Genome ID：GCA_024296065.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	37	43.09

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
CIMEBHAO_23	180510	181727	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
CIMEBHAO_23	178927	180390	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	99.93	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
CIMEBHAO_23	180513	181727	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
CIMEBHAO_23	178930	180390	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
CIMEBHAO_1	46561	48021	STER_RS05320	0.0	Capsule	Immune modulation	97.06	100.00	WP_011681177
CIMEBHAO_1	46561	48021	STU_RS14650	0.0	Capsule	Immune modulation	96.72	100.21	WP_011226049
CIMEBHAO_1	46561	48021	STR_RS05265	0.0	Capsule	Immune modulation	96.17	100.21	WP_041827043
CIMEBHAO_1	50261	51626	STER_RS05300	0.0	Capsule	Immune modulation	95.09	99.85	WP_011681173
CIMEBHAO_12	163386	164237	rfbD	0.0	Capsule	Immune modulation	94.95	100.00	WP_014621820
CIMEBHAO_1	49464	50204	STER_RS05305	0.0	Capsule	Immune modulation	94.60	100.00	WP_011681174
CIMEBHAO_1	50261	51628	STU_RS14630	0.0	Capsule	Immune modulation	94.59	100.00	WP_011226045
CIMEBHAO_1	49464	50204	STU_RS14635	0.0	Capsule	Immune modulation	94.20	100.00	WP_011226046
CIMEBHAO_12	161014	162285	STU_RS16265	0.0	Capsule	Immune modulation	93.63	99.76	WP_011226331
CIMEBHAO_1	49464	50199	STR_RS05250	0.0	Capsule	Immune modulation	93.61	98.13	WP_011227246
CIMEBHAO_12	155439	156248	STU_RS16245	0.0	Capsule	Immune modulation	93.22	99.88	WP_002948020
CIMEBHAO_12	156232	157188	STU_RS16250	0.0	Capsule	Immune modulation	92.58	100.00	WP_011226328
CIMEBHAO_12	151397	153181	STU_RS16230	0.0	Capsule	Immune modulation	92.55	100.00	WP_011226325
CIMEBHAO_12	157185	158333	STU_RS16255	0.0	Capsule	Immune modulation	92.43	100.00	WP_041828290
CIMEBHAO_1	48022	48753	STU_RS14645	0.0	Capsule	Immune modulation	92.08	100.00	WP_011226048
CIMEBHAO_12	154234	155439	STU_RS16240	0.0	Capsule	Immune modulation	92.04	100.00	WP_011226326
CIMEBHAO_1	48022	48753	STER_RS05315	0.0	Capsule	Immune modulation	91.67	100.00	WP_011681176
CIMEBHAO_12	153178	154212	STU_RS16235	0.0	Capsule	Immune modulation	91.48	99.15	WP_002948022
CIMEBHAO_23	33404	34273	rfbA	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681286
CIMEBHAO_1	159669	161326	fbp54	0.0	FBPs	Adherence	91.14	99.88	WP_011227179
CIMEBHAO_1	48022	48753	STR_RS05260	0.0	Capsule	Immune modulation	91.12	100.00	WP_011227248
CIMEBHAO_23	32811	33404	STR_RS05880	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
CIMEBHAO_23	32811	33404	STER_RS06030	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
CIMEBHAO_23	32811	33404	STU_RS15260	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
CIMEBHAO_1	48762	49454	STR_RS05255	0.0	Capsule	Immune modulation	88.92	99.71	WP_011227247
CIMEBHAO_1	48762	49454	STU_RS14640	0.0	Capsule	Immune modulation	88.92	99.71	WP_011226047
CIMEBHAO_29	105136	106041	cbpD	0.0	Autolysin	Exoenzyme	88.85	93.50	WP_082302295
CIMEBHAO_23	205703	207006	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
CIMEBHAO_9	14231	15241	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.36	99.80	WP_002986042
CIMEBHAO_1	48762	49454	STER_RS05310	0.0	Capsule	Immune modulation	87.05	99.71	WP_011681175
CIMEBHAO_1	315025	315786	srtA	0.0	Sortase A	Exoenzyme	85.19	99.87	-
CIMEBHAO_23	31500	32546	rfbB	0.0	Capsule	Immune modulation	80.90	100.00	WP_009659423
