	8814	metF	4.10e-166	methionine biosynthesis enzymes	86.01	99.31	AAK74739
HOCMNKEB_15	24473	23769	covR	1.83e-131	responder protein	84.68	100.00	AAK71319
HOCMNKEB_18	11769	11098	rr01	8.53e-126	response regulator	83.93	99.56	CAB54566
HOCMNKEB_15	24473	23769	walR	1.31e-121	DNA-binding response regulator	80.85	100.00	ANC99504
HOCMNKEB_5	14647	15315	CiaR	1.80e-119	two-component response regulator	84.31	99.55	AAK74935
HOCMNKEB_37	160518	161204	CovR	1.08e-118	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
HOCMNKEB_5	14647	15318	ciaR	1.77e-117	two component system response regulator	82.14	99.12	AIK75708
HOCMNKEB_12	34882	35277	SpxA2	7.06e-76	transcriptional regulator	90.91	100.00	ERL21461
HOCMNKEB_13	31165	31566	SpxA1	1.74e-67	transcriptional regulator	80.60	100.00	ERL19273
HOCMNKEB_38	13229	13516	spr0479	2.96e-49	essential gene	86.46	98.97	AAK99283
HOCMNKEB_39	133508	133762	spr1327	2.36e-45	essential gene	95.29	100.00	AAL00131
HOCMNKEB_29	43519	43782	spr0175	1.91e-41	pathogenitcity related	82.95	100.00	AAK98979
HOCMNKEB_29	44322	44612	spr0177	3.64e-37	essential gene	81.00	98.02	AAK98981
HOCMNKEB_37	8907	9407	RopE (M5005_Spy_1611)	5.29e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
HOCMNKEB_21	137790	140087	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
HOCMNKEB_28	12767	11748	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	95.88	100.00	ABJ55451