Genome ID：GCA_046531515.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	28	34.47

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
NPFOOHKB_1	1506454	1507671	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
NPFOOHKB_1	1504871	1506334	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
NPFOOHKB_1	1506457	1507671	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
NPFOOHKB_1	1504874	1506334	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NPFOOHKB_1	544927	545642	STER_RS07085	0.0	Capsule	Immune modulation	96.51	99.86	WP_011681442
NPFOOHKB_1	540767	541618	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
NPFOOHKB_1	1176353	1177093	STER_RS05305	0.0	Capsule	Immune modulation	94.87	100.00	WP_011681174
NPFOOHKB_1	543957	544925	STER_RS07090	0.0	Capsule	Immune modulation	94.84	100.00	WP_011681443
NPFOOHKB_1	1176353	1177093	STU_RS14635	0.0	Capsule	Immune modulation	94.33	100.00	WP_011226046
NPFOOHKB_1	1174929	1176296	STU_RS14630	0.0	Capsule	Immune modulation	94.30	100.00	WP_011226045
NPFOOHKB_1	1174931	1176296	STER_RS05300	0.0	Capsule	Immune modulation	94.22	99.85	WP_011681173
NPFOOHKB_1	1176358	1177093	STR_RS05250	0.0	Capsule	Immune modulation	93.89	98.13	WP_011227246
NPFOOHKB_1	1178536	1179996	STU_RS14650	0.0	Capsule	Immune modulation	93.84	100.14	WP_011226049
NPFOOHKB_1	1178536	1179996	STER_RS05320	0.0	Capsule	Immune modulation	93.84	100.00	WP_011681177
NPFOOHKB_1	1178536	1179996	STR_RS05265	0.0	Capsule	Immune modulation	93.09	100.14	WP_041827043
NPFOOHKB_1	545988	546764	STER_RS07075	0.0	Capsule	Immune modulation	92.66	100.00	WP_011681440
NPFOOHKB_1	541737	542990	STER_RS07100	0.0	Capsule	Immune modulation	92.34	99.44	WP_011681445
NPFOOHKB_1	2133780	2134619	cbpD	0.0	Autolysin	Exoenzyme	91.91	100.00	WP_011226733
NPFOOHKB_1	1177804	1178535	STU_RS14645	0.0	Capsule	Immune modulation	91.67	100.00	WP_011226048
NPFOOHKB_1	1351364	1351957	STR_RS05880	0.0	Capsule	Immune modulation	91.41	100.00	WP_011226149
NPFOOHKB_1	1177804	1178535	STER_RS05315	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681176
NPFOOHKB_1	1351364	1351957	STER_RS06030	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
NPFOOHKB_1	1351364	1351957	STU_RS15260	0.0	Capsule	Immune modulation	91.25	100.00	WP_011226149
NPFOOHKB_1	1177804	1178535	STR_RS05260	0.0	Capsule	Immune modulation	90.71	100.00	WP_011227248
NPFOOHKB_1	1062359	1064017	fbp54	0.0	FBPs	Adherence	90.66	99.94	WP_011227179
NPFOOHKB_1	1351957	1352826	rfbA	0.0	Capsule	Immune modulation	90.46	100.00	WP_011681286
NPFOOHKB_1	1177103	1177795	STR_RS05255	0.0	Capsule	Immune modulation	88.62	99.86	WP_011227247
NPFOOHKB_1	1177103	1177795	STU_RS14640	0.0	Capsule	Immune modulation	88.62	99.86	WP_011226047
NPFOOHKB_1	1535511	1536814	eno	0.0	Streptococcal enolase	Exoenzyme	88.17	99.54	WP_000022832
NPFOOHKB_1	1177103	1177795	STER_RS05310	0.0	Capsule	Immune modulation	87.46	99.86	WP_011681175
NPFOOHKB_1	230978	231988	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	87.36	99.80	WP_002986042
NPFOOHKB_1	1350047	1351093	rfbB	0.0	Capsule	Immune modulation	83.98	99.81	WP_002263087
NPFOOHKB_1	916671	917432	srtA	0.0	Sortase A	Exoenzyme	83.88	99.87	-
NPFOOHKB_1	2045343	2046626	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753
NPFOOHKB_1	1165271	1165854	SPD_RS01775	1.28e-146	Capsule	Immune modulation	83.08	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NPFOOHKB_1	913982	913008	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	96.31	99.09	AAK75326
NPFOOHKB_1	925565	926638	MntE	0.0	manganese homeostasis	95.81	99.72	ABF32167
NPFOOHKB_1	353250	350944	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
NPFOOHKB_1	771268	769787	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
NPFOOHKB_1	945106	947352	metE	0.0	methionine biosynthesis enzymes	93.19	100.00	AAK74738
NPFOOHKB_1	1628082	1627114	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
NPFOOHKB_1	2149711	2148740	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.36	100.00	ABF36968
NPFOOHKB_1	1378205	1376475	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
NPFOOHKB_1	490472	491623	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
NPFOOHKB_1	527338	529326	uvrB	0.0	excinuclease ABC, B subunit	89.44	100.00	AE014259_2
NPFOOHKB_1	13634	15112	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
NPFOOHKB_1	1536814	1535513	Eno	0.0	enolase	86.44	99.77	ABP90468
NPFOOHKB_1	28981	30873	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.42	98.90	ABP91129
NPFOOHKB_1	2112069	2110978	recA	0.0	DNA recombination and repair	84.37	95.36	AAL00560
NPFOOHKB_1	177142	176132	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
NPFOOHKB_1	1084048	1082687	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
NPFOOHKB_1	1551232	1550342	bglB	2.70e-177	putative phospho--glucosidase	87.88	99.66	AAK33487
NPFOOHKB_1	989597	988647	SP_0676	6.49e-169	transcription facot	81.39	98.45	AAK74821
NPFOOHKB_1	947542	948399	metF	9.42e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
NPFOOHKB_1	831028	831699	rr01	4.66e-126	response regulator	84.82	99.56	CAB54566
NPFOOHKB_1	1225680	1224976	covR	9.69e-126	responder protein	85.53	100.00	AAK71319
NPFOOHKB_1	954240	954911	ciaR	2.08e-124	two component system response regulator	86.16	99.12	AIK75708
NPFOOHKB_1	954240	954908	CiaR	3.85e-124	two-component response regulator	87.44	99.55	AAK74935
NPFOOHKB_1	1225680	1224976	walR	2.20e-119	DNA-binding response regulator	82.13	100.00	ANC99504
NPFOOHKB_1	1880015	1879329	CovR	4.75e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
NPFOOHKB_1	2110805	2110410	SpxA2	2.14e-74	transcriptional regulator	91.67	100.00	ERL21461
NPFOOHKB_1	1095513	1095914	SpxA1	7.66e-69	transcriptional regulator	82.09	100.00	ERL19273
NPFOOHKB_1	2060689	2060276	GrpE	1.69e-66	protein grpE	81.88	80.59	ABP89267
NPFOOHKB_1	2045176	2044685	RopE (M5005_Spy_1611)	1.05e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
NPFOOHKB_1	353250	350950	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.09	98.08	MYN69560
NPFOOHKB_1	140454	141473	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451