CIMEBHAO_33	89430	90713	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
CIMEBHAO_1	175001	173235	spxB	0.0	pyruvate oxidase gene	97.62	99.66	AAB40976
CIMEBHAO_1	306895	305822	MntE	0.0	manganese homeostasis	95.81	99.72	ABF32167
CIMEBHAO_1	318475	319449	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	95.69	99.09	AAK75326
CIMEBHAO_31	114734	112428	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
CIMEBHAO_3	6137	7618	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
CIMEBHAO_29	12597	11629	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
CIMEBHAO_1	278838	276592	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
CIMEBHAO_5	3472	4443	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
CIMEBHAO_2	10021	3473	PrtA	0.0	serine protease	90.30	101.73	ABJ55268
CIMEBHAO_23	59656	57926	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
CIMEBHAO_12	178103	176115	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
CIMEBHAO_12	206710	205559	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
CIMEBHAO_30	178	1656	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
CIMEBHAO_23	207006	205705	Eno	0.0	enolase	86.44	99.77	ABP90468
CIMEBHAO_30	15526	17418	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.42	98.90	ABP91129
CIMEBHAO_1	273673	275382	PGM	0.0	phosphoglucomutase	84.94	99.65	ACH87041
CIMEBHAO_5	38616	39707	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
CIMEBHAO_30	151591	150581	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
CIMEBHAO_1	143810	145171	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
CIMEBHAO_23	221412	220522	bglB	1.64e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
CIMEBHAO_1	234410	235360	SP_0676	6.67e-170	transcription facot	81.39	98.45	AAK74821
CIMEBHAO_1	276405	275548	metF	1.63e-169	methionine biosynthesis enzymes	88.11	99.31	AAK74739
CIMEBHAO_15	1441	2145	endA	5.14e-142	membrane surface localized endonuclease	88.94	85.77	CAA38134
CIMEBHAO_2	35534	34863	rr01	1.40e-127	response regulator	84.82	99.56	CAB54566
CIMEBHAO_1	1777	2481	covR	1.61e-126	responder protein	85.53	100.00	AAK71319
CIMEBHAO_1	269707	269039	CiaR	3.45e-125	two-component response regulator	87.44	99.55	AAK74935
CIMEBHAO_1	269707	269036	ciaR	2.25e-124	two component system response regulator	85.71	99.12	AIK75708
CIMEBHAO_32	46563	47249	CovR	2.22e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
CIMEBHAO_1	1777	2481	walR	3.67e-120	DNA-binding response regulator	82.13	100.00	ANC99504
CIMEBHAO_5	39880	40275	SpxA2	3.97e-76	transcriptional regulator	91.67	100.00	ERL21461
CIMEBHAO_1	132313	131912	SpxA1	7.42e-70	transcriptional regulator	82.84	100.00	ERL19273
CIMEBHAO_34	6313	5900	GrpE	6.78e-68	protein grpE	81.88	80.59	ABP89267
CIMEBHAO_32	69771	70058	spr0479	2.16e-48	essential gene	85.42	98.97	AAK99283
CIMEBHAO_29	53392	53138	spr1327	8.90e-45	essential gene	92.94	100.00	AAL00131
CIMEBHAO_30	59233	58970	spr0175	7.91e-43	pathogenitcity related	85.23	100.00	AAK98979
CIMEBHAO_30	58409	58143	spr0177	1.76e-41	essential gene	83.15	88.12	AAK98981
CIMEBHAO_33	89263	88772	RopE (M5005_Spy_1611)	4.46e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
CIMEBHAO_15	2	1210	murAA (B9H01_RS05665)	0.0	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	80.89	94.38	VTT12277
CIMEBHAO_31	114734	112434	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
CIMEBHAO_30	114905	115924	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451