Genome ID：GCA_046531505.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
4	22	29	36.62

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
NHKNCPHF_1	790137	790874	ErmB	ARO:3000375	ErmB	97.96	98.79	AF242872.1
NHKNCPHF_1	787111	789030	tet(M)	ARO:3000186	tet(M)	99.37	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
NHKNCPHF_1	790137	790874	erm(B)	Erythromycin, Lincomycin, Clindamycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	U86375
NHKNCPHF_1	1504935	1506152	mef(A)	Erythromycin, Azithromycin	99.92	100.00	HG423652
NHKNCPHF_1	787111	789030	tet(M)	Doxycycline, Tetracycline, Minocycline	99.74	100.00	X75073
NHKNCPHF_1	1503346	1504809	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	98.50	100.00	AF227520

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
NHKNCPHF_1	790137	790871	erm(B)	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	EXACTX	100.00	100.00	WP_001038790.1
NHKNCPHF_1	787111	789027	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	EXACTX	100.00	100.00	WP_000691727.1
NHKNCPHF_1	1504938	1506152	mef(A)	macrolide efflux MFS transporter Mef(A)	BLASTX	98.02	100.00	WP_063853563.1
NHKNCPHF_1	1503349	1504809	msr(D)	ABC-F type ribosomal protection protein Msr(D)	BLASTX	97.74	100.00	WP_000420317.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NHKNCPHF_1	1178190	1178930	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
NHKNCPHF_1	1176768	1178133	STER_RS05300	0.0	Capsule	Immune modulation	94.58	99.85	WP_011681173
NHKNCPHF_1	533845	534696	rfbD	0.0	Capsule	Immune modulation	94.37	100.00	WP_014621820
NHKNCPHF_1	1180373	1181833	STU_RS14650	0.0	Capsule	Immune modulation	94.18	100.14	WP_011226049
NHKNCPHF_1	1180373	1181833	STER_RS05320	0.0	Capsule	Immune modulation	94.05	100.00	WP_011681177
NHKNCPHF_1	1176766	1178133	STU_RS14630	0.0	Capsule	Immune modulation	94.01	100.00	WP_011226045
NHKNCPHF_1	1178190	1178930	STU_RS14635	0.0	Capsule	Immune modulation	93.79	100.00	WP_011226046
NHKNCPHF_1	535797	537068	STU_RS16265	0.0	Capsule	Immune modulation	93.63	99.76	WP_011226331
NHKNCPHF_1	1178195	1178930	STR_RS05250	0.0	Capsule	Immune modulation	93.61	98.13	WP_011227246
NHKNCPHF_1	1180373	1181833	STR_RS05265	0.0	Capsule	Immune modulation	93.29	100.14	WP_041827043
NHKNCPHF_1	542643	543848	STU_RS16240	0.0	Capsule	Immune modulation	93.28	100.00	WP_011226326
NHKNCPHF_1	544899	546683	STU_RS16230	0.0	Capsule	Immune modulation	92.83	99.94	WP_011226325
NHKNCPHF_1	540894	541850	STU_RS16250	0.0	Capsule	Immune modulation	92.37	100.00	WP_011226328
NHKNCPHF_1	541834	542643	STU_RS16245	0.0	Capsule	Immune modulation	92.35	100.00	WP_002948020
NHKNCPHF_1	1179641	1180372	STU_RS14645	0.0	Capsule	Immune modulation	92.08	100.00	WP_011226048
NHKNCPHF_1	1179641	1180372	STER_RS05315	0.0	Capsule	Immune modulation	91.67	100.00	WP_011681176
NHKNCPHF_1	539749	540897	STU_RS16255	0.0	Capsule	Immune modulation	91.56	99.91	WP_041828290
NHKNCPHF_1	1352374	1352967	STR_RS05880	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
NHKNCPHF_1	543868	544902	STU_RS16235	0.0	Capsule	Immune modulation	91.30	99.05	WP_002948022
NHKNCPHF_1	1352374	1352967	STER_RS06030	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
NHKNCPHF_1	1352374	1352967	STU_RS15260	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
NHKNCPHF_1	1179641	1180372	STR_RS05260	0.0	Capsule	Immune modulation	91.12	100.00	WP_011227248
NHKNCPHF_1	1068888	1070546	fbp54	0.0	FBPs	Adherence	90.90	99.94	WP_011227179
NHKNCPHF_1	1352967	1353836	rfbA	0.0	Capsule	Immune modulation	90.69	100.00	WP_011681286
NHKNCPHF_1	2110626	2111459	cbpD	0.0	Autolysin	Exoenzyme	90.65	99.29	WP_011226733
NHKNCPHF_1	1178940	1179632	STR_RS05255	0.0	Capsule	Immune modulation	88.63	99.71	WP_011227247
NHKNCPHF_1	1178940	1179632	STU_RS14640	0.0	Capsule	Immune modulation	88.63	99.71	WP_011226047
NHKNCPHF_1	224794	225804	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.45	99.80	WP_002986042
NHKNCPHF_1	1526218	1527521	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
NHKNCPHF_1	1178940	1179632	STER_RS05310	0.0	Capsule	Immune modulation	86.91	99.71	WP_011681175
NHKNCPHF_1	934615	935376	srtA	0.0	Sortase A	Exoenzyme	84.67	99.87	-
NHKNCPHF_1	1351125	1352171	rfbB	0.0	Capsule	Immune modulation	84.35	99.90	WP_002263087
NHKNCPHF_1	2017603	2018886	tig/ropA	0.0	Trigger factor	Stress survival	80.84	99.61	WP_000107753

