Genome ID：GCA_041431825.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
1	20	35	40.32

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
HLKJGPCH_3	148133	150052	tet(M)	ARO:3000186	tet(M)	90.77	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
HLKJGPCH_3	148133	150051	tet(M)	Doxycycline, Tetracycline, Minocycline	95.15	99.95	JN846696

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
HLKJGPCH_3	148133	150049	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	BLASTX	98.28	100.00	WP_011860841.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HLKJGPCH_5	91647	92498	rfbD	0.0	Capsule	Immune modulation	95.31	100.00	WP_014621820
HLKJGPCH_15	24306	25037	STR_RS05260	0.0	Capsule	Immune modulation	93.99	100.00	WP_011227248
HLKJGPCH_15	24306	25037	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
HLKJGPCH_15	24306	25037	STU_RS14645	0.0	Capsule	Immune modulation	93.31	100.00	WP_011226048
HLKJGPCH_5	84563	86319	STU_RS16230	0.0	Capsule	Immune modulation	92.60	98.43	WP_011226325
HLKJGPCH_5	89369	90325	STU_RS16250	0.0	Capsule	Immune modulation	92.48	100.00	WP_011226328
HLKJGPCH_5	88576	89385	STU_RS16245	0.0	Capsule	Immune modulation	92.23	99.88	WP_002948020
HLKJGPCH_5	87371	88576	STU_RS16240	0.0	Capsule	Immune modulation	92.21	100.00	WP_011226326
HLKJGPCH_5	90322	91470	STU_RS16255	0.0	Capsule	Immune modulation	91.56	99.91	WP_041828290
HLKJGPCH_6	35700	36293	STR_RS05880	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
HLKJGPCH_15	25038	26498	STER_RS05320	0.0	Capsule	Immune modulation	91.19	99.86	WP_011681177
HLKJGPCH_5	86316	87350	STU_RS16235	0.0	Capsule	Immune modulation	91.10	99.15	WP_002948022
HLKJGPCH_6	35700	36293	STER_RS06030	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
HLKJGPCH_6	35700	36293	STU_RS15260	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
HLKJGPCH_2	143179	144837	fbp54	0.0	FBPs	Adherence	91.08	99.94	WP_011227179
HLKJGPCH_15	25038	26498	STU_RS14650	0.0	Capsule	Immune modulation	90.78	100.00	WP_011226049
HLKJGPCH_15	25038	26498	STR_RS05265	0.0	Capsule	Immune modulation	90.10	100.00	WP_041827043
HLKJGPCH_15	23605	24297	STU_RS14640	0.0	Capsule	Immune modulation	90.04	100.00	WP_011226047
HLKJGPCH_15	23605	24297	STR_RS05255	0.0	Capsule	Immune modulation	89.75	100.00	WP_011227247
HLKJGPCH_15	23605	24297	STER_RS05310	0.0	Capsule	Immune modulation	89.61	100.00	WP_011681175
HLKJGPCH_17	16278	17117	cbpD	0.0	Autolysin	Exoenzyme	89.06	99.88	WP_011226733
HLKJGPCH_14	1	1302	eno	0.0	Streptococcal enolase	Exoenzyme	88.23	99.39	WP_000022832
HLKJGPCH_1	403344	404357	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
HLKJGPCH_19	17594	18355	srtA	0.0	Sortase A	Exoenzyme	84.40	99.87	-
HLKJGPCH_6	36563	37609	rfbB	0.0	Capsule	Immune modulation	83.40	99.90	WP_002263087
HLKJGPCH_4	187825	189108	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753
HLKJGPCH_6	34831	35700	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
HLKJGPCH_15	22925	23595	STU_RS14635	7.36e-147	Capsule	Immune modulation	80.83	90.28	WP_011226046
HLKJGPCH_15	22925	23595	STER_RS05305	3.42e-145	Capsule	Immune modulation	80.68	90.28	WP_011681174

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HLKJGPCH_19	21044	22027	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.95	100.00	AAK75326
HLKJGPCH_19	9458	8385	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
HLKJGPCH_1	275018	277324	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.15	99.22	AAK74619
HLKJGPCH_1	54729	53761	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
HLKJGPCH_2	10077	12323	metE	0.0	methionine biosynthesis enzymes	93.06	100.00	AAK74738
HLKJGPCH_3	106850	108331	SPD_0310	0.0	UPF0371 protein SPD_0310	92.51	100.00	ABJ54480
HLKJGPCH_38	3823	4794	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
HLKJGPCH_3	17282	10809	PrtA	0.0	serine protease	91.35	100.61	ABJ55268
HLKJGPCH_6	9454	11184	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	90.12	100.00	AAK34199
HLKJGPCH_1	129381	128230	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
HLKJGPCH_5	104685	102697	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
HLKJGPCH_10	42934	41456	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
HLKJGPCH_14	1302	1	Eno	0.0	enolase	86.21	99.77	ABP90468
HLKJGPCH_10	27591	25699	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.74	98.90	ABP91129
HLKJGPCH_29	11943	13034	recA	0.0	DNA recombination and repair	84.91	95.36	AAL00560
HLKJGPCH_2	15245	13536	PGM	0.0	phosphoglucomutase	84.59	99.65	ACH87041
HLKJGPCH_7	7420	8430	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
HLKJGPCH_2	158766	157405	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
HLKJGPCH_14	15712	14822	bglB	4.28e-179	putative phospho--glucosidase	87.88	99.66	AAK33487
HLKJGPCH_2	55243	54293	SP_0676	2.58e-170	transcription facot	81.39	98.45	AAK74821
HLKJGPCH_2	12513	13370	metF	1.69e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
HLKJGPCH_11	10934	11791	mtsA	5.96e-152	substrate-binding lipoprotein of manganese transporter	80.14	92.86	AIK76191
HLKJGPCH_20	4932	5636	covR	1.35e-127	responder protein	85.53	100.00	AAK71319
HLKJGPCH_3	35136	34465	rr01	1.39e-126	response regulator	84.38	99.56	CAB54566
HLKJGPCH_2	19910	20581	ciaR	2.24e-125	two component system response regulator	86.16	99.12	AIK75708
HLKJGPCH_2	19910	20578	CiaR	4.14e-125	two-component response regulator	87.44	99.55	AAK74935
HLKJGPCH_20	4932	5636	walR	1.20e-120	DNA-binding response regulator	81.70	100.00	ANC99504
HLKJGPCH_4	38221	37535	CovR	1.60e-120	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
HLKJGPCH_47	128	523	SpxA2	6.63e-86	transcriptional regulator	91.67	100.00	ERL21461
HLKJGPCH_2	170234	170635	SpxA1	1.49e-69	transcriptional regulator	82.09	100.00	ERL19273
HLKJGPCH_12	33364	33777	GrpE	3.11e-68	protein grpE	81.88	80.59	ABP89267
HLKJGPCH_4	15015	14728	spr0479	5.05e-48	essential gene	85.42	98.97	AAK99283
HLKJGPCH_1	86215	85961	spr1327	1.32e-45	essential gene	94.12	100.00	AAL00131
HLKJGPCH_7	97194	97457	spr0175	5.08e-43	pathogenitcity related	85.23	100.00	AAK98979
HLKJGPCH_7	98019	98285	spr0177	1.13e-41	essential gene	83.15	88.12	AAK98981
HLKJGPCH_4	187667	187167	RopE (M5005_Spy_1611)	2.16e-74	probable DNA-directed RNA polymerase subunit delta	82.64	87.43	AAK34603
HLKJGPCH_1	275018	277318	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.97	98.08	MYN69560
HLKJGPCH_7	44068	43049	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451