Genome ID：GCA_019450035.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	23	33	40.22

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
EMADLBLA_9	53598	54467	rfbA	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681286
EMADLBLA_9	53005	53598	STER_RS06030	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
EMADLBLA_11	9420	10229	STU_RS16245	0.0	Capsule	Immune modulation	99.88	100.00	WP_002948020
EMADLBLA_9	53005	53598	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
EMADLBLA_9	53005	53598	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
EMADLBLA_6	13094	14752	fbp54	0.0	FBPs	Adherence	99.64	100.00	WP_011227179
EMADLBLA_11	7140	8195	STU_RS16235	0.0	Capsule	Immune modulation	99.62	100.00	WP_002948022
EMADLBLA_12	21208	22047	cbpD	0.0	Autolysin	Exoenzyme	99.52	100.00	WP_011226733
EMADLBLA_8	6012	6743	STER_RS05315	0.0	Capsule	Immune modulation	99.32	100.00	WP_011681176
EMADLBLA_11	8215	9420	STU_RS16240	0.0	Capsule	Immune modulation	99.25	100.00	WP_011226326
EMADLBLA_11	11166	12314	STU_RS16255	0.0	Capsule	Immune modulation	99.22	100.00	WP_041828290
EMADLBLA_11	10213	11169	STU_RS16250	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226328
EMADLBLA_11	5361	7143	STU_RS16230	0.0	Capsule	Immune modulation	99.10	99.89	WP_011226325
EMADLBLA_8	6012	6743	STU_RS14645	0.0	Capsule	Immune modulation	98.77	100.00	WP_011226048
EMADLBLA_8	6012	6743	STR_RS05260	0.0	Capsule	Immune modulation	98.63	100.00	WP_011227248
EMADLBLA_8	72880	73673	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.36	100.25	-
EMADLBLA_8	6744	8204	STER_RS05320	0.0	Capsule	Immune modulation	98.29	100.00	WP_011681177
EMADLBLA_9	88369	89130	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
EMADLBLA_8	5311	6003	STU_RS14640	0.0	Capsule	Immune modulation	97.55	100.00	WP_011226047
EMADLBLA_11	13738	14589	rfbD	0.0	Capsule	Immune modulation	97.30	100.00	WP_014621820
EMADLBLA_8	5311	6003	STR_RS05255	0.0	Capsule	Immune modulation	97.26	100.00	WP_011227247
EMADLBLA_8	4561	5301	STER_RS05305	0.0	Capsule	Immune modulation	97.03	100.00	WP_011681174
EMADLBLA_8	4561	5301	STU_RS14635	0.0	Capsule	Immune modulation	96.90	100.00	WP_011226046
EMADLBLA_8	6744	8204	STU_RS14650	0.0	Capsule	Immune modulation	96.85	100.21	WP_011226049
EMADLBLA_8	4566	5301	STR_RS05250	0.0	Capsule	Immune modulation	96.47	98.13	WP_011227246
EMADLBLA_8	6744	8204	STR_RS05265	0.0	Capsule	Immune modulation	95.89	100.21	WP_041827043
EMADLBLA_8	3137	4504	STU_RS14630	0.0	Capsule	Immune modulation	95.11	99.93	WP_011226045
EMADLBLA_8	3139	4504	STER_RS05300	0.0	Capsule	Immune modulation	94.66	99.78	WP_011681173
EMADLBLA_8	5311	6003	STER_RS05310	0.0	Capsule	Immune modulation	90.62	100.00	WP_011681175
EMADLBLA_25	229201	230504	eno	0.0	Streptococcal enolase	Exoenzyme	88.10	99.46	WP_000022832
EMADLBLA_13	123	1133	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.46	99.80	WP_002986042
EMADLBLA_23	9808	11091	tig/ropA	0.0	Trigger factor	Stress survival	80.73	99.77	WP_000107753
EMADLBLA_9	51530	52576	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
EMADLBLA_7	1313	1896	SPD_RS01775	5.10e-149	Capsule	Immune modulation	83.08	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
EMADLBLA_9	91817	92800	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
EMADLBLA_26	27718	28791	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
EMADLBLA_11	185461	187764	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
EMADLBLA_25	146971	147939	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
EMADLBLA_9	162896	164377	SPD_0310	0.0	UPF0371 protein SPD_0310	92.31	100.00	ABJ54480
EMADLBLA_26	48244	50490	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
EMADLBLA_12	40839	41837	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
EMADLBLA_12	4726	5697	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
EMADLBLA_11	64240	63089	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
EMADLBLA_11	27761	25773	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
EMADLBLA_9	75618	73888	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.39	100.00	AAK34199
EMADLBLA_18	27051	25573	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
EMADLBLA_25	229201	230502	Eno	0.0	enolase	86.21	99.77	ABP90468
EMADLBLA_18	12314	10422	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
EMADLBLA_26	53415	51706	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
EMADLBLA_15	19144	20154	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
EMADLBLA_6	40039	38678	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
EMADLBLA_16	48989	47097	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
EMADLBLA_25	214765	215655	bglB	2.27e-179	putative phospho--glucosidase	88.89	99.66	AAK33487
EMADLBLA_5	11946	11008	SP_0676	7.02e-169	transcription facot	81.15	97.20	AAK74821
EMADLBLA_26	50682	51539	metF	8.15e-166	methionine biosynthesis enzymes	86.01	99.31	AAK74739
EMADLBLA_8	45045	44341	covR	1.76e-132	responder protein	85.53	100.00	AAK71319
EMADLBLA_9	143916	143245	rr01	3.91e-125	response regulator	83.93	99.56	CAB54566
EMADLBLA_26	57370	58038	CiaR	2.79e-124	two-component response regulator	86.10	99.55	AAK74935
EMADLBLA_8	45045	44341	walR	7.43e-123	DNA-binding response regulator	82.13	100.00	ANC99504
EMADLBLA_26	57370	58041	ciaR	3.78e-122	two component system response regulator	83.93	99.12	AIK75708
EMADLBLA_23	164231	164917	CovR	3.54e-119	serves to repress GAS virulence factor-encoding genes	81.22	100.00	ACE75886
EMADLBLA_12	42113	42487	SpxA2	2.66e-71	transcriptional regulator	91.20	94.70	ERL21461
EMADLBLA_6	51457	51858	SpxA1	2.14e-67	transcriptional regulator	80.60	100.00	ERL19273
EMADLBLA_23	186623	186910	spr0479	1.63e-48	essential gene	86.46	98.97	AAK99283
EMADLBLA_25	106771	107025	spr1327	4.71e-45	essential gene	95.29	100.00	AAL00131
EMADLBLA_17	15839	16102	spr0175	1.46e-42	pathogenitcity related	84.09	100.00	AAK98979
EMADLBLA_17	16666	16932	spr0177	3.19e-34	essential gene	84.27	88.12	AAK98981
EMADLBLA_23	11249	11749	RopE (M5005_Spy_1611)	5.64e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
EMADLBLA_11	185461	187758	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
EMADLBLA_16	34530	33511	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451