Genome ID：GCA_019731335.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	17	34	38.07

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
CMBEKOCF_33	43048	44967	tet(M)	ARO:3000186	tet(M)	91.39	100.00	AB039845.1
CMBEKOCF_33	41386	42123	ErmB	ARO:3000375	ErmB	97.96	98.79	AF242872.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
CMBEKOCF_33	41386	42123	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	U86375
CMBEKOCF_33	43048	44967	tet(M)	Doxycycline, Tetracycline, Minocycline	94.90	99.95	X04388

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
CMBEKOCF_33	41389	42123	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038790.1
CMBEKOCF_33	43051	44967	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	BLASTX	97.81	100.00	WP_011860841.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
CMBEKOCF_13	20050	20901	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
CMBEKOCF_12	1756	2487	STER_RS05315	0.0	Capsule	Immune modulation	94.81	100.00	WP_011681176
CMBEKOCF_12	1756	2487	STU_RS14645	0.0	Capsule	Immune modulation	94.54	100.00	WP_011226048
CMBEKOCF_13	23325	24040	STER_RS07085	0.0	Capsule	Immune modulation	94.41	99.86	WP_011681442
CMBEKOCF_12	1756	2487	STR_RS05260	0.0	Capsule	Immune modulation	94.13	100.00	WP_011227248
CMBEKOCF_13	24386	25156	STER_RS07075	0.0	Capsule	Immune modulation	92.48	99.23	WP_011681440
CMBEKOCF_13	21020	22278	STER_RS07100	0.0	Capsule	Immune modulation	92.22	99.92	WP_011681445
CMBEKOCF_35	92483	93076	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
CMBEKOCF_12	295	1755	STER_RS05320	0.0	Capsule	Immune modulation	90.92	99.86	WP_011681177
CMBEKOCF_35	92483	93076	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
CMBEKOCF_35	92483	93076	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
CMBEKOCF_12	295	1755	STU_RS14650	0.0	Capsule	Immune modulation	90.78	100.00	WP_011226049
CMBEKOCF_12	112797	114454	fbp54	0.0	FBPs	Adherence	90.36	99.88	WP_011227179
CMBEKOCF_12	295	1755	STR_RS05265	0.0	Capsule	Immune modulation	89.97	100.00	WP_041827043
CMBEKOCF_12	2496	3188	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
CMBEKOCF_12	2496	3188	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
CMBEKOCF_12	2496	3188	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
CMBEKOCF_36	80059	81362	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
CMBEKOCF_33	57267	58106	cbpD	0.0	Autolysin	Exoenzyme	87.87	99.88	WP_011226733
CMBEKOCF_1	31595	32356	srtA	0.0	Sortase A	Exoenzyme	86.65	99.74	-
CMBEKOCF_18	123	1136	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
CMBEKOCF_35	91167	92213	rfbB	0.0	Capsule	Immune modulation	83.49	99.90	WP_002263087
CMBEKOCF_17	1821	3104	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753
CMBEKOCF_35	93076	93945	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
CMBEKOCF_12	3198	3868	STU_RS14635	1.43e-147	Capsule	Immune modulation	80.98	90.28	WP_011226046
CMBEKOCF_12	3198	3868	STER_RS05305	6.64e-146	Capsule	Immune modulation	80.83	90.28	WP_011681174
CMBEKOCF_12	3198	3800	STR_RS05250	6.73e-136	Capsule	Immune modulation	81.46	80.13	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
CMBEKOCF_1	35045	36019	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.31	99.09	AAK75326
CMBEKOCF_1	23463	22390	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
CMBEKOCF_23	81196	83502	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
CMBEKOCF_1	169679	171160	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
CMBEKOCF_38	82101	83069	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
CMBEKOCF_1	3922	1676	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
CMBEKOCF_6	36856	35885	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
CMBEKOCF_1	87985	81512	PrtA	0.0	serine protease	91.44	100.61	ABJ55268
CMBEKOCF_21	9593	11323	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
CMBEKOCF_13	4918	6906	uvrB	0.0	excinuclease ABC, B subunit	89.74	100.00	AE014259_2
CMBEKOCF_5	11036	9885	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
CMBEKOCF_2	7293	8771	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
CMBEKOCF_36	80059	81360	Eno	0.0	enolase	86.44	99.77	ABP90468
CMBEKOCF_2	23261	25153	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
CMBEKOCF_6	1213	122	recA	0.0	DNA recombination and repair	84.91	95.36	AAL00560
CMBEKOCF_12	239496	241205	PGM	0.0	phosphoglucomutase	84.59	99.65	ACH87041
CMBEKOCF_12	99036	100397	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
CMBEKOCF_33	165277	166287	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
CMBEKOCF_36	65645	66535	bglB	1.24e-177	putative phospho--glucosidase	87.20	99.66	AAK33487
CMBEKOCF_1	1486	629	metF	1.05e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
CMBEKOCF_12	197956	198894	SP_0676	1.65e-168	transcription facot	81.47	97.20	AAK74821
CMBEKOCF_10	32221	31517	covR	2.71e-128	responder protein	85.96	100.00	AAK71319
CMBEKOCF_1	105965	105294	rr01	5.18e-127	response regulator	84.82	99.56	CAB54566
CMBEKOCF_12	234830	234159	ciaR	2.31e-125	two component system response regulator	86.16	99.12	AIK75708
CMBEKOCF_12	234830	234162	CiaR	4.27e-125	two-component response regulator	87.44	99.55	AAK74935
CMBEKOCF_4	17587	18273	CovR	4.51e-121	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
CMBEKOCF_10	32221	31517	walR	1.63e-120	DNA-binding response regulator	81.70	100.00	ANC99504
CMBEKOCF_31	610	215	SpxA2	2.98e-85	transcriptional regulator	91.67	100.00	ERL21461
CMBEKOCF_12	87578	87177	SpxA1	1.54e-69	transcriptional regulator	82.09	100.00	ERL19273
CMBEKOCF_7	33439	33852	GrpE	3.09e-68	protein grpE	81.88	80.59	ABP89267
CMBEKOCF_4	40789	41076	spr0479	1.43e-48	essential gene	85.42	98.97	AAK99283
CMBEKOCF_38	31684	31938	spr1327	2.91e-46	essential gene	94.12	100.00	AAL00131
CMBEKOCF_2	54440	54177	spr0175	3.45e-43	pathogenitcity related	85.23	100.00	AAK98979
CMBEKOCF_2	53615	53349	spr0177	7.67e-42	essential gene	83.15	88.12	AAK98981
CMBEKOCF_17	3271	3762	RopE (M5005_Spy_1611)	7.13e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
CMBEKOCF_23	81196	83496	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
CMBEKOCF_33	201692	200673	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451
CMBEKOCF_12	133712	133173	pnuC	1.36e-92	NAD salvage pathway importer	82.78	66.91	AAK75931