Genome ID：GCA_046531395.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
4	22	29	36.62

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
PMFFHKDC_1	1359411	1361330	tet(M)	ARO:3000186	tet(M)	99.37	100.00	AB039845.1
PMFFHKDC_1	1357567	1358304	ErmB	ARO:3000375	ErmB	97.96	98.79	AF242872.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
PMFFHKDC_1	1357567	1358304	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	U86375
PMFFHKDC_1	642234	643451	mef(A)	Erythromycin, Azithromycin	99.92	100.00	HG423652
PMFFHKDC_1	1359411	1361330	tet(M)	Doxycycline, Tetracycline, Minocycline	99.74	100.00	X75073
PMFFHKDC_1	643577	645040	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	98.50	100.00	AF227520

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
PMFFHKDC_1	1357570	1358304	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038790.1
PMFFHKDC_1	1359414	1361330	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	EXACTX	100.00	100.00	WP_000691727.1
PMFFHKDC_1	642234	643448	mef(A)	macrolide efflux MFS transporter Mef(A)	BLASTX	98.02	100.00	WP_063853563.1
PMFFHKDC_1	643577	645037	msr(D)	ABC-F type ribosomal protection protein Msr(D)	BLASTX	97.74	100.00	WP_000420317.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
PMFFHKDC_1	969456	970196	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
PMFFHKDC_1	970253	971618	STER_RS05300	0.0	Capsule	Immune modulation	94.58	99.85	WP_011681173
PMFFHKDC_1	1613743	1614594	rfbD	0.0	Capsule	Immune modulation	94.37	100.00	WP_014621820
PMFFHKDC_1	966553	968013	STU_RS14650	0.0	Capsule	Immune modulation	94.18	100.14	WP_011226049
PMFFHKDC_1	966553	968013	STER_RS05320	0.0	Capsule	Immune modulation	94.05	100.00	WP_011681177
PMFFHKDC_1	970253	971620	STU_RS14630	0.0	Capsule	Immune modulation	94.01	100.00	WP_011226045
PMFFHKDC_1	969456	970196	STU_RS14635	0.0	Capsule	Immune modulation	93.79	100.00	WP_011226046
PMFFHKDC_1	1611371	1612642	STU_RS16265	0.0	Capsule	Immune modulation	93.63	99.76	WP_011226331
PMFFHKDC_1	969456	970191	STR_RS05250	0.0	Capsule	Immune modulation	93.61	98.13	WP_011227246
PMFFHKDC_1	966553	968013	STR_RS05265	0.0	Capsule	Immune modulation	93.29	100.14	WP_041827043
PMFFHKDC_1	1604591	1605796	STU_RS16240	0.0	Capsule	Immune modulation	93.28	100.00	WP_011226326
PMFFHKDC_1	1601756	1603540	STU_RS16230	0.0	Capsule	Immune modulation	92.83	99.94	WP_011226325
PMFFHKDC_1	1606589	1607545	STU_RS16250	0.0	Capsule	Immune modulation	92.37	100.00	WP_011226328
PMFFHKDC_1	1605796	1606605	STU_RS16245	0.0	Capsule	Immune modulation	92.35	100.00	WP_002948020
PMFFHKDC_1	968014	968745	STU_RS14645	0.0	Capsule	Immune modulation	92.08	100.00	WP_011226048
PMFFHKDC_1	968014	968745	STER_RS05315	0.0	Capsule	Immune modulation	91.67	100.00	WP_011681176
PMFFHKDC_1	1607542	1608690	STU_RS16255	0.0	Capsule	Immune modulation	91.56	99.91	WP_041828290
PMFFHKDC_1	795419	796012	STR_RS05880	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
PMFFHKDC_1	1603537	1604571	STU_RS16235	0.0	Capsule	Immune modulation	91.30	99.05	WP_002948022
PMFFHKDC_1	795419	796012	STER_RS06030	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
PMFFHKDC_1	795419	796012	STU_RS15260	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
PMFFHKDC_1	968014	968745	STR_RS05260	0.0	Capsule	Immune modulation	91.12	100.00	WP_011227248
PMFFHKDC_1	1077840	1079498	fbp54	0.0	FBPs	Adherence	90.90	99.94	WP_011227179
PMFFHKDC_1	794550	795419	rfbA	0.0	Capsule	Immune modulation	90.69	100.00	WP_011681286
