Genome ID：GCA_035591855.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	15	35	38.13

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
FLHEMEON_30	65178	66395	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
FLHEMEON_30	63595	65058	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
FLHEMEON_30	65181	66395	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
FLHEMEON_30	63598	65058	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
FLHEMEON_11	69315	70166	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
FLHEMEON_3	7646	9106	STU_RS14650	0.0	Capsule	Immune modulation	93.77	100.14	WP_011226049
FLHEMEON_3	7646	9106	STER_RS05320	0.0	Capsule	Immune modulation	93.70	100.00	WP_011681177
FLHEMEON_3	11347	12714	STU_RS14630	0.0	Capsule	Immune modulation	93.06	100.00	WP_011226045
FLHEMEON_3	11347	12712	STER_RS05300	0.0	Capsule	Immune modulation	92.90	99.85	WP_011681173
FLHEMEON_3	7646	9106	STR_RS05265	0.0	Capsule	Immune modulation	92.88	100.14	WP_041827043
FLHEMEON_43	82154	82747	STR_RS05880	0.0	Capsule	Immune modulation	92.09	100.00	WP_011226149
FLHEMEON_43	82154	82747	STER_RS06030	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
FLHEMEON_43	82154	82747	STU_RS15260	0.0	Capsule	Immune modulation	91.92	100.00	WP_011226149
FLHEMEON_3	9107	9838	STU_RS14645	0.0	Capsule	Immune modulation	91.80	100.00	WP_011226048
FLHEMEON_21	58194	58955	srtA	0.0	Sortase A	Exoenzyme	91.73	100.00	-
FLHEMEON_43	81285	82154	rfbA	0.0	Capsule	Immune modulation	91.49	100.00	WP_011681286
FLHEMEON_3	9107	9838	STER_RS05315	0.0	Capsule	Immune modulation	91.39	100.00	WP_011681176
FLHEMEON_3	9107	9838	STR_RS05260	0.0	Capsule	Immune modulation	90.85	100.00	WP_011227248
FLHEMEON_3	10549	11289	STER_RS05305	0.0	Capsule	Immune modulation	90.84	99.87	WP_011681174
FLHEMEON_21	205734	207392	fbp54	0.0	FBPs	Adherence	90.42	99.94	WP_011227179
FLHEMEON_3	10549	11289	STU_RS14635	0.0	Capsule	Immune modulation	89.89	99.87	WP_011226046
FLHEMEON_3	10549	11284	STR_RS05250	0.0	Capsule	Immune modulation	89.55	98.00	WP_011227246
FLHEMEON_11	396152	397162	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
FLHEMEON_30	95432	96735	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
FLHEMEON_3	9847	10539	STU_RS14640	0.0	Capsule	Immune modulation	85.45	99.86	WP_011226047
FLHEMEON_3	9847	10539	STR_RS05255	0.0	Capsule	Immune modulation	85.16	99.86	WP_011227247
FLHEMEON_3	9847	10539	STER_RS05310	0.0	Capsule	Immune modulation	84.87	99.86	WP_011681175
FLHEMEON_44	31829	32725	cbpD	0.0	Autolysin	Exoenzyme	84.78	93.09	WP_082302295
FLHEMEON_33	203315	204598	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
FLHEMEON_43	83019	84065	rfbB	0.0	Capsule	Immune modulation	80.13	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
FLHEMEON_21	55506	54523	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.34	100.00	AAK75326
FLHEMEON_21	71768	72841	MntE	0.0	manganese homeostasis	95.25	99.72	ABF32167
FLHEMEON_11	247099	249405	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
FLHEMEON_38	76733	75252	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
FLHEMEON_30	186229	185261	spr0084	0.0	pathogenitcity related	92.57	98.48	AAK98888
FLHEMEON_21	90823	93069	metE	0.0	methionine biosynthesis enzymes	92.52	100.00	AAK74738
FLHEMEON_4	38984	38013	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
FLHEMEON_43	55906	57636	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
FLHEMEON_11	113608	112457	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
FLHEMEON_11	85126	83138	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
FLHEMEON_1	6917	8395	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
FLHEMEON_30	96735	95434	Eno	0.0	enolase	86.44	99.77	ABP90468
FLHEMEON_1	22280	24172	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
FLHEMEON_21	95988	94279	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
FLHEMEON_4	1199	108	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
FLHEMEON_42	28752	29762	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
FLHEMEON_21	220899	219538	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
FLHEMEON_30	111154	110264	bglB	2.61e-177	putative phospho--glucosidase	87.20	99.66	AAK33487
FLHEMEON_21	135117	134179	SP_0676	2.46e-169	transcription facot	81.79	97.20	AAK74821
FLHEMEON_21	93256	94113	metF	7.24e-169	methionine biosynthesis enzymes	87.76	99.31	AAK74739
FLHEMEON_44	38874	38194	NisR	6.35e-133	two-component signal-transduction systems	94.71	100.00	ABP89873
FLHEMEON_44	38206	37502	NisK	1.55e-131	two-component signal-transduction systems	91.06	100.00	ABP89872
FLHEMEON_45	51841	52545	covR	3.99e-127	responder protein	85.53	100.00	AAK71319
FLHEMEON_38	142676	143347	rr01	1.68e-125	response regulator	83.48	99.56	CAB54566
FLHEMEON_21	99957	100628	ciaR	2.75e-125	two component system response regulator	86.16	99.12	AIK75708
FLHEMEON_21	99957	100625	CiaR	5.09e-125	two-component response regulator	87.44	99.55	AAK74935
FLHEMEON_45	51841	52545	walR	9.07e-121	DNA-binding response regulator	82.13	100.00	ANC99504
FLHEMEON_33	53642	52956	CovR	4.51e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
FLHEMEON_14	209	604	SpxA2	1.26e-84	transcriptional regulator	91.67	100.00	ERL21461
FLHEMEON_21	232364	232765	SpxA1	1.73e-69	transcriptional regulator	82.09	100.00	ERL19273
FLHEMEON_2	42869	43282	GrpE	3.83e-68	protein grpE	81.88	80.59	ABP89267
FLHEMEON_33	30435	30148	spr0479	5.46e-48	essential gene	85.42	98.97	AAK99283
FLHEMEON_30	220257	220003	spr1327	1.10e-44	essential gene	92.94	100.00	AAL00131
FLHEMEON_42	151357	151620	spr0175	8.52e-43	pathogenitcity related	85.23	100.00	AAK98979
FLHEMEON_42	152181	152447	spr0177	1.89e-41	essential gene	83.15	88.12	AAK98981
FLHEMEON_33	203148	202657	RopE (M5005_Spy_1611)	9.98e-73	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
FLHEMEON_11	247099	249399	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
FLHEMEON_42	65183	64164	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451