Genome ID：GCA_028325655.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
3	20	33	38.70

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
NHBCGNOB_9	138537	140015	lsaC	ARO:3003112	lsaC	99.59	100.00	HM990671.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
NHBCGNOB_11	130128	131345	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
NHBCGNOB_11	128545	130008	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302
NHBCGNOB_9	138537	140015	lsa(C)	Lincomycin, Clindamycin, Dalfopristin, Pristinamycin IIA, Virginiamycin M, Tiamulin	99.86	100.00	HM990671

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
NHBCGNOB_11	130131	131345	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
NHBCGNOB_11	128548	130008	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1
NHBCGNOB_9	138537	140012	lsa(C)	ABC-F type ribosomal protection protein Lsa(C)	BLASTX	99.59	100.00	WP_063851347.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NHBCGNOB_7	317936	318651	STER_RS07085	0.0	Capsule	Immune modulation	96.65	99.86	WP_011681442
NHBCGNOB_6	199464	200204	STER_RS05305	0.0	Capsule	Immune modulation	95.01	100.00	WP_011681174
NHBCGNOB_7	313775	314626	rfbD	0.0	Capsule	Immune modulation	94.72	100.00	WP_014621820
NHBCGNOB_7	316966	317934	STER_RS07090	0.0	Capsule	Immune modulation	94.63	100.00	WP_011681443
NHBCGNOB_6	199464	200204	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
NHBCGNOB_6	196561	198021	STU_RS14650	0.0	Capsule	Immune modulation	93.98	100.14	WP_011226049
NHBCGNOB_6	200261	201628	STU_RS14630	0.0	Capsule	Immune modulation	93.93	100.00	WP_011226045
NHBCGNOB_6	196561	198021	STER_RS05320	0.0	Capsule	Immune modulation	93.84	100.00	WP_011681177
NHBCGNOB_6	199464	200199	STR_RS05250	0.0	Capsule	Immune modulation	93.75	98.13	WP_011227246
NHBCGNOB_6	200261	201626	STER_RS05300	0.0	Capsule	Immune modulation	93.63	99.85	WP_011681173
NHBCGNOB_6	196561	198021	STR_RS05265	0.0	Capsule	Immune modulation	93.09	100.14	WP_041827043
NHBCGNOB_7	318997	319773	STER_RS07075	0.0	Capsule	Immune modulation	92.66	100.00	WP_011681440
NHBCGNOB_7	314745	315998	STER_RS07100	0.0	Capsule	Immune modulation	92.51	99.52	WP_011681445
NHBCGNOB_6	198022	198753	STU_RS14645	0.0	Capsule	Immune modulation	91.94	100.00	WP_011226048
NHBCGNOB_6	24591	25184	STR_RS05880	0.0	Capsule	Immune modulation	91.75	100.00	WP_011226149
NHBCGNOB_6	24591	25184	STER_RS06030	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
NHBCGNOB_6	24591	25184	STU_RS15260	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
NHBCGNOB_6	198022	198753	STER_RS05315	0.0	Capsule	Immune modulation	91.53	100.00	WP_011681176
NHBCGNOB_6	23722	24591	rfbA	0.0	Capsule	Immune modulation	91.38	100.00	WP_011681286
NHBCGNOB_6	306314	307971	fbp54	0.0	FBPs	Adherence	91.14	99.88	WP_011227179
NHBCGNOB_6	198022	198753	STR_RS05260	0.0	Capsule	Immune modulation	90.98	100.00	WP_011227248
NHBCGNOB_13	20713	21552	cbpD	0.0	Autolysin	Exoenzyme	90.95	100.00	WP_011226733
NHBCGNOB_7	15355	16365	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
NHBCGNOB_11	158150	159453	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
NHBCGNOB_6	198762	199454	STR_RS05255	0.0	Capsule	Immune modulation	88.04	99.86	WP_011227247
NHBCGNOB_6	198762	199454	STU_RS14640	0.0	Capsule	Immune modulation	88.04	99.86	WP_011226047
NHBCGNOB_6	198762	199454	STER_RS05310	0.0	Capsule	Immune modulation	87.46	99.86	WP_011681175
NHBCGNOB_6	453209	453970	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
NHBCGNOB_6	25387	26433	rfbB	0.0	Capsule	Immune modulation	83.97	99.90	WP_002263087
NHBCGNOB_10	1916	3199	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
NHBCGNOB_6	210701	211286	SPD_RS01775	1.52e-146	Capsule	Immune modulation	82.96	96.53	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NHBCGNOB_6	456658	457641	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.34	100.00	AAK75326
NHBCGNOB_6	445075	444002	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
NHBCGNOB_7	140315	138009	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
NHBCGNOB_6	582399	583880	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
NHBCGNOB_6	426015	423769	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
NHBCGNOB_8	216298	217266	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
NHBCGNOB_13	35973	35002	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
NHBCGNOB_11	1821	91	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
NHBCGNOB_7	271509	272660	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
NHBCGNOB_7	299870	301858	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
NHBCGNOB_9	25875	27353	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
NHBCGNOB_11	159453	158152	Eno	0.0	enolase	86.44	99.77	ABP90468
NHBCGNOB_9	41248	43140	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
NHBCGNOB_13	2036	945	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
NHBCGNOB_6	420847	422556	PGM	0.0	phosphoglucomutase	84.59	99.65	ACH87041
NHBCGNOB_9	217362	216352	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
NHBCGNOB_6	291850	293211	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
NHBCGNOB_11	173869	172979	bglB	1.12e-177	putative phospho--glucosidase	87.54	99.66	AAK33487
NHBCGNOB_6	378465	379415	SP_0676	8.86e-170	transcription facot	81.39	98.45	AAK74821
NHBCGNOB_6	423579	422722	metF	8.40e-169	methionine biosynthesis enzymes	87.41	99.31	AAK74739
NHBCGNOB_6	150895	151599	covR	3.19e-126	responder protein	85.53	100.00	AAK71319
NHBCGNOB_6	519798	519127	rr01	4.99e-126	response regulator	84.38	99.56	CAB54566
NHBCGNOB_6	416880	416209	ciaR	8.23e-125	two component system response regulator	86.16	99.12	AIK75708
NHBCGNOB_6	416880	416212	CiaR	6.19e-124	two-component response regulator	87.00	99.55	AAK74935
NHBCGNOB_10	152442	153128	CovR	4.50e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
NHBCGNOB_6	150895	151599	walR	7.24e-120	DNA-binding response regulator	82.13	100.00	ANC99504
NHBCGNOB_13	771	376	SpxA2	3.95e-76	transcriptional regulator	91.67	100.00	ERL21461
NHBCGNOB_6	280379	279978	SpxA1	1.83e-69	transcriptional regulator	82.84	100.00	ERL19273
NHBCGNOB_12	6516	6112	GrpE	8.14e-68	protein grpE	82.96	78.82	ABP89267
NHBCGNOB_10	175653	175940	spr0479	5.45e-48	essential gene	85.42	98.97	AAK99283
NHBCGNOB_8	145199	145453	spr1327	1.23e-44	essential gene	92.94	100.00	AAL00131
NHBCGNOB_9	90329	90066	spr0175	1.27e-42	pathogenitcity related	85.23	100.00	AAK98979
NHBCGNOB_9	89505	89239	spr0177	2.83e-41	essential gene	83.15	88.12	AAK98981
NHBCGNOB_10	3366	3857	RopE (M5005_Spy_1611)	9.96e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
NHBCGNOB_7	140315	138015	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
NHBCGNOB_9	180924	181943	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451