Genome ID：GCA_020075985.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	24	33	40.80

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NONAKEBI_18	19439	20308	rfbA	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681286
NONAKEBI_18	20308	20901	STER_RS06030	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
NONAKEBI_4	16628	17437	STU_RS16245	0.0	Capsule	Immune modulation	99.88	100.00	WP_002948020
NONAKEBI_18	20308	20901	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
NONAKEBI_4	17421	18377	STU_RS16250	0.0	Capsule	Immune modulation	99.79	100.00	WP_011226328
NONAKEBI_4	18374	19522	STU_RS16255	0.0	Capsule	Immune modulation	99.74	100.00	WP_041828290
NONAKEBI_18	20308	20901	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
NONAKEBI_4	23018	23869	rfbD	0.0	Capsule	Immune modulation	99.65	100.00	WP_014621820
NONAKEBI_8	25146	26804	fbp54	0.0	FBPs	Adherence	99.58	100.00	WP_011227179
NONAKEBI_4	15423	16628	STU_RS16240	0.0	Capsule	Immune modulation	99.58	100.00	WP_011226326
NONAKEBI_4	12567	14351	STU_RS16230	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226325
NONAKEBI_4	19631	20641	STU_RS16260	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226330
NONAKEBI_4	14348	15403	STU_RS16235	0.0	Capsule	Immune modulation	99.34	100.00	WP_002948022
NONAKEBI_7	14576	15337	srtA	0.0	Sortase A	Exoenzyme	98.82	100.00	-
NONAKEBI_12	16472	17311	cbpD	0.0	Autolysin	Exoenzyme	98.69	100.00	WP_011226733
NONAKEBI_20	18709	19497	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.48	99.75	-
NONAKEBI_42	13485	14216	STU_RS14645	0.0	Capsule	Immune modulation	98.36	100.00	WP_011226048
NONAKEBI_42	13485	14216	STER_RS05315	0.0	Capsule	Immune modulation	98.09	100.00	WP_011681176
NONAKEBI_42	13485	14216	STR_RS05260	0.0	Capsule	Immune modulation	97.68	100.00	WP_011227248
NONAKEBI_4	20644	21915	STU_RS16265	0.0	Capsule	Immune modulation	97.48	99.76	WP_011226331
NONAKEBI_42	12024	13484	STER_RS05320	0.0	Capsule	Immune modulation	97.06	100.00	WP_011681177
NONAKEBI_42	14927	15667	STER_RS05305	0.0	Capsule	Immune modulation	97.03	100.00	WP_011681174
NONAKEBI_42	14927	15667	STU_RS14635	0.0	Capsule	Immune modulation	96.36	100.00	WP_011226046
NONAKEBI_42	12024	13484	STU_RS14650	0.0	Capsule	Immune modulation	96.30	100.21	WP_011226049
NONAKEBI_42	12024	13484	STR_RS05265	0.0	Capsule	Immune modulation	96.17	100.21	WP_041827043
NONAKEBI_42	14927	15662	STR_RS05250	0.0	Capsule	Immune modulation	96.06	98.13	WP_011227246
NONAKEBI_42	15724	17087	STU_RS14630	0.0	Capsule	Immune modulation	95.53	99.71	WP_011226045
NONAKEBI_42	14225	14917	STR_RS05255	0.0	Capsule	Immune modulation	95.40	99.86	WP_011227247
NONAKEBI_42	14225	14917	STU_RS14640	0.0	Capsule	Immune modulation	95.40	99.86	WP_011226047
NONAKEBI_42	15724	17091	STER_RS05300	0.0	Capsule	Immune modulation	94.52	99.93	WP_011681173
NONAKEBI_42	14225	14917	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
NONAKEBI_31	95612	96915	eno	0.0	Streptococcal enolase	Exoenzyme	88.10	99.46	WP_000022832
NONAKEBI_33	3678	4688	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.46	99.80	WP_002986042
NONAKEBI_1	4821	6104	tig/ropA	0.0	Trigger factor	Stress survival	80.73	99.77	WP_000107753
NONAKEBI_18	21330	22376	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NONAKEBI_7	18024	19007	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
NONAKEBI_19	13764	12691	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
NONAKEBI_11	15527	13224	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
NONAKEBI_31	11977	12945	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
NONAKEBI_22	51703	53184	SPD_0310	0.0	UPF0371 protein SPD_0310	92.31	100.00	ABJ54480
NONAKEBI_2	44036	41790	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
NONAKEBI_12	36102	37094	recA	0.0	DNA recombination and repair	91.24	85.31	AAL00560
NONAKEBI_12	1	957	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.60	98.46	ABF36968
NONAKEBI_11	129220	130371	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
NONAKEBI_4	38839	36851	uvrB	0.0	excinuclease ABC, B subunit	88.84	100.00	AE014259_2
NONAKEBI_7	1829	99	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.04	100.00	AAK34199
NONAKEBI_48	26986	28464	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
NONAKEBI_31	95612	96913	Eno	0.0	enolase	86.21	99.77	ABP90468
NONAKEBI_48	42175	44067	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
NONAKEBI_27	2038	329	PGM	0.0	phosphoglucomutase	84.06	99.65	ACH87041
NONAKEBI_53	60823	59813	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
NONAKEBI_42	94770	96131	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
NONAKEBI_53	10456	12348	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
NONAKEBI_31	81176	82066	bglB	3.55e-179	putative phospho--glucosidase	88.55	99.66	AAK33487
NONAKEBI_3	12340	11405	SP_0676	2.04e-169	transcription facot	81.73	96.89	AAK74821
NONAKEBI_2	41598	40741	metF	4.70e-166	methionine biosynthesis enzymes	86.36	99.31	AAK74739
NONAKEBI_2	24417	23713	covR	1.35e-132	responder protein	85.53	100.00	AAK71319
NONAKEBI_22	32728	32057	rr01	2.10e-125	response regulator	83.93	99.56	CAB54566
NONAKEBI_2	24417	23713	walR	5.68e-123	DNA-binding response regulator	82.13	100.00	ANC99504
NONAKEBI_27	5992	6660	CiaR	8.45e-120	two-component response regulator	84.31	99.55	AAK74935
NONAKEBI_56	66103	66789	CovR	4.06e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
NONAKEBI_27	5992	6663	ciaR	8.31e-118	two component system response regulator	82.14	99.12	AIK75708
NONAKEBI_12	37391	37786	SpxA2	7.55e-76	transcriptional regulator	90.91	100.00	ERL21461
NONAKEBI_42	83407	83006	SpxA1	1.95e-67	transcriptional regulator	80.60	100.00	ERL19273
NONAKEBI_9	25380	25093	spr0479	2.98e-49	essential gene	86.46	98.97	AAK99283
NONAKEBI_59	5641	5387	spr1327	7.36e-45	essential gene	94.12	100.00	AAL00131
NONAKEBI_48	75818	75555	spr0175	3.29e-42	pathogenitcity related	84.09	100.00	AAK98979
NONAKEBI_48	74991	74725	spr0177	7.19e-34	essential gene	84.27	88.12	AAK98981
NONAKEBI_1	6262	6762	RopE (M5005_Spy_1611)	1.75e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
NONAKEBI_11	15527	13230	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
NONAKEBI_53	24912	25931	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451