Genome ID：GCA_019450055.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
1	23	32	39.42

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
FIHJBCDE_63	1169	3109	tet(S)	ARO:3000192	tet(S)	99.84	100.78	L09756.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
FIHJBCDE_63	1184	3109	tet(S)	Doxycycline, Tetracycline, Minocycline	100.00	100.00	L09756

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
FIHJBCDE_63	1184	3106	tet(S)	tetracycline resistance ribosomal protection protein Tet(S)	EXACTX	100.00	100.00	WP_000691722.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
FIHJBCDE_39	16358	17167	STU_RS16245	0.0	Capsule	Immune modulation	99.75	100.00	WP_002948020
FIHJBCDE_18	13458	15116	fbp54	0.0	FBPs	Adherence	99.34	100.00	WP_011227179
FIHJBCDE_39	17151	18107	STU_RS16250	0.0	Capsule	Immune modulation	99.27	100.00	WP_011226328
FIHJBCDE_24	6211	7671	STER_RS05320	0.0	Capsule	Immune modulation	99.25	100.00	WP_011681177
FIHJBCDE_39	15153	16358	STU_RS16240	0.0	Capsule	Immune modulation	99.25	100.00	WP_011226326
FIHJBCDE_39	18104	19252	STU_RS16255	0.0	Capsule	Immune modulation	99.22	100.00	WP_041828290
FIHJBCDE_39	12299	14081	STU_RS16230	0.0	Capsule	Immune modulation	99.22	99.89	WP_011226325
FIHJBCDE_27	2891	3484	STR_RS05880	0.0	Capsule	Immune modulation	99.16	100.00	WP_011226149
FIHJBCDE_39	14078	15133	STU_RS16235	0.0	Capsule	Immune modulation	99.15	100.00	WP_002948022
FIHJBCDE_40	228	1079	rfbD	0.0	Capsule	Immune modulation	99.06	100.00	WP_014621820
FIHJBCDE_27	2891	3484	STER_RS06030	0.0	Capsule	Immune modulation	98.99	100.00	WP_011226149
FIHJBCDE_27	2891	3484	STU_RS15260	0.0	Capsule	Immune modulation	98.99	100.00	WP_011226149
FIHJBCDE_27	3484	4353	rfbA	0.0	Capsule	Immune modulation	98.97	100.00	WP_011681286
FIHJBCDE_27	37446	38207	srtA	0.0	Sortase A	Exoenzyme	98.56	100.00	-
FIHJBCDE_24	5479	6210	STER_RS05315	0.0	Capsule	Immune modulation	98.50	100.00	WP_011681176
FIHJBCDE_12	228	1067	cbpD	0.0	Autolysin	Exoenzyme	98.33	100.00	WP_011226733
FIHJBCDE_24	5479	6210	STU_RS14645	0.0	Capsule	Immune modulation	97.95	100.00	WP_011226048
FIHJBCDE_24	5479	6210	STR_RS05260	0.0	Capsule	Immune modulation	97.81	100.00	WP_011227248
FIHJBCDE_24	72160	72948	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	97.35	99.62	-
FIHJBCDE_24	6211	7671	STU_RS14650	0.0	Capsule	Immune modulation	96.99	100.21	WP_011226049
FIHJBCDE_24	4028	4768	STER_RS05305	0.0	Capsule	Immune modulation	96.76	100.00	WP_011681174
FIHJBCDE_24	6211	7671	STR_RS05265	0.0	Capsule	Immune modulation	96.58	100.21	WP_041827043
FIHJBCDE_24	4028	4768	STU_RS14635	0.0	Capsule	Immune modulation	96.36	100.00	WP_011226046
FIHJBCDE_24	4033	4768	STR_RS05250	0.0	Capsule	Immune modulation	96.20	98.13	WP_011227246
FIHJBCDE_24	4778	5470	STU_RS14640	0.0	Capsule	Immune modulation	95.96	100.00	WP_011226047
FIHJBCDE_24	4778	5470	STR_RS05255	0.0	Capsule	Immune modulation	95.67	100.00	WP_011227247
FIHJBCDE_24	2606	3971	STER_RS05300	0.0	Capsule	Immune modulation	95.39	99.85	WP_011681173
FIHJBCDE_24	2604	3971	STU_RS14630	0.0	Capsule	Immune modulation	94.15	100.00	WP_011226045
FIHJBCDE_24	4778	5470	STER_RS05310	0.0	Capsule	Immune modulation	92.06	100.00	WP_011681175
FIHJBCDE_8	36116	37419	eno	0.0	Streptococcal enolase	Exoenzyme	88.09	99.54	WP_000022832
FIHJBCDE_51	570	1580	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.35	99.90	WP_002986042
