Genome ID：GCA_028325525.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
3	20	33	38.70

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
FPGGHJAJ_13	138536	140014	lsaC	ARO:3003112	lsaC	99.59	100.00	HM990671.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
FPGGHJAJ_15	64253	65470	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
FPGGHJAJ_15	65590	67053	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302
FPGGHJAJ_13	138536	140014	lsa(C)	Lincomycin, Clindamycin, Dalfopristin, Pristinamycin IIA, Virginiamycin M, Tiamulin	99.86	100.00	HM990671

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
FPGGHJAJ_15	64253	65467	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
FPGGHJAJ_15	65590	67050	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1
FPGGHJAJ_13	138536	140011	lsa(C)	ABC-F type ribosomal protection protein Lsa(C)	BLASTX	99.59	100.00	WP_063851347.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
FPGGHJAJ_12	317759	318474	STER_RS07085	0.0	Capsule	Immune modulation	96.65	99.86	WP_011681442
FPGGHJAJ_8	196285	197025	STER_RS05305	0.0	Capsule	Immune modulation	95.01	100.00	WP_011681174
FPGGHJAJ_12	313598	314449	rfbD	0.0	Capsule	Immune modulation	94.72	100.00	WP_014621820
FPGGHJAJ_12	316789	317757	STER_RS07090	0.0	Capsule	Immune modulation	94.63	100.00	WP_011681443
FPGGHJAJ_8	196285	197025	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
FPGGHJAJ_8	193382	194842	STU_RS14650	0.0	Capsule	Immune modulation	93.98	100.14	WP_011226049
FPGGHJAJ_8	197082	198449	STU_RS14630	0.0	Capsule	Immune modulation	93.93	100.00	WP_011226045
FPGGHJAJ_8	193382	194842	STER_RS05320	0.0	Capsule	Immune modulation	93.84	100.00	WP_011681177
FPGGHJAJ_8	196285	197020	STR_RS05250	0.0	Capsule	Immune modulation	93.75	98.13	WP_011227246
FPGGHJAJ_8	197082	198447	STER_RS05300	0.0	Capsule	Immune modulation	93.63	99.85	WP_011681173
FPGGHJAJ_8	193382	194842	STR_RS05265	0.0	Capsule	Immune modulation	93.09	100.14	WP_041827043
FPGGHJAJ_12	318820	319596	STER_RS07075	0.0	Capsule	Immune modulation	92.66	100.00	WP_011681440
FPGGHJAJ_12	314568	315821	STER_RS07100	0.0	Capsule	Immune modulation	92.51	99.52	WP_011681445
FPGGHJAJ_8	194843	195574	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
FPGGHJAJ_8	24591	25184	STR_RS05880	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
FPGGHJAJ_8	24591	25184	STER_RS06030	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
FPGGHJAJ_8	24591	25184	STU_RS15260	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
FPGGHJAJ_8	194843	195574	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
FPGGHJAJ_8	23722	24591	rfbA	0.0	Capsule	Immune modulation	91.38	100.00	WP_011681286
FPGGHJAJ_8	303135	304792	fbp54	0.0	FBPs	Adherence	91.14	99.88	WP_011227179
FPGGHJAJ_8	194843	195574	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
FPGGHJAJ_12	15178	16188	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
FPGGHJAJ_15	36145	37448	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
FPGGHJAJ_8	195583	196275	STR_RS05255	0.0	Capsule	Immune modulation	88.04	99.86	WP_011227247
FPGGHJAJ_8	195583	196275	STU_RS14640	0.0	Capsule	Immune modulation	88.04	99.86	WP_011226047
FPGGHJAJ_8	195583	196275	STER_RS05310	0.0	Capsule	Immune modulation	87.46	99.86	WP_011681175
FPGGHJAJ_16	89168	90064	cbpD	0.0	Autolysin	Exoenzyme	84.99	93.19	WP_082302295
FPGGHJAJ_8	450156	450917	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
FPGGHJAJ_8	25387	26433	rfbB	0.0	Capsule	Immune modulation	83.97	99.90	WP_002263087
FPGGHJAJ_14	1916	3199	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
FPGGHJAJ_8	207522	208107	SPD_RS01775	1.51e-146	Capsule	Immune modulation	82.96	96.53	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
FPGGHJAJ_8	453605	454588	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.34	100.00	AAK75326
FPGGHJAJ_8	442022	440949	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
FPGGHJAJ_12	140138	137832	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
FPGGHJAJ_8	579346	580827	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
FPGGHJAJ_8	422962	420716	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
FPGGHJAJ_18	20676	21644	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
FPGGHJAJ_1	35972	35001	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
FPGGHJAJ_15	193777	195507	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
FPGGHJAJ_12	271332	272483	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
FPGGHJAJ_12	299693	301681	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
FPGGHJAJ_13	25874	27352	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
FPGGHJAJ_15	36145	37446	Eno	0.0	enolase	86.44	99.77	ABP90468
FPGGHJAJ_13	41247	43139	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
FPGGHJAJ_1	2035	944	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
FPGGHJAJ_8	417794	419503	PGM	0.0	phosphoglucomutase	84.59	99.65	ACH87041
FPGGHJAJ_13	217361	216351	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
FPGGHJAJ_8	288671	290032	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
FPGGHJAJ_15	21729	22619	bglB	1.12e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
FPGGHJAJ_8	375286	376236	SP_0676	8.82e-170	transcription facot	81.39	98.45	AAK74821
FPGGHJAJ_8	420526	419669	metF	8.36e-169	methionine biosynthesis enzymes	87.41	99.31	AAK74739
FPGGHJAJ_8	147716	148420	covR	3.17e-126	responder protein	85.53	100.00	AAK71319
FPGGHJAJ_8	516745	516074	rr01	4.97e-126	response regulator	84.38	99.56	CAB54566
FPGGHJAJ_8	413827	413156	ciaR	8.20e-125	two component system response regulator	86.16	99.12	AIK75708
FPGGHJAJ_8	413827	413159	CiaR	6.16e-124	two-component response regulator	87.00	99.55	AAK74935
FPGGHJAJ_14	152442	153128	CovR	4.50e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
FPGGHJAJ_8	147716	148420	walR	7.21e-120	DNA-binding response regulator	82.13	100.00	ANC99504
FPGGHJAJ_1	770	375	SpxA2	3.95e-76	transcriptional regulator	91.67	100.00	ERL21461
FPGGHJAJ_8	277200	276799	SpxA1	1.82e-69	transcriptional regulator	82.84	100.00	ERL19273
FPGGHJAJ_19	6515	6111	GrpE	8.14e-68	protein grpE	82.96	78.82	ABP89267
FPGGHJAJ_14	175653	175940	spr0479	5.45e-48	essential gene	85.42	98.97	AAK99283
FPGGHJAJ_17	36469	36215	spr1327	4.07e-45	essential gene	92.94	100.00	AAL00131
FPGGHJAJ_13	90328	90065	spr0175	1.27e-42	pathogenitcity related	85.23	100.00	AAK98979
FPGGHJAJ_13	89504	89238	spr0177	2.83e-41	essential gene	83.15	88.12	AAK98981
FPGGHJAJ_14	3366	3857	RopE (M5005_Spy_1611)	9.96e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
FPGGHJAJ_12	140138	137838	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
FPGGHJAJ_13	180923	181942	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451