Genome ID：GCA_020404185.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
1	23	34	41.06

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
OOOLKEME_24	72209	74128	tet(M)	ARO:3000186	tet(M)	99.37	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
OOOLKEME_24	72209	74128	tet(M)	Doxycycline, Tetracycline, Minocycline	99.90	100.00	X75073

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
OOOLKEME_24	72212	74128	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	EXACTX	100.00	100.00	WP_000691727.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
OOOLKEME_18	160298	161663	STER_RS05300	0.0	Capsule	Immune modulation	95.24	99.85	WP_011681173
OOOLKEME_1	227926	228777	rfbD	0.0	Capsule	Immune modulation	94.95	100.00	WP_014621820
OOOLKEME_18	160296	161663	STU_RS14630	0.0	Capsule	Immune modulation	94.30	100.00	WP_011226045
OOOLKEME_18	163903	165363	STU_RS14650	0.0	Capsule	Immune modulation	94.05	100.14	WP_011226049
OOOLKEME_18	161720	162460	STER_RS05305	0.0	Capsule	Immune modulation	93.93	100.00	WP_011681174
OOOLKEME_18	163903	165363	STER_RS05320	0.0	Capsule	Immune modulation	93.91	100.00	WP_011681177
OOOLKEME_1	229878	231149	STU_RS16265	0.0	Capsule	Immune modulation	93.63	99.76	WP_011226331
OOOLKEME_18	161720	162460	STU_RS14635	0.0	Capsule	Immune modulation	93.25	100.00	WP_011226046
OOOLKEME_18	163903	165363	STR_RS05265	0.0	Capsule	Immune modulation	93.16	100.14	WP_041827043
OOOLKEME_1	231152	232110	STU_RS16260	0.0	Capsule	Immune modulation	92.81	94.86	WP_011226330
OOOLKEME_1	238974	240758	STU_RS16230	0.0	Capsule	Immune modulation	92.77	100.00	WP_011226325
OOOLKEME_18	161725	162460	STR_RS05250	0.0	Capsule	Immune modulation	92.66	98.13	WP_011227246
OOOLKEME_18	163171	163902	STU_RS14645	0.0	Capsule	Immune modulation	92.62	100.00	WP_011226048
OOOLKEME_18	163171	163902	STER_RS05315	0.0	Capsule	Immune modulation	92.49	100.00	WP_011681176
OOOLKEME_1	234969	235925	STU_RS16250	0.0	Capsule	Immune modulation	92.48	100.00	WP_011226328
OOOLKEME_1	235909	236718	STU_RS16245	0.0	Capsule	Immune modulation	92.36	99.88	WP_002948020
OOOLKEME_1	236718	237923	STU_RS16240	0.0	Capsule	Immune modulation	91.87	100.00	WP_011226326
OOOLKEME_18	163171	163902	STR_RS05260	0.0	Capsule	Immune modulation	91.67	100.00	WP_011227248
OOOLKEME_1	237943	238977	STU_RS16235	0.0	Capsule	Immune modulation	91.48	99.15	WP_002948022
OOOLKEME_1	233824	234972	STU_RS16255	0.0	Capsule	Immune modulation	91.39	99.91	WP_041828290
OOOLKEME_26	120081	120950	rfbA	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681286
OOOLKEME_26	119488	120081	STR_RS05880	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
OOOLKEME_26	119488	120081	STER_RS06030	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
OOOLKEME_26	119488	120081	STU_RS15260	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
OOOLKEME_18	40849	42507	fbp54	0.0	FBPs	Adherence	90.48	99.94	WP_011227179
OOOLKEME_23	188575	189585	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
OOOLKEME_22	167505	168808	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
OOOLKEME_18	162470	163162	STR_RS05255	0.0	Capsule	Immune modulation	88.18	99.86	WP_011227247
OOOLKEME_18	162470	163162	STU_RS14640	0.0	Capsule	Immune modulation	88.18	99.86	WP_011226047
OOOLKEME_2	95161	96066	cbpD	0.0	Autolysin	Exoenzyme	87.86	93.50	WP_082302295
OOOLKEME_18	162470	163162	STER_RS05310	0.0	Capsule	Immune modulation	87.61	99.86	WP_011681175
OOOLKEME_23	100679	101440	srtA	0.0	Sortase A	Exoenzyme	84.53	99.87	-
OOOLKEME_26	118241	119287	rfbB	0.0	Capsule	Immune modulation	80.99	100.00	WP_009659423
OOOLKEME_9	210105	211388	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
OOOLKEME_23	104129	105103	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.31	99.09	AAK75326
OOOLKEME_23	92541	91468	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
OOOLKEME_1	57702	55396	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
OOOLKEME_25	19044	17563	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
OOOLKEME_3	59005	58037	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
OOOLKEME_23	73483	71237	metE	0.0	methionine biosynthesis enzymes	92.12	100.00	AAK74738
OOOLKEME_5	3464	4435	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
OOOLKEME_23	160529	153966	PrtA	0.0	serine protease	90.05	101.96	ABJ55268
OOOLKEME_22	1741	11	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
OOOLKEME_1	187111	188262	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
OOOLKEME_1	215463	217451	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
OOOLKEME_21	184752	183274	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
OOOLKEME_22	168808	167507	Eno	0.0	enolase	86.44	99.77	ABP90468
OOOLKEME_21	169386	167494	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
OOOLKEME_23	68318	70027	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
OOOLKEME_5	39343	40434	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
OOOLKEME_21	28666	29676	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
OOOLKEME_18	71044	69683	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
OOOLKEME_22	183224	182334	bglB	1.17e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
OOOLKEME_23	29050	30000	SP_0676	3.24e-170	transcription facot	81.39	98.45	AAK74821
OOOLKEME_23	71050	70193	metF	5.13e-169	methionine biosynthesis enzymes	87.76	99.31	AAK74739
OOOLKEME_18	211113	210409	covR	9.48e-127	responder protein	85.53	100.00	AAK71319
OOOLKEME_25	81642	82313	rr01	9.82e-127	response regulator	84.38	99.56	CAB54566
OOOLKEME_23	64350	63679	ciaR	9.35e-125	two component system response regulator	85.71	99.12	AIK75708
OOOLKEME_23	64350	63682	CiaR	1.76e-124	two-component response regulator	87.00	99.55	AAK74935
OOOLKEME_18	211113	210409	walR	2.15e-120	DNA-binding response regulator	82.13	100.00	ANC99504
OOOLKEME_9	53705	53019	CovR	4.66e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
OOOLKEME_5	40608	41003	SpxA2	4.04e-76	transcriptional regulator	91.67	100.00	ERL21461
OOOLKEME_18	82515	82916	SpxA1	5.45e-70	transcriptional regulator	82.84	100.00	ERL19273
OOOLKEME_4	6729	6316	GrpE	4.20e-68	protein grpE	81.88	80.59	ABP89267
OOOLKEME_9	30493	30206	spr0479	5.32e-48	essential gene	85.42	98.97	AAK99283
OOOLKEME_3	92759	92505	spr1327	5.24e-45	essential gene	92.94	100.00	AAL00131
OOOLKEME_21	120305	120568	spr0175	1.09e-42	pathogenitcity related	85.23	100.00	AAK98979
OOOLKEME_21	121129	121395	spr0177	2.42e-41	essential gene	83.15	88.12	AAK98981
OOOLKEME_9	209938	209447	RopE (M5005_Spy_1611)	1.03e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
OOOLKEME_1	57702	55402	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
OOOLKEME_21	65104	64085	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451