FIHJBCDE_45	2769	4052	tig/ropA	0.0	Trigger factor	Stress survival	80.65	99.77	WP_000107753
FIHJBCDE_27	1415	2461	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
FIHJBCDE_22	1256	1839	SPD_RS01775	1.08e-145	Capsule	Immune modulation	82.73	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
FIHJBCDE_10	71803	72876	MntE	0.0	manganese homeostasis	94.97	99.72	ABF32167
FIHJBCDE_27	40894	41877	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
FIHJBCDE_7	13308	14276	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
FIHJBCDE_30	6916	8397	SPD_0310	0.0	UPF0371 protein SPD_0310	92.51	100.00	ABJ54480
FIHJBCDE_47	15917	18220	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.45	99.22	AAK74619
FIHJBCDE_11	6356	8602	metE	0.0	methionine biosynthesis enzymes	91.86	100.00	AAK74738
FIHJBCDE_12	30965	31963	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
FIHJBCDE_1	4647	5618	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
FIHJBCDE_41	7493	6342	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
FIHJBCDE_40	14574	12586	uvrB	0.0	excinuclease ABC, B subunit	89.14	100.00	AE014259_2
FIHJBCDE_27	25501	23771	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.87	100.00	AAK34199
FIHJBCDE_58	27572	26094	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
FIHJBCDE_8	36116	37417	Eno	0.0	enolase	85.98	99.77	ABP90468
FIHJBCDE_58	12371	10479	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
FIHJBCDE_11	11527	9818	PGM	0.0	phosphoglucomutase	83.71	99.65	ACH87041
FIHJBCDE_53	61045	62055	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
FIHJBCDE_20	17014	15653	mnmE	0.0	central tRNA-modifying GTPase	81.80	99.56	ABP90420
FIHJBCDE_8	21678	22568	bglB	4.20e-180	putative phospho--glucosidase	88.89	99.66	AAK33487
FIHJBCDE_17	14024	13086	SP_0676	7.66e-169	transcription facot	81.15	97.20	AAK74821
FIHJBCDE_11	8794	9651	metF	4.88e-166	methionine biosynthesis enzymes	85.66	99.31	AAK74739
FIHJBCDE_24	44473	43769	covR	1.75e-132	responder protein	85.53	100.00	AAK71319
FIHJBCDE_29	10774	10103	rr01	5.06e-127	response regulator	84.38	99.56	CAB54566
FIHJBCDE_11	15481	16149	CiaR	5.49e-126	two-component response regulator	87.44	99.55	AAK74935
FIHJBCDE_11	15481	16152	ciaR	5.89e-124	two component system response regulator	85.27	99.12	AIK75708
FIHJBCDE_24	44473	43769	walR	7.36e-123	DNA-binding response regulator	82.13	100.00	ANC99504
FIHJBCDE_72	17845	18531	CovR	4.19e-120	serves to repress GAS virulence factor-encoding genes	81.22	100.00	ACE75886
FIHJBCDE_12	32239	32634	SpxA2	6.55e-76	transcriptional regulator	90.91	100.00	ERL21461
FIHJBCDE_20	28499	28900	SpxA1	1.36e-67	transcriptional regulator	80.60	100.00	ERL19273
FIHJBCDE_2	13210	13497	spr0479	1.19e-48	essential gene	84.38	98.97	AAK99283
FIHJBCDE_5	10981	11235	spr1327	8.32e-46	essential gene	95.29	100.00	AAL00131
FIHJBCDE_57	13024	13287	spr0175	1.73e-42	pathogenitcity related	84.09	100.00	AAK98979
FIHJBCDE_57	13851	14117	spr0177	3.05e-34	essential gene	84.27	88.12	AAK98981
FIHJBCDE_45	4210	4710	RopE (M5005_Spy_1611)	4.39e-77	probable DNA-directed RNA polymerase subunit delta	82.04	87.43	AAK34603
FIHJBCDE_47	15941	18214	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.16	97.06	MYN69560
FIHJBCDE_53	96908	95889	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451