Genome ID：GCA_020075945.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	35	33	48.10

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
EKBFFMEE_62	60320	61189	rfbA	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681286
EKBFFMEE_58	231	1646	STER_RS05250	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681165
EKBFFMEE_34	705	1685	STER_RS05260	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681166
EKBFFMEE_34	1678	2862	STER_RS05265	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681167
EKBFFMEE_34	2879	3931	STER_RS05270	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681168
EKBFFMEE_34	3946	4854	STER_RS05275	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681169
EKBFFMEE_34	4875	5936	STER_RS05280	0.0	Capsule	Immune modulation	100.00	100.00	WP_202964935
EKBFFMEE_34	5973	6464	STER_RS05285	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681171
EKBFFMEE_34	6476	6952	STER_RS05290	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681172
EKBFFMEE_34	9132	9872	STER_RS05305	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681174
EKBFFMEE_34	9882	10574	STER_RS05310	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681175
EKBFFMEE_34	10583	11314	STER_RS05315	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681176
EKBFFMEE_34	11315	12775	STER_RS05320	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681177
EKBFFMEE_62	61189	61782	STER_RS06030	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
EKBFFMEE_12	10825	12570	STER_RS07045	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681434
EKBFFMEE_12	12572	14272	STER_RS07050	0.0	Capsule	Immune modulation	100.00	100.00	WP_041827753
EKBFFMEE_12	14290	15492	STER_RS07055	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681436
EKBFFMEE_12	15492	16298	STER_RS07060	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681437
EKBFFMEE_12	16298	17239	STER_RS07065	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681438
EKBFFMEE_12	17236	18384	STER_RS07070	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681439
EKBFFMEE_12	18503	19279	STER_RS07075	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681440
EKBFFMEE_12	19625	20341	STER_RS07085	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681442
EKBFFMEE_12	20342	21310	STER_RS07090	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681443
EKBFFMEE_12	21328	22305	STER_RS07095	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681444
EKBFFMEE_12	22302	23561	STER_RS07100	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681445
EKBFFMEE_34	7708	9075	STER_RS05300	0.0	Capsule	Immune modulation	99.85	100.00	WP_011681173
EKBFFMEE_62	61189	61782	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
EKBFFMEE_12	12572	14272	STR_RS06890	0.0	Capsule	Immune modulation	99.71	100.00	WP_041827077
EKBFFMEE_62	61189	61782	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
EKBFFMEE_25	2393	4051	fbp54	0.0	FBPs	Adherence	99.64	100.00	WP_011227179
EKBFFMEE_12	15492	16298	STR_RS06900	0.0	Capsule	Immune modulation	99.50	100.00	WP_011227429
EKBFFMEE_12	16298	17239	STR_RS06905	0.0	Capsule	Immune modulation	99.47	100.00	WP_011227430
EKBFFMEE_12	14290	15492	STR_RS06895	0.0	Capsule	Immune modulation	99.42	100.00	WP_011227428
EKBFFMEE_12	17236	18384	STR_RS06910	0.0	Capsule	Immune modulation	99.22	100.00	WP_011227431
EKBFFMEE_16	2124	3092	cbpD	0.0	Autolysin	Exoenzyme	98.86	100.00	WP_082302295
EKBFFMEE_34	85907	86697	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.74	100.00	-
EKBFFMEE_34	9137	9872	STR_RS05250	0.0	Capsule	Immune modulation	98.50	98.13	WP_011227246
EKBFFMEE_34	9132	9872	STU_RS14635	0.0	Capsule	Immune modulation	98.25	100.00	WP_011226046
EKBFFMEE_34	10583	11314	STR_RS05260	0.0	Capsule	Immune modulation	98.22	100.00	WP_011227248
EKBFFMEE_12	10825	12570	STR_RS06885	0.0	Capsule	Immune modulation	98.22	100.00	WP_011227426
EKBFFMEE_34	10583	11314	STU_RS14645	0.0	Capsule	Immune modulation	98.09	100.00	WP_011226048
EKBFFMEE_62	25659	26420	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
