Genome ID：GCA_025187565.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
0	26	33	42.01

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
No hit found

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
No hit found

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
APPENMAO_77	31917	32510	STR_RS05880	0.0	Capsule	Immune modulation	99.83	100.00	WP_011226149
APPENMAO_7	74181	75137	STU_RS16250	0.0	Capsule	Immune modulation	99.79	100.00	WP_011226328
APPENMAO_7	75121	75930	STU_RS16245	0.0	Capsule	Immune modulation	99.75	100.00	WP_002948020
APPENMAO_77	31917	32510	STER_RS06030	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
APPENMAO_77	31917	32510	STU_RS15260	0.0	Capsule	Immune modulation	99.66	100.00	WP_011226149
APPENMAO_7	73036	74184	STU_RS16255	0.0	Capsule	Immune modulation	99.65	100.00	WP_041828290
APPENMAO_7	68689	69540	rfbD	0.0	Capsule	Immune modulation	99.53	100.00	WP_014621820
APPENMAO_7	77155	78210	STU_RS16235	0.0	Capsule	Immune modulation	99.53	100.00	WP_002948022
APPENMAO_7	75930	77135	STU_RS16240	0.0	Capsule	Immune modulation	99.50	100.00	WP_011226326
APPENMAO_34	321	1979	fbp54	0.0	FBPs	Adherence	99.46	100.00	WP_011227179
APPENMAO_7	78207	79991	STU_RS16230	0.0	Capsule	Immune modulation	99.44	100.00	WP_011226325
APPENMAO_9	13960	14559	STR_RS05245	0.0	Capsule	Immune modulation	99.17	100.00	WP_196767671
APPENMAO_77	31048	31917	rfbA	0.0	Capsule	Immune modulation	99.08	100.00	WP_011681286
APPENMAO_55	571	1986	STER_RS05250	0.0	Capsule	Immune modulation	99.01	100.00	WP_011681165
APPENMAO_77	76246	77036	cshA	0.0	Cell surface hydrophobicity proteins	Adherence	98.99	100.00	-
APPENMAO_7	71917	72927	STU_RS16260	0.0	Capsule	Immune modulation	98.91	100.00	WP_011226330
APPENMAO_1	25631	26392	srtA	0.0	Sortase A	Exoenzyme	98.82	100.00	-
APPENMAO_21	18850	19818	cbpD	0.0	Autolysin	Exoenzyme	98.76	100.00	WP_082302295
APPENMAO_9	16895	18349	STU_RS14650	0.0	Capsule	Immune modulation	98.76	100.00	WP_011226049
APPENMAO_9	16895	18349	STR_RS05265	0.0	Capsule	Immune modulation	98.62	100.00	WP_041827043
APPENMAO_9	12836	13795	STR_RS05240	0.0	Capsule	Immune modulation	98.23	100.00	WP_041827042
APPENMAO_7	70643	71917	STU_RS16265	0.0	Capsule	Immune modulation	98.20	100.00	WP_011226331
APPENMAO_9	14711	15446	STER_RS05305	0.0	Capsule	Immune modulation	97.96	99.33	WP_011681174
APPENMAO_9	14711	15446	STU_RS14635	0.0	Capsule	Immune modulation	97.83	99.33	WP_011226046
APPENMAO_9	16163	16894	STER_RS05315	0.0	Capsule	Immune modulation	97.68	100.00	WP_011681176
APPENMAO_9	14697	15446	STR_RS05250	0.0	Capsule	Immune modulation	97.47	100.00	WP_011227246
APPENMAO_9	16163	16894	STU_RS14645	0.0	Capsule	Immune modulation	97.27	100.00	WP_011226048
APPENMAO_9	16895	18349	STER_RS05320	0.0	Capsule	Immune modulation	97.06	99.79	WP_011681177
APPENMAO_9	16163	16894	STR_RS05260	0.0	Capsule	Immune modulation	96.86	100.00	WP_011227248
APPENMAO_9	15456	16137	STU_RS14640	0.0	Capsule	Immune modulation	93.25	98.41	WP_011226047
APPENMAO_9	15456	16137	STR_RS05255	0.0	Capsule	Immune modulation	92.96	98.41	WP_011227247
APPENMAO_10	106769	108072	eno	0.0	Streptococcal enolase	Exoenzyme	87.86	99.54	WP_000022832
APPENMAO_27	270	1280	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	86.92	99.51	WP_002986042
APPENMAO_9	15456	16137	STER_RS05310	0.0	Capsule	Immune modulation	85.92	98.41	WP_011681175
