Genome ID：GCA_020075965.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	35	33	48.10

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
ICPEPJGA_29	9521	10390	rfbA	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681286
ICPEPJGA_47	88494	89909	STER_RS05250	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681165
ICPEPJGA_47	86313	87293	STER_RS05260	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681166
ICPEPJGA_47	85136	86320	STER_RS05265	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681167
ICPEPJGA_47	84067	85119	STER_RS05270	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681168
ICPEPJGA_47	83144	84052	STER_RS05275	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681169
ICPEPJGA_47	82062	83123	STER_RS05280	0.0	Capsule	Immune modulation	100.00	100.00	WP_202964935
ICPEPJGA_47	81534	82025	STER_RS05285	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681171
ICPEPJGA_47	81046	81522	STER_RS05290	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681172
ICPEPJGA_47	78126	78866	STER_RS05305	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681174
ICPEPJGA_47	77424	78116	STER_RS05310	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681175
ICPEPJGA_47	76684	77415	STER_RS05315	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681176
ICPEPJGA_47	75223	76683	STER_RS05320	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681177
ICPEPJGA_29	8928	9521	STER_RS06030	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
ICPEPJGA_45	105038	106783	STER_RS07045	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681434
ICPEPJGA_45	103336	105036	STER_RS07050	0.0	Capsule	Immune modulation	100.00	100.00	WP_041827753
ICPEPJGA_45	102116	103318	STER_RS07055	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681436
ICPEPJGA_45	101310	102116	STER_RS07060	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681437
ICPEPJGA_45	100369	101310	STER_RS07065	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681438
ICPEPJGA_45	99224	100372	STER_RS07070	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681439
ICPEPJGA_45	98329	99105	STER_RS07075	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681440
ICPEPJGA_45	97267	97983	STER_RS07085	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681442
ICPEPJGA_45	96298	97266	STER_RS07090	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681443
ICPEPJGA_45	95303	96280	STER_RS07095	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681444
ICPEPJGA_45	94047	95306	STER_RS07100	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681445
ICPEPJGA_47	78923	80290	STER_RS05300	0.0	Capsule	Immune modulation	99.85	100.00	WP_011681173
ICPEPJGA_29	8928	9521	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
ICPEPJGA_45	103336	105036	STR_RS06890	0.0	Capsule	Immune modulation	99.71	100.00	WP_041827077
ICPEPJGA_29	8928	9521	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
ICPEPJGA_46	89717	91375	fbp54	0.0	FBPs	Adherence	99.64	100.00	WP_011227179
ICPEPJGA_45	101310	102116	STR_RS06900	0.0	Capsule	Immune modulation	99.50	100.00	WP_011227429
ICPEPJGA_45	100369	101310	STR_RS06905	0.0	Capsule	Immune modulation	99.47	100.00	WP_011227430
ICPEPJGA_45	102116	103318	STR_RS06895	0.0	Capsule	Immune modulation	99.42	100.00	WP_011227428
ICPEPJGA_45	99224	100372	STR_RS06910	0.0	Capsule	Immune modulation	99.22	100.00	WP_011227431
ICPEPJGA_16	7324	8292	cbpD	0.0	Autolysin	Exoenzyme	98.86	100.00	WP_082302295
ICPEPJGA_47	1301	2091	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.74	100.00	-
ICPEPJGA_47	78126	78861	STR_RS05250	0.0	Capsule	Immune modulation	98.50	98.13	WP_011227246
ICPEPJGA_47	78126	78866	STU_RS14635	0.0	Capsule	Immune modulation	98.25	100.00	WP_011226046
ICPEPJGA_47	76684	77415	STR_RS05260	0.0	Capsule	Immune modulation	98.22	100.00	WP_011227248
ICPEPJGA_45	105038	106783	STR_RS06885	0.0	Capsule	Immune modulation	98.22	100.00	WP_011227426
ICPEPJGA_47	76684	77415	STU_RS14645	0.0	Capsule	Immune modulation	98.09	100.00	WP_011226048
ICPEPJGA_29	44290	45051	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
