Genome ID：GCA_046531385.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	16	28	32.31

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
HPCIBOKB_1	1490355	1491572	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
HPCIBOKB_1	1488707	1490170	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	99.25	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
HPCIBOKB_1	1490358	1491572	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
HPCIBOKB_1	1488710	1490170	msr(D)	ABC-F type ribosomal protection protein Msr(D)	BLASTX	98.97	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
HPCIBOKB_1	526442	527293	rfbD	0.0	Capsule	Immune modulation	94.48	100.00	WP_014621820
HPCIBOKB_1	1155374	1156834	STER_RS05320	0.0	Capsule	Immune modulation	93.98	100.00	WP_011681177
HPCIBOKB_1	1151768	1153135	STU_RS14630	0.0	Capsule	Immune modulation	93.93	100.00	WP_011226045
HPCIBOKB_1	1155374	1156834	STU_RS14650	0.0	Capsule	Immune modulation	93.84	100.14	WP_011226049
HPCIBOKB_1	1151770	1153135	STER_RS05300	0.0	Capsule	Immune modulation	93.78	99.85	WP_011681173
HPCIBOKB_1	1153191	1153931	STER_RS05305	0.0	Capsule	Immune modulation	93.52	100.00	WP_011681174
HPCIBOKB_1	1333166	1333759	STR_RS05880	0.0	Capsule	Immune modulation	93.27	100.00	WP_011226149
HPCIBOKB_1	1155374	1156834	STR_RS05265	0.0	Capsule	Immune modulation	93.22	100.14	WP_041827043
HPCIBOKB_1	1333166	1333759	STER_RS06030	0.0	Capsule	Immune modulation	93.10	100.00	WP_011226149
HPCIBOKB_1	1333166	1333759	STU_RS15260	0.0	Capsule	Immune modulation	93.10	100.00	WP_011226149
HPCIBOKB_1	1153191	1153931	STU_RS14635	0.0	Capsule	Immune modulation	92.98	100.00	WP_011226046
HPCIBOKB_1	1153196	1153931	STR_RS05250	0.0	Capsule	Immune modulation	92.53	98.13	WP_011227246
HPCIBOKB_1	1154642	1155373	STU_RS14645	0.0	Capsule	Immune modulation	92.35	100.00	WP_011226048
HPCIBOKB_1	1154642	1155373	STER_RS05315	0.0	Capsule	Immune modulation	91.67	100.00	WP_011681176
HPCIBOKB_1	1333759	1334628	rfbA	0.0	Capsule	Immune modulation	91.49	100.00	WP_011681286
HPCIBOKB_1	1154642	1155373	STR_RS05260	0.0	Capsule	Immune modulation	91.39	100.00	WP_011227248
HPCIBOKB_1	2124942	2125781	cbpD	0.0	Autolysin	Exoenzyme	90.95	100.00	WP_011226733
HPCIBOKB_1	1041147	1042805	fbp54	0.0	FBPs	Adherence	89.76	99.94	WP_011227179
HPCIBOKB_1	205431	206441	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.75	99.80	WP_002986042
HPCIBOKB_1	1153941	1154633	STR_RS05255	0.0	Capsule	Immune modulation	88.62	99.86	WP_011227247
HPCIBOKB_1	1153941	1154633	STU_RS14640	0.0	Capsule	Immune modulation	88.62	99.86	WP_011226047
HPCIBOKB_1	1519555	1520858	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
HPCIBOKB_1	1153941	1154633	STER_RS05310	0.0	Capsule	Immune modulation	86.89	99.86	WP_011681175
HPCIBOKB_1	901092	901812	srtA	0.0	Sortase A	Exoenzyme	84.49	94.49	-
HPCIBOKB_1	2026354	2027637	tig/ropA	0.0	Trigger factor	Stress survival	80.61	99.61	WP_000107753
HPCIBOKB_1	1331917	1332963	rfbB	0.0	Capsule	Immune modulation	80.36	99.90	WP_009659423
HPCIBOKB_1	1142026	1142609	SPD_RS01775	1.26e-156	Capsule	Immune modulation	84.10	96.20	WP_001819836
HPCIBOKB_1	531438	531907	STER_RS07085	0.0	Capsule	Immune modulation	95.32	65.41	WP_011681442

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
HPCIBOKB_1	896922	895948	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.31	99.09	AAK75326
HPCIBOKB_1	909948	911021	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
HPCIBOKB_1	333215	330909	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.28	99.22	AAK74619
HPCIBOKB_1	764586	763105	SPD_0310	0.0	UPF0371 protein SPD_0310	93.52	100.00	ABJ54480
HPCIBOKB_1	1612558	1611590	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
HPCIBOKB_1	929488	931734	metE	0.0	methionine biosynthesis enzymes	92.79	100.00	AAK74738
HPCIBOKB_1	2140203	2139232	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
HPCIBOKB_1	1360005	1358275	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
HPCIBOKB_1	485768	486916	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.82	99.48	AAL00050
HPCIBOKB_1	13626	15104	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
HPCIBOKB_1	1520858	1519557	Eno	0.0	enolase	86.44	99.77	ABP90468
HPCIBOKB_1	28977	30869	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
HPCIBOKB_1	934652	932943	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
HPCIBOKB_1	2103778	2102687	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
HPCIBOKB_1	151610	150600	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
HPCIBOKB_1	1058361	1057000	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
HPCIBOKB_1	1535265	1534375	bglB	2.69e-177	putative phospho--glucosidase	87.88	99.66	AAK33487
HPCIBOKB_1	931921	932778	metF	2.84e-170	methionine biosynthesis enzymes	88.46	99.31	AAK74739
HPCIBOKB_1	975443	974493	SP_0676	3.45e-169	transcription facot	81.39	98.45	AAK74821
HPCIBOKB_1	829774	830448	rr01	1.08e-126	response regulator	84.89	100.00	CAB54566
HPCIBOKB_1	1201610	1200906	covR	9.65e-126	responder protein	85.53	100.00	AAK71319
HPCIBOKB_1	938618	939289	ciaR	2.07e-124	two component system response regulator	86.16	99.12	AIK75708
HPCIBOKB_1	938618	939286	CiaR	3.83e-124	two-component response regulator	87.44	99.55	AAK74935
HPCIBOKB_1	1201610	1200906	walR	2.19e-119	DNA-binding response regulator	82.13	100.00	ANC99504
HPCIBOKB_1	1871436	1870750	CovR	4.73e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
HPCIBOKB_1	2102513	2102118	SpxA2	2.13e-74	transcriptional regulator	91.67	100.00	ERL21461
HPCIBOKB_1	1069830	1070231	SpxA1	6.22e-69	transcriptional regulator	82.84	100.00	ERL19273
HPCIBOKB_1	2043130	2042717	GrpE	3.99e-66	protein grpE	81.16	80.59	ABP89267
HPCIBOKB_1	2026187	2025696	RopE (M5005_Spy_1611)	1.05e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
HPCIBOKB_1	333215	330915	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.97	98.08	MYN69560
HPCIBOKB_1	114895	115914	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451