APPENMAO_18	62914	64197	tig/ropA	0.0	Trigger factor	Stress survival	80.58	99.77	WP_000107753
APPENMAO_77	32939	33985	rfbB	0.0	Capsule	Immune modulation	80.33	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
APPENMAO_1	22944	21961	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	94.82	100.00	AAK75326
APPENMAO_10	208729	209802	MntE	0.0	manganese homeostasis	94.41	99.72	ABF32167
APPENMAO_40	40709	43012	pfl2(Sp_0459)	0.0	formate acetyltransferase	93.10	99.22	AAK74619
APPENMAO_10	24559	25527	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
APPENMAO_64	48422	49903	SPD_0310	0.0	UPF0371 protein SPD_0310	92.11	100.00	ABJ54480
APPENMAO_11	11334	9088	metE	0.0	methionine biosynthesis enzymes	91.99	100.00	AAK74738
APPENMAO_75	10432	11430	recA	0.0	DNA recombination and repair	91.29	85.82	AAL00560
APPENMAO_33	136	1107	prsA2	0.0	ribose-phosphate pyrophosphokinase	89.81	100.00	ABF36968
APPENMAO_7	25713	26864	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
APPENMAO_7	53719	55707	uvrB	0.0	excinuclease ABC, B subunit	88.99	100.00	AE014259_2
APPENMAO_77	9900	11630	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	87.69	100.00	AAK34199
APPENMAO_4	27061	28539	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
APPENMAO_10	106769	108070	Eno	0.0	enolase	86.21	99.77	ABP90468
APPENMAO_4	42256	44148	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	86.05	98.90	ABP91129
APPENMAO_11	6162	7871	PGM	0.0	phosphoglucomutase	83.89	99.65	ACH87041
APPENMAO_13	7269	8279	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
APPENMAO_32	43857	45218	mnmE	0.0	central tRNA-modifying GTPase	82.02	99.56	ABP90420
APPENMAO_13	57536	55644	PepO	0.0	endopeptidase	80.03	100.00	ABF32980
APPENMAO_10	92337	93227	bglB	3.49e-179	putative phospho--glucosidase	88.55	99.66	AAK33487
APPENMAO_42	13343	12405	SP_0676	2.41e-169	transcription facot	81.47	97.20	AAK74821
APPENMAO_11	8896	8039	metF	2.02e-166	methionine biosynthesis enzymes	86.01	99.31	AAK74739
APPENMAO_77	104668	105372	covR	4.72e-132	responder protein	85.53	100.00	AAK71319
APPENMAO_64	29452	28781	rr01	1.72e-126	response regulator	84.38	99.56	CAB54566
APPENMAO_77	104668	105372	walR	2.23e-122	DNA-binding response regulator	81.70	100.00	ANC99504
APPENMAO_11	2208	1540	CiaR	5.35e-122	two-component response regulator	85.65	99.55	AAK74935
APPENMAO_11	2208	1537	ciaR	7.61e-120	two component system response regulator	83.48	99.12	AIK75708
APPENMAO_36	10233	9547	CovR	1.27e-118	serves to repress GAS virulence factor-encoding genes	80.35	100.00	ACE75886
APPENMAO_75	11706	12080	SpxA2	7.56e-72	transcriptional regulator	91.20	94.70	ERL21461
APPENMAO_32	32500	32099	SpxA1	1.03e-67	transcriptional regulator	80.60	100.00	ERL19273
APPENMAO_38	14808	15095	spr0479	3.07e-49	essential gene	86.46	98.97	AAK99283
APPENMAO_21	60705	60959	spr1327	1.05e-45	essential gene	95.29	100.00	AAL00131
APPENMAO_4	75794	75531	spr0175	4.31e-42	pathogenitcity related	84.09	100.00	AAK98979
APPENMAO_4	74991	74701	spr0177	2.53e-37	essential gene	81.00	98.02	AAK98981
APPENMAO_18	62756	62256	RopE (M5005_Spy_1611)	1.76e-76	probable DNA-directed RNA polymerase subunit delta	81.44	87.43	AAK34603
APPENMAO_40	40709	43006	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.07	98.08	MYN69560
APPENMAO_13	43136	42117	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	96.47	100.00	ABJ55451