Genome ID：GCA_025186965.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	26	33	42.01

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NCNHKHDH_4	52128	52918	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	100.00	100.00	-
NCNHKHDH_56	19729	20580	rfbD	0.0	Capsule	Immune modulation	100.00	100.00	WP_014621820
NCNHKHDH_4	96947	97540	STU_RS15260	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226149
NCNHKHDH_56	14132	15088	STU_RS16250	0.0	Capsule	Immune modulation	100.00	100.00	WP_011226328
NCNHKHDH_56	9278	11062	STU_RS16230	0.0	Capsule	Immune modulation	99.89	100.00	WP_011226325
NCNHKHDH_56	13339	14148	STU_RS16245	0.0	Capsule	Immune modulation	99.88	100.00	WP_002948020
NCNHKHDH_4	132306	133067	srtA	0.0	Sortase A	Exoenzyme	99.87	100.00	-
NCNHKHDH_4	96947	97540	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
NCNHKHDH_56	16342	17352	STU_RS16260	0.0	Capsule	Immune modulation	99.80	100.00	WP_011226330
NCNHKHDH_56	15085	16233	STU_RS16255	0.0	Capsule	Immune modulation	99.74	100.00	WP_041828290
NCNHKHDH_56	11059	12114	STU_RS16235	0.0	Capsule	Immune modulation	99.72	100.00	WP_002948022
NCNHKHDH_60	12997	14655	fbp54	0.0	FBPs	Adherence	99.70	100.00	WP_011227179
NCNHKHDH_4	96947	97540	STER_RS06030	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
NCNHKHDH_4	97540	98409	rfbA	0.0	Capsule	Immune modulation	99.54	100.00	WP_011681286
NCNHKHDH_61	13469	14200	STER_RS05315	0.0	Capsule	Immune modulation	99.45	100.00	WP_011681176
NCNHKHDH_61	14209	14901	STU_RS14640	0.0	Capsule	Immune modulation	99.42	100.00	WP_011226047
NCNHKHDH_56	12134	13339	STU_RS16240	0.0	Capsule	Immune modulation	99.42	100.00	WP_011226326
NCNHKHDH_61	14209	14901	STR_RS05255	0.0	Capsule	Immune modulation	98.85	100.00	WP_011227247
NCNHKHDH_10	18950	19918	cbpD	0.0	Autolysin	Exoenzyme	98.76	100.00	WP_082302295
NCNHKHDH_25	425	1840	STER_RS05250	0.0	Capsule	Immune modulation	98.73	100.00	WP_011681165
NCNHKHDH_61	12014	13468	STU_RS14650	0.0	Capsule	Immune modulation	98.62	100.00	WP_011226049
NCNHKHDH_61	12014	13468	STR_RS05265	0.0	Capsule	Immune modulation	98.49	100.00	WP_041827043
NCNHKHDH_61	14911	15651	STER_RS05305	0.0	Capsule	Immune modulation	98.38	100.00	WP_011681174
NCNHKHDH_61	13469	14200	STR_RS05260	0.0	Capsule	Immune modulation	98.22	100.00	WP_011227248
NCNHKHDH_61	13469	14200	STU_RS14645	0.0	Capsule	Immune modulation	98.09	100.00	WP_011226048
NCNHKHDH_61	14911	15646	STR_RS05250	0.0	Capsule	Immune modulation	97.96	98.13	WP_011227246
NCNHKHDH_61	14911	15651	STU_RS14635	0.0	Capsule	Immune modulation	97.71	100.00	WP_011226046
NCNHKHDH_61	12014	13468	STER_RS05320	0.0	Capsule	Immune modulation	97.60	99.79	WP_011681177
NCNHKHDH_56	17352	18626	STU_RS16265	0.0	Capsule	Immune modulation	97.57	100.00	WP_011226331
NCNHKHDH_61	15708	17075	STU_RS14630	0.0	Capsule	Immune modulation	95.69	100.00	WP_011226045
NCNHKHDH_61	15708	17071	STER_RS05300	0.0	Capsule	Immune modulation	94.94	99.71	WP_011681173
NCNHKHDH_61	17304	18295	STU_RS14625*	0.0	Capsule	Immune modulation	92.69	99.60	-
NCNHKHDH_61	14209	14901	STER_RS05310	0.0	Capsule	Immune modulation	89.32	100.00	WP_011681175
NCNHKHDH_54	19517	20820	eno	0.0	Streptococcal enolase	Exoenzyme	88.09	99.54	WP_000022832
NCNHKHDH_38	3699	4709	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.92	99.51	WP_002986042
