Genome ID：GCA_028325885.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	34	40.55

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
BIIGPAPK_21	70496	71713	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
BIIGPAPK_21	68913	70376	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
BIIGPAPK_21	70499	71713	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
BIIGPAPK_21	68916	70376	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
BIIGPAPK_24	128563	129414	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
BIIGPAPK_11	256816	257556	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
BIIGPAPK_11	256816	257556	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
BIIGPAPK_11	257613	258980	STU_RS14630	0.0	Capsule	Immune modulation	93.93	100.00	WP_011226045
BIIGPAPK_11	256816	257551	STR_RS05250	0.0	Capsule	Immune modulation	93.89	98.13	WP_011227246
BIIGPAPK_24	130515	131786	STU_RS16265	0.0	Capsule	Immune modulation	93.79	99.76	WP_011226331
BIIGPAPK_11	253913	255373	STER_RS05320	0.0	Capsule	Immune modulation	93.71	99.93	WP_011681177
BIIGPAPK_11	253913	255373	STU_RS14650	0.0	Capsule	Immune modulation	93.63	100.14	WP_011226049
BIIGPAPK_11	257613	258978	STER_RS05300	0.0	Capsule	Immune modulation	93.63	99.85	WP_011681173
BIIGPAPK_11	253913	255373	STR_RS05265	0.0	Capsule	Immune modulation	92.88	100.14	WP_041827043
BIIGPAPK_24	139629	141413	STU_RS16230	0.0	Capsule	Immune modulation	92.72	100.00	WP_011226325
BIIGPAPK_24	137361	138566	STU_RS16240	0.0	Capsule	Immune modulation	92.62	100.00	WP_011226326
BIIGPAPK_24	135612	136568	STU_RS16250	0.0	Capsule	Immune modulation	92.48	100.00	WP_011226328
BIIGPAPK_24	134467	135615	STU_RS16255	0.0	Capsule	Immune modulation	92.34	100.00	WP_041828290
BIIGPAPK_24	136552	137361	STU_RS16245	0.0	Capsule	Immune modulation	92.23	99.88	WP_002948020
BIIGPAPK_11	255374	256105	STU_RS14645	0.0	Capsule	Immune modulation	91.67	100.00	WP_011226048
BIIGPAPK_24	138586	139632	STU_RS16235	0.0	Capsule	Immune modulation	91.57	99.43	WP_002948022
BIIGPAPK_11	85426	86295	rfbA	0.0	Capsule	Immune modulation	91.49	100.00	WP_011681286
BIIGPAPK_11	255374	256105	STER_RS05315	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681176
BIIGPAPK_23	66964	68621	fbp54	0.0	FBPs	Adherence	91.20	99.88	WP_011227179
BIIGPAPK_11	86295	86888	STR_RS05880	0.0	Capsule	Immune modulation	90.74	100.00	WP_011226149
BIIGPAPK_11	255374	256105	STR_RS05260	0.0	Capsule	Immune modulation	90.71	100.00	WP_011227248
BIIGPAPK_11	86295	86888	STER_RS06030	0.0	Capsule	Immune modulation	90.57	100.00	WP_011226149
BIIGPAPK_11	86295	86888	STU_RS15260	0.0	Capsule	Immune modulation	90.57	100.00	WP_011226149
BIIGPAPK_1	22228	22989	cbpD	0.0	Autolysin	Exoenzyme	90.29	90.71	WP_011226733
BIIGPAPK_11	256114	256806	STR_RS05255	0.0	Capsule	Immune modulation	88.62	99.86	WP_011227247
BIIGPAPK_11	256114	256806	STU_RS14640	0.0	Capsule	Immune modulation	88.62	99.86	WP_011226047
BIIGPAPK_25	13477	14487	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
BIIGPAPK_11	256114	256806	STER_RS05310	0.0	Capsule	Immune modulation	87.46	99.86	WP_011681175
BIIGPAPK_21	95771	97074	eno	0.0	Streptococcal enolase	Exoenzyme	87.25	99.54	WP_000022832
BIIGPAPK_23	205575	206336	srtA	0.0	Sortase A	Exoenzyme	84.67	99.87	-
BIIGPAPK_4	16988	18271	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
BIIGPAPK_11	87092	88138	rfbB	0.0	Capsule	Immune modulation	80.33	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
BIIGPAPK_23	197440	196367	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
BIIGPAPK_23	209025	210008	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.04	100.00	AAK75326
BIIGPAPK_25	140293	137987	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
BIIGPAPK_28	43985	45466	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
BIIGPAPK_23	178380	176134	metE	0.0	methionine biosynthesis enzymes	92.52	100.00	AAK74738
BIIGPAPK_21	186902	185934	spr0084	0.0	pathogenitcity related	92.26	98.48	AAK98888
BIIGPAPK_1	37410	36439	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
BIIGPAPK_23	268418	261855	PrtA	0.0	serine protease	90.05	101.96	ABJ55268
BIIGPAPK_11	60039	61769	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
BIIGPAPK_24	87919	89070	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
BIIGPAPK_24	116519	118507	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
BIIGPAPK_26	176152	174674	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
BIIGPAPK_21	97074	95773	Eno	0.0	enolase	86.44	99.77	ABP90468
BIIGPAPK_26	160794	158902	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
BIIGPAPK_23	173215	174924	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
BIIGPAPK_1	2093	1002	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
BIIGPAPK_26	28541	29551	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
BIIGPAPK_23	41193	42554	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
BIIGPAPK_21	111481	110591	bglB	3.68e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
BIIGPAPK_23	132524	133474	SP_0676	3.39e-170	transcription facot	81.39	98.45	AAK74821
BIIGPAPK_23	175947	175090	metF	6.89e-169	methionine biosynthesis enzymes	87.76	99.31	AAK74739
BIIGPAPK_8	8389	9060	rr01	2.66e-128	response regulator	84.82	99.56	CAB54566
BIIGPAPK_11	208503	209207	covR	1.27e-126	responder protein	85.53	100.00	AAK71319
BIIGPAPK_23	169248	168577	ciaR	2.62e-125	two component system response regulator	86.16	99.12	AIK75708
BIIGPAPK_23	169248	168580	CiaR	4.84e-125	two-component response regulator	87.44	99.55	AAK74935
BIIGPAPK_11	208503	209207	walR	2.88e-120	DNA-binding response regulator	82.13	100.00	ANC99504
BIIGPAPK_27	53855	53169	CovR	3.85e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
BIIGPAPK_1	827	432	SpxA2	4.09e-76	transcriptional regulator	91.67	100.00	ERL21461
BIIGPAPK_23	29727	29326	SpxA1	5.61e-70	transcriptional regulator	82.84	100.00	ERL19273
BIIGPAPK_2	24973	25386	GrpE	2.43e-68	protein grpE	81.88	80.59	ABP89267
BIIGPAPK_27	30647	30360	spr0479	3.73e-48	essential gene	85.42	98.97	AAK99283
BIIGPAPK_21	225698	225444	spr1327	1.28e-44	essential gene	92.94	100.00	AAL00131
BIIGPAPK_26	117498	117761	spr0175	9.46e-43	pathogenitcity related	85.23	100.00	AAK98979
BIIGPAPK_26	118322	118588	spr0177	2.10e-41	essential gene	83.15	88.12	AAK98981
BIIGPAPK_4	16821	16330	RopE (M5005_Spy_1611)	9.60e-74	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
BIIGPAPK_25	140293	137993	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
BIIGPAPK_26	64964	63945	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451