Genome ID：GCA_022509625.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	25	32	40.61

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
IAKEEGAK_5	19720	20589	rfbA	0.0	Capsule	Immune modulation	100.00	100.00	WP_011681286
IAKEEGAK_5	20589	21182	STER_RS06030	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
IAKEEGAK_5	20589	21182	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
IAKEEGAK_2	186064	187020	STU_RS16250	0.0	Capsule	Immune modulation	99.79	100.00	WP_011226328
IAKEEGAK_2	187004	187813	STU_RS16245	0.0	Capsule	Immune modulation	99.75	100.00	WP_002948020
IAKEEGAK_2	184919	186067	STU_RS16255	0.0	Capsule	Immune modulation	99.74	100.00	WP_041828290
IAKEEGAK_5	20589	21182	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
IAKEEGAK_2	187813	189018	STU_RS16240	0.0	Capsule	Immune modulation	99.58	100.00	WP_011226326
IAKEEGAK_2	190090	191874	STU_RS16230	0.0	Capsule	Immune modulation	99.55	100.00	WP_011226325
IAKEEGAK_2	180572	181423	rfbD	0.0	Capsule	Immune modulation	99.53	100.00	WP_014621820
IAKEEGAK_2	183800	184810	STU_RS16260	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226330
IAKEEGAK_2	189038	190093	STU_RS16235	0.0	Capsule	Immune modulation	99.43	100.00	WP_002948022
IAKEEGAK_10	98679	100337	fbp54	0.0	FBPs	Adherence	99.34	100.00	WP_011227179
IAKEEGAK_8	110819	111550	STER_RS05315	0.0	Capsule	Immune modulation	99.04	100.00	WP_011681176
IAKEEGAK_8	110819	111550	STU_RS14645	0.0	Capsule	Immune modulation	98.77	100.00	WP_011226048
IAKEEGAK_8	110819	111550	STR_RS05260	0.0	Capsule	Immune modulation	98.63	100.00	WP_011227248
IAKEEGAK_8	44026	44814	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.36	99.75	-
IAKEEGAK_9	647	2062	STER_RS05250	0.0	Capsule	Immune modulation	97.81	100.00	WP_011681165
IAKEEGAK_3	49207	49968	srtA	0.0	Sortase A	Exoenzyme	97.64	100.00	-
IAKEEGAK_20	16103	17062	cbpD	0.0	Autolysin	Exoenzyme	97.63	99.90	WP_082302295
IAKEEGAK_2	182526	183797	STU_RS16265	0.0	Capsule	Immune modulation	97.48	99.76	WP_011226331
IAKEEGAK_8	109358	110818	STER_RS05320	0.0	Capsule	Immune modulation	97.47	100.00	WP_011681177
IAKEEGAK_8	109358	110818	STU_RS14650	0.0	Capsule	Immune modulation	96.85	100.21	WP_011226049
IAKEEGAK_8	109358	110818	STR_RS05265	0.0	Capsule	Immune modulation	95.89	100.21	WP_041827043
IAKEEGAK_8	111559	112251	STR_RS05255	0.0	Capsule	Immune modulation	95.40	99.86	WP_011227247
IAKEEGAK_8	111559	112251	STU_RS14640	0.0	Capsule	Immune modulation	95.40	99.86	WP_011226047
IAKEEGAK_8	113076	114441	STER_RS05300	0.0	Capsule	Immune modulation	95.17	99.85	WP_011681173
IAKEEGAK_8	112261	113019	STER_RS05305	0.0	Capsule	Immune modulation	93.94	100.94	WP_011681174
IAKEEGAK_8	113076	114443	STU_RS14630	0.0	Capsule	Immune modulation	93.93	100.00	WP_011226045
IAKEEGAK_8	112261	113019	STU_RS14635	0.0	Capsule	Immune modulation	93.81	100.94	WP_011226046
IAKEEGAK_8	112261	113014	STR_RS05250	0.0	Capsule	Immune modulation	93.24	99.07	WP_011227246
IAKEEGAK_8	111559	112251	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
IAKEEGAK_19	116321	117624	eno	0.0	Streptococcal enolase	Exoenzyme	88.10	99.46	WP_000022832
IAKEEGAK_43	14446	15456	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.45	99.90	WP_002986042