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NHKNCPHF_1	931926	930943	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.04	100.00	AAK75326
NHKNCPHF_1	943511	944584	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
NHKNCPHF_1	351952	349646	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
NHKNCPHF_1	800501	799020	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
NHKNCPHF_1	1618138	1617170	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
NHKNCPHF_1	962569	964815	metE	0.0	methionine biosynthesis enzymes	92.12	100.00	AAK74738
NHKNCPHF_1	2125886	2124915	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
NHKNCPHF_1	1379225	1377495	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
NHKNCPHF_1	493309	494460	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
NHKNCPHF_1	521908	523896	uvrB	0.0	excinuclease ABC, B subunit	89.29	100.00	AE014259_2
NHKNCPHF_1	13636	15114	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
NHKNCPHF_1	1527521	1526220	Eno	0.0	enolase	86.44	99.77	ABP90468
NHKNCPHF_1	28995	30887	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
NHKNCPHF_1	967734	966025	PGM	0.0	phosphoglucomutase	85.11	99.65	ACH87041
NHKNCPHF_1	2090486	2089395	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
NHKNCPHF_1	170954	169944	pdh	0.0	pyruvate dehydrogenase	83.09	99.70	ABP91006
NHKNCPHF_1	1086102	1084741	mnmE	0.0	central tRNA-modifying GTPase	82.24	99.56	ABP90420
NHKNCPHF_1	1541940	1541050	bglB	1.23e-176	putative phospho--glucosidase	87.54	99.66	AAK33487
NHKNCPHF_1	1007038	1006088	SP_0676	2.66e-169	transcription facot	81.39	98.45	AAK74821
NHKNCPHF_1	965002	965859	metF	5.42e-168	methionine biosynthesis enzymes	87.76	99.31	AAK74739
NHKNCPHF_1	855528	856199	rr01	4.52e-126	response regulator	84.82	99.56	CAB54566
NHKNCPHF_1	1226622	1225918	covR	9.58e-126	responder protein	85.53	100.00	AAK71319
NHKNCPHF_1	971702	972373	ciaR	2.06e-124	two component system response regulator	86.16	99.12	AIK75708
NHKNCPHF_1	971702	972370	CiaR	3.81e-124	two-component response regulator	87.44	99.55	AAK74935
NHKNCPHF_1	1226622	1225918	walR	2.18e-119	DNA-binding response regulator	82.13	100.00	ANC99504
NHKNCPHF_1	1859716	1859030	CovR	4.70e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
NHKNCPHF_1	2089221	2088826	SpxA2	2.12e-74	transcriptional regulator	91.67	100.00	ERL21461
NHKNCPHF_1	1097568	1097969	SpxA1	4.40e-69	transcriptional regulator	82.84	100.00	ERL19273
NHKNCPHF_1	2032504	2032091	GrpE	1.67e-66	protein grpE	81.88	80.59	ABP89267
NHKNCPHF_1	2017436	2016945	RopE (M5005_Spy_1611)	1.04e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
NHKNCPHF_1	351952	349652	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
NHKNCPHF_1	134536	135555	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451