Genome ID：GCA_020076015.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	22	34	40.50

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
PCFHLFBB_6	25913	27172	STER_RS07100	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681445
PCFHLFBB_27	60399	60992	STR_RS05880	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
PCFHLFBB_13	20641	21480	cbpD	0.0	Autolysin	Exoenzyme	99.88	100.00	WP_011226733
PCFHLFBB_27	60399	60992	STER_RS06030	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
PCFHLFBB_27	60399	60992	STU_RS15260	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
PCFHLFBB_6	27169	28145	STER_RS07095	0.0	Capsule	Immune modulation	99.59	99.90	WP_011681444
PCFHLFBB_18	277	1935	fbp54	0.0	FBPs	Adherence	99.52	100.00	WP_011227179
PCFHLFBB_6	28163	29131	STER_RS07090	0.0	Capsule	Immune modulation	99.28	100.00	WP_011681443
PCFHLFBB_27	24872	25633	srtA	0.0	Sortase A	Exoenzyme	99.21	100.00	-
PCFHLFBB_27	59530	60399	rfbA	0.0	Capsule	Immune modulation	99.08	100.00	WP_011681286
PCFHLFBB_27	105023	105813	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.99	100.00	-
PCFHLFBB_3	16382	17113	STR_RS05260	0.0	Capsule	Immune modulation	98.50	100.00	WP_011227248
PCFHLFBB_3	17114	18574	STER_RS05320	0.0	Capsule	Immune modulation	98.49	100.00	WP_011681177
PCFHLFBB_6	29133	29848	STER_RS07085	0.0	Capsule	Immune modulation	98.32	99.86	WP_011681442
PCFHLFBB_6	30194	30964	STER_RS07075	0.0	Capsule	Immune modulation	98.18	99.23	WP_011681440
PCFHLFBB_3	16382	17113	STU_RS14645	0.0	Capsule	Immune modulation	97.81	100.00	WP_011226048
PCFHLFBB_3	16382	17113	STER_RS05315	0.0	Capsule	Immune modulation	97.54	100.00	WP_011681176
PCFHLFBB_3	17114	18574	STU_RS14650	0.0	Capsule	Immune modulation	97.47	100.21	WP_011226049
PCFHLFBB_6	24943	25794	rfbD	0.0	Capsule	Immune modulation	97.30	100.00	WP_014621820
PCFHLFBB_11	9863	14758	SAG_RS09105	0.0	Agglutinin receptor	Adherence	96.89	100.00	WP_000167699
PCFHLFBB_3	14931	15671	STER_RS05305	0.0	Capsule	Immune modulation	96.76	100.00	WP_011681174
PCFHLFBB_3	17114	18574	STR_RS05265	0.0	Capsule	Immune modulation	96.65	100.21	WP_041827043
PCFHLFBB_3	14931	15671	STU_RS14635	0.0	Capsule	Immune modulation	96.49	100.00	WP_011226046
PCFHLFBB_3	14936	15671	STR_RS05250	0.0	Capsule	Immune modulation	96.20	98.13	WP_011227246
PCFHLFBB_3	15681	16373	STR_RS05255	0.0	Capsule	Immune modulation	95.81	100.00	WP_011227247
PCFHLFBB_3	15681	16373	STU_RS14640	0.0	Capsule	Immune modulation	95.81	100.00	WP_011226047
PCFHLFBB_11	9863	14806	SSU98_0978	0.0	Agglutinin receptor	Adherence	95.81	99.82	YP_001200536
PCFHLFBB_11	9863	14806	SSU05_0965	0.0	Agglutinin receptor	Adherence	95.79	99.82	YP_001198331
PCFHLFBB_3	13507	14874	STU_RS14630	0.0	Capsule	Immune modulation	95.61	100.00	WP_011226045
PCFHLFBB_3	13509	14874	STER_RS05300	0.0	Capsule	Immune modulation	94.29	99.85	WP_011681173
PCFHLFBB_3	15681	16373	STER_RS05310	0.0	Capsule	Immune modulation	89.75	100.00	WP_011681175
PCFHLFBB_11	48197	49500	eno	0.0	Streptococcal enolase	Exoenzyme	88.09	99.54	WP_000022832
PCFHLFBB_17	14294	15304	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.92	99.51	WP_002986042
PCFHLFBB_2	62896	64179	tig/ropA	0.0	Trigger factor	Stress survival	80.65	99.77	WP_000107753