ICPEPJGA_47	75223	76683	STU_RS14650	0.0	Capsule	Immune modulation	97.47	100.21	WP_011226049
ICPEPJGA_47	75223	76683	STR_RS05265	0.0	Capsule	Immune modulation	96.92	100.21	WP_041827043
ICPEPJGA_45	93077	93928	rfbD	0.0	Capsule	Immune modulation	96.83	100.00	WP_014621820
ICPEPJGA_47	78923	80286	STU_RS14630	0.0	Capsule	Immune modulation	94.94	99.71	WP_011226045
ICPEPJGA_47	77424	78116	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
ICPEPJGA_47	77424	78116	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
ICPEPJGA_38	46460	47763	eno	0.0	Streptococcal enolase	Exoenzyme	88.10	99.46	WP_000022832
ICPEPJGA_24	14294	15304	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.54	99.41	WP_002986042
ICPEPJGA_45	101310	102116	SGO_RS05020	0.0	Capsule	Immune modulation	82.90	100.00	WP_012000440
ICPEPJGA_18	159345	160628	tig/ropA	0.0	Trigger factor	Stress survival	80.73	99.77	WP_000107753
ICPEPJGA_29	7453	8499	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
ICPEPJGA_45	102116	102853	SGO_RS05025	0.0	Capsule	Immune modulation	84.96	60.29	WP_012000441

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
ICPEPJGA_29	47738	48721	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
ICPEPJGA_48	27639	28712	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
ICPEPJGA_43	57528	59831	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
ICPEPJGA_5	37294	36326	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
ICPEPJGA_29	124494	125975	SPD_0310	0.0	UPF0371 protein SPD_0310	92.51	100.00	ABJ54480
ICPEPJGA_48	59550	61796	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
ICPEPJGA_17	40292	41290	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
ICPEPJGA_17	4177	5148	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
ICPEPJGA_45	44939	46090	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
ICPEPJGA_45	80038	82026	uvrB	0.0	excinuclease ABC, B subunit	89.14	100.00	AE014259_2
ICPEPJGA_29	31539	29809	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.87	100.00	AAK34199
ICPEPJGA_4	13824	15302	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
ICPEPJGA_38	46460	47761	Eno	0.0	enolase	86.21	99.77	ABP90468
ICPEPJGA_4	28559	30451	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
ICPEPJGA_48	64721	63012	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
ICPEPJGA_1	22463	23473	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
ICPEPJGA_46	65282	66643	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
ICPEPJGA_13	37056	38948	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
ICPEPJGA_38	32024	32914	bglB	3.47e-179	putative phospho--glucosidase	88.55	99.66	AAK33487
ICPEPJGA_6	12490	11552	SP_0676	2.26e-169	transcription facot	81.47	97.20	AAK74821
ICPEPJGA_48	61988	62845	metF	5.82e-166	methionine biosynthesis enzymes	86.36	99.31	AAK74739
ICPEPJGA_47	38400	39104	covR	2.12e-132	responder protein	85.53	100.00	AAK71319
ICPEPJGA_29	99887	99216	rr01	2.21e-125	response regulator	83.93	99.56	CAB54566
ICPEPJGA_47	38400	39104	walR	8.95e-123	DNA-binding response regulator	82.13	100.00	ANC99504
ICPEPJGA_48	68676	69344	CiaR	7.70e-119	two-component response regulator	84.31	99.55	AAK74935
ICPEPJGA_18	7669	6983	CovR	8.82e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
ICPEPJGA_48	68676	69347	ciaR	7.58e-117	two component system response regulator	82.14	99.12	AIK75708
ICPEPJGA_17	41566	41940	SpxA2	2.61e-71	transcriptional regulator	91.20	94.70	ERL21461
ICPEPJGA_46	53919	53518	SpxA1	2.12e-67	transcriptional regulator	80.60	100.00	ERL19273
ICPEPJGA_20	25972	25685	spr0479	2.97e-49	essential gene	86.46	98.97	AAK99283
ICPEPJGA_19	6517	6263	spr1327	4.16e-45	essential gene	94.12	100.00	AAL00131
ICPEPJGA_35	1215	952	spr0175	1.86e-43	pathogenitcity related	84.09	100.00	AAK98979
ICPEPJGA_35	388	122	spr0177	4.02e-35	essential gene	84.27	88.12	AAK98981
ICPEPJGA_18	159187	158687	RopE (M5005_Spy_1611)	4.32e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
ICPEPJGA_43	57528	59825	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
ICPEPJGA_1	58324	57305	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451