Genome ID：GCA_025186665.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	23	34	41.05

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HHEELPKI_78	96848	97441	STR_RS05880	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
HHEELPKI_78	96848	97441	STER_RS06030	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
HHEELPKI_78	96848	97441	STU_RS15260	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
HHEELPKI_21	129571	130527	STU_RS16250	0.0	Capsule	Immune modulation	99.79	100.00	WP_011226328
HHEELPKI_21	133597	135381	STU_RS16230	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226325
HHEELPKI_21	128426	129574	STU_RS16255	0.0	Capsule	Immune modulation	99.65	100.00	WP_041828290
HHEELPKI_21	130511	131320	STU_RS16245	0.0	Capsule	Immune modulation	99.63	100.00	WP_002948020
HHEELPKI_21	132545	133600	STU_RS16235	0.0	Capsule	Immune modulation	99.53	100.00	WP_002948022
HHEELPKI_21	131320	132525	STU_RS16240	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226326
HHEELPKI_3	10863	12521	fbp54	0.0	FBPs	Adherence	99.46	100.00	WP_011227179
HHEELPKI_78	97441	98310	rfbA	0.0	Capsule	Immune modulation	99.42	100.00	WP_011681286
HHEELPKI_21	124079	124930	rfbD	0.0	Capsule	Immune modulation	99.41	100.00	WP_014621820
HHEELPKI_21	127307	128317	STU_RS16260	0.0	Capsule	Immune modulation	99.11	100.00	WP_011226330
HHEELPKI_42	18938	19906	cbpD	0.0	Autolysin	Exoenzyme	99.07	100.00	WP_082302295
HHEELPKI_78	132208	132969	srtA	0.0	Sortase A	Exoenzyme	98.82	100.00	-
HHEELPKI_78	52024	52813	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.48	99.87	-
HHEELPKI_29	1074	1814	STER_RS05305	0.0	Capsule	Immune modulation	98.38	100.00	WP_011681174
HHEELPKI_21	126033	127307	STU_RS16265	0.0	Capsule	Immune modulation	98.20	100.00	WP_011226331
HHEELPKI_29	1074	1814	STU_RS14635	0.0	Capsule	Immune modulation	98.11	100.00	WP_011226046
HHEELPKI_29	1074	1809	STR_RS05250	0.0	Capsule	Immune modulation	97.96	98.13	WP_011227246
HHEELPKI_29	372	1064	STR_RS05255	0.0	Capsule	Immune modulation	96.97	100.00	WP_011227247
HHEELPKI_29	372	1064	STU_RS14640	0.0	Capsule	Immune modulation	96.97	100.00	WP_011226047
HHEELPKI_31	9474	14369	SAG_RS09105	0.0	Agglutinin receptor	Adherence	96.94	100.00	WP_000167699
HHEELPKI_31	9474	14417	SSU98_0978	0.0	Agglutinin receptor	Adherence	95.77	99.82	YP_001200536
HHEELPKI_31	9474	14417	SSU05_0965	0.0	Agglutinin receptor	Adherence	95.75	99.82	YP_001198331
HHEELPKI_29	372	1064	STER_RS05310	0.0	Capsule	Immune modulation	91.63	100.00	WP_011681175
HHEELPKI_31	47823	49126	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
HHEELPKI_73	224	1234	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.82	99.51	WP_002986042
HHEELPKI_76	62901	64184	tig/ropA	0.0	Trigger factor	Stress survival	80.50	99.77	WP_000107753
HHEELPKI_78	95373	96419	rfbB	0.0	Capsule	Immune modulation	80.42	100.00	WP_009659423
HHEELPKI_38	2015	2598	SPD_RS01775	3.02e-149	Capsule	Immune modulation	83.08	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HHEELPKI_31	14390	9477	B9H01_RS04765	0.0	glucan-binding protein	96.34	99.70	AUS90958
HHEELPKI_78	135656	136639	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
HHEELPKI_24	13696	12623	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
HHEELPKI_8	17426	19729	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
HHEELPKI_31	132763	131795	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
HHEELPKI_33	5739	7985	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
HHEELPKI_89	49167	47686	SPD_0310	0.0	UPF0371 protein SPD_0310	91.90	100.00	ABJ54480
HHEELPKI_82	19807	20805	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
HHEELPKI_6	15296	14325	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
HHEELPKI_21	73342	74493	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
HHEELPKI_21	109109	111097	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
HHEELPKI_78	119460	117730	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.69	100.00	AAK34199
HHEELPKI_51	72373	70895	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
HHEELPKI_31	49126	47825	Eno	0.0	enolase	86.21	99.77	ABP90468
HHEELPKI_51	57177	55285	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
HHEELPKI_33	10911	9202	PGM	0.0	phosphoglucomutase	83.89	99.65	ACH87041
HHEELPKI_7	55051	54041	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
HHEELPKI_3	36523	35171	mnmE	0.0	central tRNA-modifying GTPase	82.12	98.91	ABP90420
HHEELPKI_7	4788	6680	PepO	0.0	endopeptidase	80.03	100.00	ABF32980
HHEELPKI_31	63559	62669	bglB	1.13e-179	putative phospho--glucosidase	88.89	99.66	AAK33487
HHEELPKI_52	11753	10818	SP_0676	2.10e-169	transcription facot	81.73	96.89	AAK74821
HHEELPKI_33	8177	9034	metF	1.34e-166	methionine biosynthesis enzymes	86.01	99.31	AAK74739
HHEELPKI_78	24330	23626	covR	9.06e-132	responder protein	85.11	100.00	AAK71319
HHEELPKI_89	77220	77891	rr01	2.70e-126	response regulator	84.38	99.56	CAB54566
HHEELPKI_78	24330	23626	walR	4.54e-122	DNA-binding response regulator	81.28	100.00	ANC99504
HHEELPKI_33	14865	15533	CiaR	5.75e-122	two-component response regulator	85.65	99.55	AAK74935
HHEELPKI_33	14865	15536	ciaR	5.60e-120	two component system response regulator	83.48	99.12	AIK75708
HHEELPKI_15	7791	7105	CovR	3.06e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
HHEELPKI_82	21081	21476	SpxA2	4.32e-76	transcriptional regulator	90.91	100.00	ERL21461
HHEELPKI_3	47688	48089	SpxA1	1.62e-67	transcriptional regulator	80.60	100.00	ERL19273
HHEELPKI_13	25423	25136	spr0479	3.35e-49	essential gene	86.46	98.97	AAK99283
HHEELPKI_42	60793	61047	spr1327	1.05e-45	essential gene	95.29	100.00	AAL00131
HHEELPKI_51	14605	14868	spr0175	4.77e-42	pathogenitcity related	84.09	100.00	AAK98979
HHEELPKI_51	15408	15698	spr0177	2.80e-37	essential gene	81.00	98.02	AAK98981
HHEELPKI_76	62743	62243	RopE (M5005_Spy_1611)	1.76e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
HHEELPKI_8	17426	19723	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
HHEELPKI_7	19189	20208	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451