PCFHLFBB_27	61421	62467	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
PCFHLFBB_11	14779	9866	B9H01_RS04765	0.0	glucan-binding protein	96.40	99.70	AUS90958
PCFHLFBB_27	22185	21202	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
PCFHLFBB_14	13657	12584	MntE	0.0	manganese homeostasis	94.13	99.72	ABF32167
PCFHLFBB_11	133056	132088	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
PCFHLFBB_21	153977	156280	pfl2(Sp_0459)	0.0	formate acetyltransferase	93.10	99.22	AAK74619
PCFHLFBB_34	65714	64233	SPD_0310	0.0	UPF0371 protein SPD_0310	92.11	100.00	ABJ54480
PCFHLFBB_16	11291	9045	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
PCFHLFBB_13	1850	852	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
PCFHLFBB_15	15255	14284	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
PCFHLFBB_21	24112	22961	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
PCFHLFBB_6	11904	13892	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
PCFHLFBB_27	38381	40111	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.04	100.00	AAK34199
PCFHLFBB_44	62688	61210	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
PCFHLFBB_11	49500	48199	Eno	0.0	enolase	86.21	99.77	ABP90468
PCFHLFBB_44	47465	45573	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
PCFHLFBB_16	6120	7829	PGM	0.0	phosphoglucomutase	83.89	99.65	ACH87041
PCFHLFBB_3	49821	50831	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
PCFHLFBB_46	62346	63707	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
PCFHLFBB_8	33217	31325	PepO	0.0	endopeptidase	80.19	100.00	ABF32980
PCFHLFBB_11	63929	63039	bglB	5.14e-179	putative phospho--glucosidase	88.55	99.66	AAK33487
PCFHLFBB_4	41447	42385	SP_0676	9.91e-169	transcription facot	81.15	97.20	AAK74821
PCFHLFBB_16	8853	7996	metF	7.81e-167	methionine biosynthesis enzymes	86.36	99.31	AAK74739
PCFHLFBB_27	133454	134158	covR	5.75e-132	responder protein	85.53	100.00	AAK71319
PCFHLFBB_34	93321	93992	rr01	3.06e-126	response regulator	84.38	99.56	CAB54566
PCFHLFBB_27	133454	134158	walR	2.72e-122	DNA-binding response regulator	81.70	100.00	ANC99504
PCFHLFBB_43	84025	84711	CovR	5.08e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
PCFHLFBB_16	2166	1498	CiaR	6.47e-119	two-component response regulator	83.86	99.55	AAK74935
PCFHLFBB_16	2166	1495	ciaR	6.43e-117	two component system response regulator	81.70	99.12	AIK75708
PCFHLFBB_13	576	181	SpxA2	4.29e-76	transcriptional regulator	90.91	100.00	ERL21461
PCFHLFBB_46	51189	50788	SpxA1	1.75e-67	transcriptional regulator	80.60	100.00	ERL19273
PCFHLFBB_7	25405	25118	spr0479	3.33e-49	essential gene	86.46	98.97	AAK99283
PCFHLFBB_11	167474	167220	spr1327	2.61e-45	essential gene	95.29	100.00	AAL00131
PCFHLFBB_44	13857	14120	spr0175	4.46e-42	pathogenitcity related	84.09	100.00	AAK98979
PCFHLFBB_44	14660	14950	spr0177	2.62e-37	essential gene	81.00	98.02	AAK98981
PCFHLFBB_2	62738	62238	RopE (M5005_Spy_1611)	3.66e-76	probable DNA-directed RNA polymerase subunit delta	80.84	87.43	AAK34603
PCFHLFBB_21	153977	156274	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.07	98.08	MYN69560
PCFHLFBB_8	18760	17741	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451