Genome ID：GCA_035591915.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	17	34	38.07

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
FLPIENJJ_57	17746	18963	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
FLPIENJJ_57	16163	17626	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
FLPIENJJ_57	17749	18963	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
FLPIENJJ_57	16166	17626	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
FLPIENJJ_55	165148	165999	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
FLPIENJJ_58	1946	2677	STER_RS05315	0.0	Capsule	Immune modulation	94.81	100.00	WP_011681176
FLPIENJJ_55	168423	169138	STER_RS07085	0.0	Capsule	Immune modulation	94.55	99.86	WP_011681442
FLPIENJJ_58	1946	2677	STU_RS14645	0.0	Capsule	Immune modulation	94.54	100.00	WP_011226048
FLPIENJJ_58	1946	2677	STR_RS05260	0.0	Capsule	Immune modulation	94.13	100.00	WP_011227248
FLPIENJJ_55	169484	170254	STER_RS07075	0.0	Capsule	Immune modulation	92.48	99.23	WP_011681440
FLPIENJJ_55	166118	167376	STER_RS07100	0.0	Capsule	Immune modulation	92.22	99.92	WP_011681445
FLPIENJJ_1	92221	92814	STR_RS05880	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
FLPIENJJ_1	92221	92814	STER_RS06030	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
FLPIENJJ_1	92221	92814	STU_RS15260	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
FLPIENJJ_58	485	1945	STER_RS05320	0.0	Capsule	Immune modulation	90.92	99.86	WP_011681177
FLPIENJJ_58	485	1945	STU_RS14650	0.0	Capsule	Immune modulation	90.78	100.00	WP_011226049
FLPIENJJ_58	118127	119784	fbp54	0.0	FBPs	Adherence	90.36	99.88	WP_011227179
FLPIENJJ_58	485	1945	STR_RS05265	0.0	Capsule	Immune modulation	89.97	100.00	WP_041827043
FLPIENJJ_58	2686	3378	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
FLPIENJJ_58	2686	3378	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
FLPIENJJ_58	2686	3378	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
FLPIENJJ_57	55431	56734	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
FLPIENJJ_55	72390	73229	cbpD	0.0	Autolysin	Exoenzyme	87.87	99.88	WP_011226733
FLPIENJJ_14	13424	14437	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
FLPIENJJ_44	37976	38737	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
FLPIENJJ_1	90905	91951	rfbB	0.0	Capsule	Immune modulation	83.40	99.90	WP_002263087
FLPIENJJ_6	47364	48647	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
FLPIENJJ_1	92814	93683	rfbA	0.0	Capsule	Immune modulation	80.39	99.77	WP_002904719
FLPIENJJ_58	3388	4058	STU_RS14635	7.27e-148	Capsule	Immune modulation	80.98	90.28	WP_011226046
FLPIENJJ_58	3388	4058	STER_RS05305	3.38e-146	Capsule	Immune modulation	80.83	90.28	WP_011681174

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
FLPIENJJ_44	35287	34304	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
FLPIENJJ_44	46873	47946	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
FLPIENJJ_11	18374	16068	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
FLPIENJJ_44	66413	68659	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
FLPIENJJ_51	95501	96982	SPD_0310	0.0	UPF0371 protein SPD_0310	92.92	100.00	ABJ54480
FLPIENJJ_11	229484	230452	spr0084	0.0	pathogenitcity related	92.26	98.48	AAK98888
FLPIENJJ_19	1079	108	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
FLPIENJJ_15	9592	11322	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
FLPIENJJ_55	150014	152002	uvrB	0.0	excinuclease ABC, B subunit	89.74	100.00	AE014259_2
FLPIENJJ_11	153334	154485	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
FLPIENJJ_22	7293	8771	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
FLPIENJJ_57	56734	55433	Eno	0.0	enolase	86.44	99.77	ABP90468
FLPIENJJ_22	23073	24965	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
FLPIENJJ_9	1213	122	recA	0.0	DNA recombination and repair	84.91	95.36	AAL00560
FLPIENJJ_44	71577	69868	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
FLPIENJJ_58	104365	105726	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
FLPIENJJ_22	178604	177594	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
FLPIENJJ_57	71144	70254	bglB	1.47e-177	putative phospho--glucosidase	87.20	99.66	AAK33487
FLPIENJJ_44	68849	69706	metF	6.26e-170	methionine biosynthesis enzymes	87.76	99.31	AAK74739
FLPIENJJ_44	113114	112176	SP_0676	1.29e-168	transcription facot	81.47	97.20	AAK74821
FLPIENJJ_3	27439	28296	mtsA	1.14e-151	substrate-binding lipoprotein of manganese transporter	80.14	92.86	AIK76191
FLPIENJJ_10	2303	3007	covR	1.52e-127	responder protein	85.53	100.00	AAK71319
FLPIENJJ_51	29974	29303	rr01	1.54e-126	response regulator	84.82	99.56	CAB54566
FLPIENJJ_44	76242	76913	ciaR	1.81e-125	two component system response regulator	86.16	99.12	AIK75708
FLPIENJJ_44	76242	76910	CiaR	3.35e-125	two-component response regulator	87.44	99.55	AAK74935
FLPIENJJ_10	2303	3007	walR	3.45e-121	DNA-binding response regulator	82.13	100.00	ANC99504
FLPIENJJ_2	36470	35784	CovR	8.73e-121	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
FLPIENJJ_28	204	599	SpxA2	3.56e-85	transcriptional regulator	91.67	100.00	ERL21461
FLPIENJJ_58	92907	92506	SpxA1	7.82e-70	transcriptional regulator	82.09	100.00	ERL19273
FLPIENJJ_8	6424	6011	GrpE	3.06e-68	protein grpE	81.88	80.59	ABP89267
FLPIENJJ_2	13265	12978	spr0479	5.71e-48	essential gene	85.42	98.97	AAK99283
FLPIENJJ_11	195817	196071	spr1327	7.57e-46	essential gene	94.12	100.00	AAL00131
FLPIENJJ_22	87929	87666	spr0175	1.08e-42	pathogenitcity related	85.23	100.00	AAK98979
FLPIENJJ_22	87104	86838	spr0177	2.39e-41	essential gene	83.15	88.12	AAK98981
FLPIENJJ_6	47197	46706	RopE (M5005_Spy_1611)	2.43e-73	probable DNA-directed RNA polymerase subunit delta	83.54	85.86	AAK34603
FLPIENJJ_11	18374	16074	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
FLPIENJJ_22	142190	143209	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451
FLPIENJJ_44	179660	180199	pnuC	1.06e-92	NAD salvage pathway importer	82.78	66.91	AAK75931