EKBFFMEE_34	11315	12775	STU_RS14650	0.0	Capsule	Immune modulation	97.47	100.21	WP_011226049
EKBFFMEE_34	11315	12775	STR_RS05265	0.0	Capsule	Immune modulation	96.92	100.21	WP_041827043
EKBFFMEE_12	23680	24531	rfbD	0.0	Capsule	Immune modulation	96.83	100.00	WP_014621820
EKBFFMEE_34	7712	9075	STU_RS14630	0.0	Capsule	Immune modulation	94.94	99.71	WP_011226045
EKBFFMEE_34	9882	10574	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
EKBFFMEE_34	9882	10574	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
EKBFFMEE_23	19344	20647	eno	0.0	Streptococcal enolase	Exoenzyme	88.10	99.46	WP_000022832
EKBFFMEE_32	13387	14397	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.54	99.41	WP_002986042
EKBFFMEE_12	15492	16298	SGO_RS05020	0.0	Capsule	Immune modulation	82.90	100.00	WP_012000440
EKBFFMEE_68	59407	60690	tig/ropA	0.0	Trigger factor	Stress survival	80.73	99.77	WP_000107753
EKBFFMEE_62	62211	63257	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
EKBFFMEE_12	14755	15492	SGO_RS05025	0.0	Capsule	Immune modulation	84.96	60.29	WP_012000441

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
EKBFFMEE_62	22972	21989	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
EKBFFMEE_19	13975	12902	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
EKBFFMEE_53	63435	61132	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
EKBFFMEE_4	15173	16141	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
EKBFFMEE_10	33601	35082	SPD_0310	0.0	UPF0371 protein SPD_0310	92.51	100.00	ABJ54480
EKBFFMEE_24	11077	13323	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
EKBFFMEE_17	1941	943	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
EKBFFMEE_29	15275	14319	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.60	98.46	ABF36968
EKBFFMEE_12	72669	71518	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
EKBFFMEE_12	37570	35582	uvrB	0.0	excinuclease ABC, B subunit	89.14	100.00	AE014259_2
EKBFFMEE_62	39171	40901	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.87	100.00	AAK34199
EKBFFMEE_6	30385	28907	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
EKBFFMEE_23	19344	20645	Eno	0.0	enolase	86.21	99.77	ABP90468
EKBFFMEE_6	15650	13758	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
EKBFFMEE_24	16248	14539	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
EKBFFMEE_2	40149	39139	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
EKBFFMEE_45	22054	20693	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
EKBFFMEE_30	10285	8393	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
EKBFFMEE_23	4908	5798	bglB	2.70e-179	putative phospho--glucosidase	88.55	99.66	AAK33487
EKBFFMEE_8	4804	3866	SP_0676	1.89e-169	transcription facot	81.47	97.20	AAK74821
EKBFFMEE_24	13515	14372	metF	1.47e-166	methionine biosynthesis enzymes	86.36	99.31	AAK74739
EKBFFMEE_34	49598	48894	covR	2.07e-132	responder protein	85.53	100.00	AAK71319
EKBFFMEE_10	8994	8323	rr01	6.51e-126	response regulator	83.93	99.56	CAB54566
EKBFFMEE_34	49598	48894	walR	8.72e-123	DNA-binding response regulator	82.13	100.00	ANC99504
EKBFFMEE_50	1892	2560	CiaR	7.31e-122	two-component response regulator	84.31	99.55	AAK74935
EKBFFMEE_50	1892	2563	ciaR	9.62e-120	two component system response regulator	82.14	99.12	AIK75708
EKBFFMEE_14	24031	24717	CovR	1.70e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
EKBFFMEE_17	667	293	SpxA2	1.34e-71	transcriptional regulator	91.20	94.70	ERL21461
EKBFFMEE_45	33417	33818	SpxA1	1.77e-67	transcriptional regulator	80.60	100.00	ERL19273
EKBFFMEE_13	13030	13317	spr0479	2.95e-49	essential gene	86.46	98.97	AAK99283
EKBFFMEE_11	6517	6263	spr1327	4.16e-45	essential gene	94.12	100.00	AAL00131
EKBFFMEE_33	1215	952	spr0175	5.34e-43	pathogenitcity related	84.09	100.00	AAK98979
EKBFFMEE_33	388	122	spr0177	1.16e-34	essential gene	84.27	88.12	AAK98981
EKBFFMEE_68	59249	58749	RopE (M5005_Spy_1611)	1.74e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
EKBFFMEE_53	63435	61138	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
EKBFFMEE_2	4288	5307	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451