NCNHKHDH_4	95471	96517	rfbB	0.0	Capsule	Immune modulation	80.71	100.00	WP_009659423
NCNHKHDH_3	2310	3593	tig/ropA	0.0	Trigger factor	Stress survival	80.58	99.77	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NCNHKHDH_4	135754	136737	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
NCNHKHDH_53	14019	12946	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
NCNHKHDH_67	24814	25782	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
NCNHKHDH_56	183776	186079	pfl2(Sp_0459)	0.0	formate acetyltransferase	92.97	99.22	AAK74619
NCNHKHDH_22	38080	36599	SPD_0310	0.0	UPF0371 protein SPD_0310	92.11	100.00	ABJ54480
NCNHKHDH_65	11332	9086	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
NCNHKHDH_18	1976	984	recA	0.0	DNA recombination and repair	91.24	85.31	AAL00560
NCNHKHDH_11	15473	14502	prsA2	0.0	ribose-phosphate pyrophosphokinase	90.12	100.00	ABF36968
NCNHKHDH_56	70040	68889	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.06	99.74	AAL00050
NCNHKHDH_56	35562	33580	uvrB	0.0	excinuclease ABC, B subunit	88.96	99.70	AE014259_2
NCNHKHDH_4	119560	117830	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.87	100.00	AAK34199
NCNHKHDH_62	236	1714	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.42	100.00	ADE32434
NCNHKHDH_54	19517	20818	Eno	0.0	enolase	86.21	99.77	ABP90468
NCNHKHDH_62	14972	16864	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.89	98.90	ABP91129
NCNHKHDH_65	6161	7870	PGM	0.0	phosphoglucomutase	83.89	99.65	ACH87041
NCNHKHDH_14	18851	19861	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
NCNHKHDH_66	7435	6074	mnmE	0.0	central tRNA-modifying GTPase	82.02	99.56	ABP90420
NCNHKHDH_5	4705	6597	PepO	0.0	endopeptidase	80.03	100.00	ABF32980
NCNHKHDH_54	5087	5977	bglB	7.39e-180	putative phospho--glucosidase	88.89	99.66	AAK33487
NCNHKHDH_77	45976	46914	SP_0676	3.90e-169	transcription facot	81.47	97.20	AAK74821
NCNHKHDH_65	8894	8037	metF	1.17e-166	methionine biosynthesis enzymes	86.36	99.31	AAK74739
NCNHKHDH_4	24454	23750	covR	5.79e-132	responder protein	85.53	100.00	AAK71319
NCNHKHDH_57	5309	5980	rr01	2.24e-127	response regulator	84.38	99.56	CAB54566
NCNHKHDH_4	24454	23750	walR	2.74e-122	DNA-binding response regulator	81.70	100.00	ANC99504
NCNHKHDH_19	16149	16835	CovR	1.40e-119	serves to repress GAS virulence factor-encoding genes	80.79	100.00	ACE75886
NCNHKHDH_65	2207	1539	CiaR	9.68e-119	two-component response regulator	83.86	99.55	AAK74935
NCNHKHDH_65	2207	1536	ciaR	9.62e-117	two component system response regulator	81.70	99.12	AIK75708
NCNHKHDH_18	687	292	SpxA2	2.79e-76	transcriptional regulator	90.91	100.00	ERL21461
NCNHKHDH_66	18793	19194	SpxA1	8.10e-68	transcriptional regulator	80.60	100.00	ERL19273
NCNHKHDH_8	13395	13682	spr0479	3.36e-49	essential gene	86.46	98.97	AAK99283
NCNHKHDH_10	60883	61137	spr1327	1.05e-45	essential gene	95.29	100.00	AAL00131
NCNHKHDH_63	14624	14887	spr0175	1.59e-42	pathogenitcity related	84.09	100.00	AAK98979
NCNHKHDH_63	15451	15717	spr0177	4.10e-34	essential gene	84.27	88.12	AAK98981
NCNHKHDH_3	3751	4251	RopE (M5005_Spy_1611)	3.54e-76	probable DNA-directed RNA polymerase subunit delta	80.84	87.43	AAK34603
NCNHKHDH_56	183776	186073	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.94	98.08	MYN69560
NCNHKHDH_5	19166	20185	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.18	100.00	ABJ55451