Genome ID：GCA_020538165.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
1	15	33	36.26

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
OGGFDOBN_15	23214	24692	lsaC	ARO:3003112	lsaC	99.39	100.00	HM990671.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
OGGFDOBN_15	23214	24692	lsa(C)	Lincomycin, Clindamycin, Dalfopristin, Pristinamycin IIA, Virginiamycin M, Tiamulin	99.80	100.00	HM990671

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
OGGFDOBN_15	23217	24692	lsa(C)	ABC-F type ribosomal protection protein Lsa(C)	BLASTX	99.39	100.00	WP_063851347.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
OGGFDOBN_51	52228	53079	rfbD	0.0	Capsule	Immune modulation	94.72	100.00	WP_014621820
OGGFDOBN_49	91205	92665	STU_RS14650	0.0	Capsule	Immune modulation	94.18	100.14	WP_011226049
OGGFDOBN_49	91205	92665	STER_RS05320	0.0	Capsule	Immune modulation	94.05	100.00	WP_011681177
OGGFDOBN_49	91205	92665	STR_RS05265	0.0	Capsule	Immune modulation	93.29	100.14	WP_041827043
OGGFDOBN_49	94906	96271	STER_RS05300	0.0	Capsule	Immune modulation	92.98	99.71	WP_011681173
OGGFDOBN_49	94906	96273	STU_RS14630	0.0	Capsule	Immune modulation	92.76	100.00	WP_011226045
OGGFDOBN_32	54079	54672	STR_RS05880	0.0	Capsule	Immune modulation	92.09	100.00	WP_011226149
OGGFDOBN_32	54079	54672	STER_RS06030	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
OGGFDOBN_32	54079	54672	STU_RS15260	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
OGGFDOBN_32	53210	54079	rfbA	0.0	Capsule	Immune modulation	91.84	100.00	WP_011681286
OGGFDOBN_4	22261	23919	fbp54	0.0	FBPs	Adherence	91.69	99.94	WP_011227179
OGGFDOBN_49	92666	93397	STU_RS14645	0.0	Capsule	Immune modulation	91.67	100.00	WP_011226048
OGGFDOBN_49	92666	93397	STER_RS05315	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681176
OGGFDOBN_10	19413	20252	cbpD	0.0	Autolysin	Exoenzyme	91.19	100.00	WP_011226733
OGGFDOBN_49	94108	94848	STER_RS05305	0.0	Capsule	Immune modulation	90.84	99.87	WP_011681174
OGGFDOBN_49	92666	93397	STR_RS05260	0.0	Capsule	Immune modulation	90.71	100.00	WP_011227248
OGGFDOBN_49	94108	94848	STU_RS14635	0.0	Capsule	Immune modulation	89.89	99.87	WP_011226046
OGGFDOBN_49	94108	94843	STR_RS05250	0.0	Capsule	Immune modulation	89.55	98.00	WP_011227246
OGGFDOBN_1	80116	81419	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
OGGFDOBN_52	89538	90548	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.46	99.80	WP_002986042
OGGFDOBN_49	93406	94098	STU_RS14640	0.0	Capsule	Immune modulation	85.45	99.86	WP_011226047
OGGFDOBN_49	93406	94098	STR_RS05255	0.0	Capsule	Immune modulation	85.16	99.86	WP_011227247
OGGFDOBN_49	93406	94098	STER_RS05310	0.0	Capsule	Immune modulation	84.87	99.86	WP_011681175
OGGFDOBN_5	33202	33963	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
OGGFDOBN_12	1877	3160	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
OGGFDOBN_32	54875	55921	rfbB	0.0	Capsule	Immune modulation	80.52	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
OGGFDOBN_5	36651	37625	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.31	99.09	AAK75326
OGGFDOBN_5	25066	23993	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
OGGFDOBN_7	22071	24377	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
OGGFDOBN_23	101934	103415	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
OGGFDOBN_5	5524	3278	metE	0.0	methionine biosynthesis enzymes	93.19	100.00	AAK74738
OGGFDOBN_1	171040	170072	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
OGGFDOBN_10	4321	5292	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
OGGFDOBN_32	27826	29556	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
OGGFDOBN_51	66798	64810	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
OGGFDOBN_51	95278	94127	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
OGGFDOBN_40	91873	90395	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
OGGFDOBN_1	81419	80118	Eno	0.0	enolase	86.44	99.77	ABP90468
OGGFDOBN_40	76526	74634	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
OGGFDOBN_5	356	2065	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
OGGFDOBN_10	41427	42518	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
OGGFDOBN_3	56011	55001	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
OGGFDOBN_4	37687	36326	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
OGGFDOBN_1	95825	94935	bglB	1.49e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
OGGFDOBN_5	3088	2231	metF	3.26e-169	methionine biosynthesis enzymes	87.06	99.31	AAK74739
OGGFDOBN_6	18791	17853	SP_0676	4.80e-169	transcription facot	81.47	97.20	AAK74821
OGGFDOBN_23	36336	35665	rr01	3.17e-127	response regulator	84.82	99.56	CAB54566
OGGFDOBN_49	46433	47137	covR	4.96e-127	responder protein	85.53	100.00	AAK71319
OGGFDOBN_21	4036	4707	ciaR	2.09e-126	two component system response regulator	86.16	99.12	AIK75708
OGGFDOBN_21	4036	4704	CiaR	3.87e-126	two-component response regulator	87.44	99.55	AAK74935
OGGFDOBN_49	46433	47137	walR	1.13e-120	DNA-binding response regulator	82.13	100.00	ANC99504
OGGFDOBN_12	162614	163300	CovR	4.76e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
OGGFDOBN_10	42691	43086	SpxA2	4.26e-76	transcriptional regulator	91.67	100.00	ERL21461
OGGFDOBN_4	49155	49556	SpxA1	8.71e-70	transcriptional regulator	82.09	100.00	ERL19273
OGGFDOBN_24	6420	6016	GrpE	2.77e-68	protein grpE	82.96	78.82	ABP89267
OGGFDOBN_12	185821	186108	spr0479	5.77e-48	essential gene	85.42	98.97	AAK99283
OGGFDOBN_1	207930	207676	spr1327	1.19e-44	essential gene	92.94	100.00	AAL00131
OGGFDOBN_40	32976	33239	spr0175	6.08e-43	pathogenitcity related	85.23	100.00	AAK98979
OGGFDOBN_40	33801	34067	spr0177	1.35e-41	essential gene	83.15	88.12	AAK98981
OGGFDOBN_12	3327	3818	RopE (M5005_Spy_1611)	1.05e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
OGGFDOBN_7	22071	24371	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
OGGFDOBN_3	19323	20342	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451