Genome ID：GCA_026781755.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	21	34	40.01

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
IEGKFECF_2	5739	6956	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
IEGKFECF_2	4156	5619	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
IEGKFECF_2	5742	6956	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
IEGKFECF_2	4159	5619	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
IEGKFECF_29	93784	94593	STU_RS16245	0.0	Capsule	Immune modulation	95.80	100.00	WP_002948020
IEGKFECF_29	96781	97632	rfbD	0.0	Capsule	Immune modulation	94.48	100.00	WP_014621820
IEGKFECF_2	80581	82041	STU_RS14650	0.0	Capsule	Immune modulation	93.98	100.14	WP_011226049
IEGKFECF_2	80581	82041	STER_RS05320	0.0	Capsule	Immune modulation	93.98	100.00	WP_011681177
IEGKFECF_2	80581	82041	STR_RS05265	0.0	Capsule	Immune modulation	93.22	100.14	WP_041827043
IEGKFECF_2	76973	78340	STU_RS14630	0.0	Capsule	Immune modulation	93.13	100.00	WP_011226045
IEGKFECF_2	76975	78340	STER_RS05300	0.0	Capsule	Immune modulation	92.97	99.85	WP_011681173
IEGKFECF_29	92579	93784	STU_RS16240	0.0	Capsule	Immune modulation	92.45	100.00	WP_011226326
IEGKFECF_29	95530	96678	STU_RS16255	0.0	Capsule	Immune modulation	92.43	100.00	WP_041828290
IEGKFECF_22	264849	265442	STR_RS05880	0.0	Capsule	Immune modulation	92.42	100.00	WP_011226149
IEGKFECF_29	89760	91516	STU_RS16230	0.0	Capsule	Immune modulation	92.38	98.38	WP_011226325
IEGKFECF_22	264849	265442	STER_RS06030	0.0	Capsule	Immune modulation	92.26	100.00	WP_011226149
IEGKFECF_22	264849	265442	STU_RS15260	0.0	Capsule	Immune modulation	92.26	100.00	WP_011226149
IEGKFECF_2	79849	80580	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
IEGKFECF_29	94577	95533	STU_RS16250	0.0	Capsule	Immune modulation	91.64	100.00	WP_011226328
IEGKFECF_22	263980	264849	rfbA	0.0	Capsule	Immune modulation	91.61	100.00	WP_011681286
IEGKFECF_2	79849	80580	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
IEGKFECF_29	91513	92559	STU_RS16235	0.0	Capsule	Immune modulation	91.29	99.43	WP_002948022
IEGKFECF_13	20568	21407	cbpD	0.0	Autolysin	Exoenzyme	91.07	100.00	WP_011226733
IEGKFECF_2	79849	80580	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
IEGKFECF_2	78398	79138	STER_RS05305	0.0	Capsule	Immune modulation	90.84	99.87	WP_011681174
IEGKFECF_27	43479	45133	fbp54	0.0	FBPs	Adherence	90.52	99.70	WP_011227179
IEGKFECF_2	78398	79138	STU_RS14635	0.0	Capsule	Immune modulation	89.89	99.87	WP_011226046
IEGKFECF_2	78403	79138	STR_RS05250	0.0	Capsule	Immune modulation	89.55	98.00	WP_011227246
IEGKFECF_22	101791	103094	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
IEGKFECF_15	5795	6805	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.36	99.80	WP_002986042
IEGKFECF_2	79148	79840	STU_RS14640	0.0	Capsule	Immune modulation	85.45	99.86	WP_011226047
IEGKFECF_2	79148	79840	STR_RS05255	0.0	Capsule	Immune modulation	85.16	99.86	WP_011227247
IEGKFECF_2	79148	79840	STER_RS05310	0.0	Capsule	Immune modulation	84.87	99.86	WP_011681175
IEGKFECF_22	265645	266691	rfbB	0.0	Capsule	Immune modulation	84.54	99.90	WP_002263087
IEGKFECF_28	98284	99045	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
IEGKFECF_3	1853	3136	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
IEGKFECF_28	101734	102717	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.65	100.00	AAK75326
IEGKFECF_28	90146	89073	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
IEGKFECF_11	117855	120161	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.54	99.22	AAK74619
IEGKFECF_28	71089	68843	metE	0.0	methionine biosynthesis enzymes	93.19	100.00	AAK74738
IEGKFECF_22	11325	12293	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
IEGKFECF_6	61552	63033	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
IEGKFECF_13	35788	34817	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
IEGKFECF_4	39536	46084	PrtA	0.0	serine protease	90.35	101.73	ABJ55268
IEGKFECF_22	238598	240328	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	90.12	100.00	AAK34199
IEGKFECF_29	110096	108108	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
IEGKFECF_29	138501	137350	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
IEGKFECF_5	27797	26319	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
IEGKFECF_22	101791	103092	Eno	0.0	enolase	86.44	99.77	ABP90468
IEGKFECF_5	12449	10557	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.42	98.90	ABP91129
IEGKFECF_28	65921	67630	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
IEGKFECF_13	1903	812	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
IEGKFECF_7	104599	103589	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
IEGKFECF_27	27630	28991	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
IEGKFECF_22	87383	88273	bglB	4.83e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
IEGKFECF_28	68653	67796	metF	2.47e-170	methionine biosynthesis enzymes	88.11	99.31	AAK74739
IEGKFECF_28	26035	26997	SP_0676	3.75e-170	transcription facot	80.69	99.69	AAK74821
IEGKFECF_4	2354	3025	rr01	1.11e-127	response regulator	84.82	99.56	CAB54566
IEGKFECF_2	126979	126275	covR	4.27e-125	responder protein	85.53	100.00	AAK71319
IEGKFECF_28	61254	60583	ciaR	1.72e-124	two component system response regulator	85.71	99.12	AIK75708
IEGKFECF_28	61254	60586	CiaR	4.87e-124	two-component response regulator	86.55	99.55	AAK74935
IEGKFECF_3	150123	150809	CovR	4.49e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
IEGKFECF_2	126979	126275	walR	1.10e-118	DNA-binding response regulator	82.13	100.00	ANC99504
IEGKFECF_13	638	243	SpxA2	3.90e-76	transcriptional regulator	91.67	100.00	ERL21461
IEGKFECF_27	16156	15755	SpxA1	1.79e-70	transcriptional regulator	82.84	100.00	ERL19273
IEGKFECF_10	43547	43960	GrpE	3.84e-68	protein grpE	81.88	80.59	ABP89267
IEGKFECF_3	173341	173628	spr0479	4.35e-48	essential gene	85.42	98.97	AAK99283
IEGKFECF_9	32626	32372	spr1327	2.54e-45	essential gene	92.94	100.00	AAL00131
IEGKFECF_31	6792	6529	spr0175	8.47e-44	pathogenitcity related	85.23	100.00	AAK98979
IEGKFECF_31	5968	5702	spr0177	1.88e-42	essential gene	83.15	88.12	AAK98981
IEGKFECF_3	3303	3794	RopE (M5005_Spy_1611)	9.93e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
IEGKFECF_11	117855	120155	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
IEGKFECF_7	67909	68928	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451