IAKEEGAK_5	21611	22657	rfbB	0.0	Capsule	Immune modulation	80.61	100.00	WP_009659423
IAKEEGAK_32	60017	61300	tig/ropA	0.0	Trigger factor	Stress survival	80.58	99.77	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
IAKEEGAK_3	46520	45537	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
IAKEEGAK_19	13908	12835	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
IAKEEGAK_19	201022	200054	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
IAKEEGAK_2	15603	13300	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
IAKEEGAK_2	286803	285322	SPD_0310	0.0	UPF0371 protein SPD_0310	92.31	100.00	ABJ54480
IAKEEGAK_18	11368	9122	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
IAKEEGAK_36	2088	1096	recA	0.0	DNA recombination and repair	91.24	85.31	AAL00560
IAKEEGAK_39	15876	14905	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
IAKEEGAK_2	129388	130539	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
IAKEEGAK_2	165280	167268	uvrB	0.0	excinuclease ABC, B subunit	88.84	100.00	AE014259_2
IAKEEGAK_3	62716	64446	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	88.04	100.00	AAK34199
IAKEEGAK_1	27433	28911	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
IAKEEGAK_19	117624	116323	Eno	0.0	enolase	86.21	99.77	ABP90468
IAKEEGAK_1	42623	44515	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
IAKEEGAK_18	6197	7906	PGM	0.0	phosphoglucomutase	83.89	99.65	ACH87041
IAKEEGAK_23	14694	13684	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
IAKEEGAK_10	74377	75738	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
IAKEEGAK_1	123150	125042	PepO	0.0	endopeptidase	80.03	100.00	ABF32980
IAKEEGAK_19	132059	131169	bglB	7.44e-178	putative phospho--glucosidase	88.22	99.66	AAK33487
IAKEEGAK_13	10453	11391	SP_0676	2.76e-169	transcription facot	81.15	97.20	AAK74821
IAKEEGAK_18	8930	8073	metF	1.50e-166	methionine biosynthesis enzymes	86.36	99.31	AAK74739
IAKEEGAK_8	72650	73354	covR	2.90e-132	responder protein	85.53	100.00	AAK71319
IAKEEGAK_2	305779	306450	rr01	5.10e-125	response regulator	83.93	99.56	CAB54566
IAKEEGAK_8	72650	73354	walR	1.22e-122	DNA-binding response regulator	82.13	100.00	ANC99504
IAKEEGAK_18	2243	1575	CiaR	1.64e-119	two-component response regulator	84.75	99.55	AAK74935
IAKEEGAK_29	9632	8946	CovR	4.50e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
IAKEEGAK_18	2243	1572	ciaR	1.78e-117	two component system response regulator	82.59	99.12	AIK75708
IAKEEGAK_36	784	389	SpxA2	8.17e-76	transcriptional regulator	90.15	100.00	ERL21461
IAKEEGAK_22	25699	25412	spr0479	2.97e-49	essential gene	86.46	98.97	AAK99283
IAKEEGAK_19	235431	235177	spr1327	3.88e-45	essential gene	95.29	100.00	AAL00131
IAKEEGAK_1	85224	84961	spr0175	6.13e-42	pathogenitcity related	84.09	100.00	AAK98979
IAKEEGAK_1	84397	84131	spr0177	1.34e-33	essential gene	84.27	88.12	AAK98981
IAKEEGAK_32	59859	59359	RopE (M5005_Spy_1611)	1.79e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
IAKEEGAK_2	15603	13306	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
IAKEEGAK_1	137559	138578	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	95.88	100.00	ABJ55451