PMFFHKDC_1	36924	37757	cbpD	0.0	Autolysin	Exoenzyme	90.65	99.29	WP_011226733
PMFFHKDC_1	968754	969446	STR_RS05255	0.0	Capsule	Immune modulation	88.63	99.71	WP_011227247
PMFFHKDC_1	968754	969446	STU_RS14640	0.0	Capsule	Immune modulation	88.63	99.71	WP_011226047
PMFFHKDC_1	1922624	1923634	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
PMFFHKDC_1	620863	622166	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
PMFFHKDC_1	968754	969446	STER_RS05310	0.0	Capsule	Immune modulation	86.91	99.71	WP_011681175
PMFFHKDC_1	1213060	1213821	srtA	0.0	Sortase A	Exoenzyme	84.67	99.87	-
PMFFHKDC_1	796215	797261	rfbB	0.0	Capsule	Immune modulation	84.35	99.90	WP_002263087
PMFFHKDC_1	129498	130781	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
PMFFHKDC_1	1216510	1217493	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.04	100.00	AAK75326
PMFFHKDC_1	1204925	1203852	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
PMFFHKDC_1	1796476	1798782	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
PMFFHKDC_1	1347940	1349421	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
PMFFHKDC_1	530246	531214	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
PMFFHKDC_1	1185867	1183621	metE	0.0	methionine biosynthesis enzymes	92.12	100.00	AAK74738
PMFFHKDC_1	22497	23468	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
PMFFHKDC_1	769161	770891	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
PMFFHKDC_1	1655125	1653974	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
PMFFHKDC_1	1626531	1624543	uvrB	0.0	excinuclease ABC, B subunit	89.29	100.00	AE014259_2
PMFFHKDC_1	2134787	2133309	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
PMFFHKDC_1	620863	622164	Eno	0.0	enolase	86.44	99.77	ABP90468
PMFFHKDC_1	2119428	2117536	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
PMFFHKDC_1	1180702	1182411	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
PMFFHKDC_1	57897	58988	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
PMFFHKDC_1	1977467	1978477	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
PMFFHKDC_1	1062284	1063645	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
PMFFHKDC_1	606444	607334	bglB	1.23e-176	putative phospho--glucosidase	87.54	99.66	AAK33487
PMFFHKDC_1	1141398	1142348	SP_0676	2.66e-169	transcription facot	81.39	98.45	AAK74821
PMFFHKDC_1	1183434	1182577	metF	5.42e-168	methionine biosynthesis enzymes	87.76	99.31	AAK74739
PMFFHKDC_1	1292913	1292242	rr01	4.52e-126	response regulator	84.82	99.56	CAB54566
PMFFHKDC_1	921764	922468	covR	9.58e-126	responder protein	85.53	100.00	AAK71319
PMFFHKDC_1	1176734	1176063	ciaR	2.06e-124	two component system response regulator	86.16	99.12	AIK75708
PMFFHKDC_1	1176734	1176066	CiaR	3.81e-124	two-component response regulator	87.44	99.55	AAK74935
PMFFHKDC_1	921764	922468	walR	2.18e-119	DNA-binding response regulator	82.13	100.00	ANC99504
PMFFHKDC_1	288667	289353	CovR	4.70e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
PMFFHKDC_1	59162	59557	SpxA2	2.12e-74	transcriptional regulator	91.67	100.00	ERL21461
PMFFHKDC_1	1050818	1050417	SpxA1	4.40e-69	transcriptional regulator	82.84	100.00	ERL19273
PMFFHKDC_1	115879	116292	GrpE	1.67e-66	protein grpE	81.88	80.59	ABP89267
PMFFHKDC_1	130948	131439	RopE (M5005_Spy_1611)	1.04e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
PMFFHKDC_1	1796476	1798776	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
PMFFHKDC_1	2013886	2012867	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451