Genome ID：GCA_041431895.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	18	33	37.64

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
MLFHLGCP_1	65342	66805	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	99.93	100.00	AF274302
MLFHLGCP_1	66925	68141	mef(A)	Erythromycin, Azithromycin	99.92	99.92	U83667

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
MLFHLGCP_1	65345	66805	msr(D)	ABC-F type ribosomal protection protein Msr(D)	BLASTX	99.79	100.00	WP_000420313.1
MLFHLGCP_1	66928	68136	mef(A)	macrolide efflux MFS transporter Mef(A)	BLASTX	99.26	99.51	WP_000417519.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
MLFHLGCP_2	48522	49982	STER_RS05320	0.0	Capsule	Immune modulation	97.26	100.00	WP_011681177
MLFHLGCP_2	48522	49982	STU_RS14650	0.0	Capsule	Immune modulation	96.92	100.21	WP_011226049
MLFHLGCP_9	23061	23777	STER_RS07085	0.0	Capsule	Immune modulation	96.79	100.00	WP_011681442
MLFHLGCP_2	48522	49982	STR_RS05265	0.0	Capsule	Immune modulation	96.37	100.21	WP_041827043
MLFHLGCP_2	52222	53587	STER_RS05300	0.0	Capsule	Immune modulation	94.88	99.85	WP_011681173
MLFHLGCP_2	52222	53589	STU_RS14630	0.0	Capsule	Immune modulation	94.52	100.00	WP_011226045
MLFHLGCP_2	51425	52165	STER_RS05305	0.0	Capsule	Immune modulation	94.06	100.00	WP_011681174
MLFHLGCP_9	18065	18916	rfbD	0.0	Capsule	Immune modulation	93.90	100.00	WP_014621820
MLFHLGCP_2	49983	50714	STER_RS05315	0.0	Capsule	Immune modulation	93.85	100.00	WP_011681176
MLFHLGCP_2	49983	50714	STU_RS14645	0.0	Capsule	Immune modulation	93.72	100.00	WP_011226048
MLFHLGCP_2	51425	52165	STU_RS14635	0.0	Capsule	Immune modulation	93.12	100.00	WP_011226046
MLFHLGCP_2	49983	50714	STR_RS05260	0.0	Capsule	Immune modulation	93.03	100.00	WP_011227248
MLFHLGCP_2	51425	52160	STR_RS05250	0.0	Capsule	Immune modulation	92.80	98.13	WP_011227246
MLFHLGCP_9	24123	24893	STER_RS07075	0.0	Capsule	Immune modulation	92.75	99.10	WP_011681440
MLFHLGCP_6	110641	111234	STR_RS05880	0.0	Capsule	Immune modulation	91.58	100.00	WP_011226149
MLFHLGCP_6	110641	111234	STER_RS06030	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
MLFHLGCP_6	110641	111234	STU_RS15260	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
MLFHLGCP_6	111234	112103	rfbA	0.0	Capsule	Immune modulation	91.03	100.00	WP_011681286
MLFHLGCP_10	23417	24256	cbpD	0.0	Autolysin	Exoenzyme	90.62	99.88	WP_011226733
MLFHLGCP_2	159157	160815	fbp54	0.0	FBPs	Adherence	90.24	99.94	WP_011227179
MLFHLGCP_3	273384	274394	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.84	99.80	WP_002986042
MLFHLGCP_2	50723	51415	STR_RS05255	0.0	Capsule	Immune modulation	88.47	99.86	WP_011227247
MLFHLGCP_2	50723	51415	STU_RS14640	0.0	Capsule	Immune modulation	88.47	99.86	WP_011226047
MLFHLGCP_1	92137	93440	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
MLFHLGCP_2	50723	51415	STER_RS05310	0.0	Capsule	Immune modulation	87.75	99.86	WP_011681175
MLFHLGCP_6	109324	110370	rfbB	0.0	Capsule	Immune modulation	84.06	99.90	WP_002263087
MLFHLGCP_2	314245	315006	srtA	0.0	Sortase A	Exoenzyme	83.90	99.74	-
MLFHLGCP_4	2499	3782	tig/ropA	0.0	Trigger factor	Stress survival	80.93	99.53	WP_000107753
MLFHLGCP_2	61741	62324	SPD_RS01775	2.13e-157	Capsule	Immune modulation	84.10	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
MLFHLGCP_2	306115	305042	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
MLFHLGCP_2	317694	318668	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.00	99.09	AAK75326
MLFHLGCP_3	151332	153638	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.54	99.22	AAK74619
MLFHLGCP_8	83169	84650	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
MLFHLGCP_1	190743	189775	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
MLFHLGCP_2	287055	284809	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
MLFHLGCP_10	43180	42209	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
MLFHLGCP_6	137488	135758	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
MLFHLGCP_3	5014	3863	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
MLFHLGCP_9	4811	6799	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
MLFHLGCP_5	25573	27051	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
MLFHLGCP_1	93440	92139	Eno	0.0	enolase	86.44	99.77	ABP90468
MLFHLGCP_5	40922	42814	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.42	98.90	ABP91129
MLFHLGCP_2	281890	283599	PGM	0.0	phosphoglucomutase	84.94	99.65	ACH87041
MLFHLGCP_10	2056	965	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
MLFHLGCP_5	184851	183841	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
MLFHLGCP_2	143595	144956	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
MLFHLGCP_1	107846	106956	bglB	4.67e-178	putative phospho--glucosidase	87.88	99.66	AAK33487
MLFHLGCP_2	284622	283765	metF	1.65e-169	methionine biosynthesis enzymes	88.11	99.31	AAK74739
MLFHLGCP_2	242549	243511	SP_0676	2.98e-169	transcription facot	80.69	99.69	AAK74821
MLFHLGCP_8	27273	26602	rr01	1.14e-126	response regulator	84.38	99.56	CAB54566
MLFHLGCP_2	2243	2947	covR	1.39e-125	responder protein	85.11	100.00	AAK71319
MLFHLGCP_2	277922	277251	ciaR	1.63e-124	two component system response regulator	85.71	99.12	AIK75708
MLFHLGCP_2	277922	277254	CiaR	2.02e-124	two-component response regulator	87.00	99.55	AAK74935
MLFHLGCP_4	163004	163690	CovR	4.77e-120	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
MLFHLGCP_2	2243	2947	walR	2.23e-119	DNA-binding response regulator	81.70	100.00	ANC99504
MLFHLGCP_10	791	396	SpxA2	4.66e-76	transcriptional regulator	91.67	100.00	ERL21461
MLFHLGCP_2	132128	131727	SpxA1	6.92e-70	transcriptional regulator	82.84	100.00	ERL19273
MLFHLGCP_11	6137	5733	GrpE	6.47e-68	protein grpE	82.96	78.82	ABP89267
MLFHLGCP_4	186214	186501	spr0479	5.78e-48	essential gene	85.42	98.97	AAK99283
MLFHLGCP_1	232577	232323	spr1327	1.71e-44	essential gene	92.94	100.00	AAL00131
MLFHLGCP_5	71839	71576	spr0175	1.00e-42	pathogenitcity related	85.23	100.00	AAK98979
MLFHLGCP_5	71013	70747	spr0177	1.40e-41	essential gene	83.15	88.12	AAK98981
MLFHLGCP_4	3949	4440	RopE (M5005_Spy_1611)	1.06e-72	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
MLFHLGCP_3	151332	153632	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.36	98.08	MYN69560
MLFHLGCP_5	148407	149426	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451