Genome ID：GCA_046531535.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
3	17	30	34.61

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
ANELEHPL_1	427629	429548	tet(M)	ARO:3000186	tet(M)	90.77	100.00	AB039845.1

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
ANELEHPL_1	1202042	1203259	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
ANELEHPL_1	1200459	1201922	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302
ANELEHPL_1	427629	429547	tet(M)	Doxycycline, Tetracycline, Minocycline	95.15	99.95	JN846696

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
ANELEHPL_1	1202045	1203259	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
ANELEHPL_1	1200462	1201922	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1
ANELEHPL_1	427629	429545	tet(M)	tetracycline resistance ribosomal protection protein Tet(M)	BLASTX	98.28	100.00	WP_011860841.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
ANELEHPL_1	585893	586744	rfbD	0.0	Capsule	Immune modulation	95.07	100.00	WP_014621820
ANELEHPL_1	1278664	1279395	STER_RS05315	0.0	Capsule	Immune modulation	94.81	100.00	WP_011681176
ANELEHPL_1	589168	589883	STER_RS07085	0.0	Capsule	Immune modulation	94.55	99.86	WP_011681442
ANELEHPL_1	1278664	1279395	STU_RS14645	0.0	Capsule	Immune modulation	94.54	100.00	WP_011226048
ANELEHPL_1	1278664	1279395	STR_RS05260	0.0	Capsule	Immune modulation	94.13	100.00	WP_011227248
ANELEHPL_1	590229	590999	STER_RS07075	0.0	Capsule	Immune modulation	92.48	99.23	WP_011681440
ANELEHPL_1	586863	588121	STER_RS07100	0.0	Capsule	Immune modulation	92.22	99.92	WP_011681445
ANELEHPL_1	1424975	1425568	STR_RS05880	0.0	Capsule	Immune modulation	91.08	100.00	WP_011226149
ANELEHPL_1	1279396	1280856	STER_RS05320	0.0	Capsule	Immune modulation	90.92	99.86	WP_011681177
ANELEHPL_1	1424975	1425568	STER_RS06030	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
ANELEHPL_1	1424975	1425568	STU_RS15260	0.0	Capsule	Immune modulation	90.91	100.00	WP_011226149
ANELEHPL_1	1279396	1280856	STU_RS14650	0.0	Capsule	Immune modulation	90.78	100.00	WP_011226049
ANELEHPL_1	1146284	1147941	fbp54	0.0	FBPs	Adherence	90.36	99.88	WP_011227179
ANELEHPL_1	1279396	1280856	STR_RS05265	0.0	Capsule	Immune modulation	89.97	100.00	WP_041827043
ANELEHPL_1	1277963	1278655	STU_RS14640	0.0	Capsule	Immune modulation	89.90	100.00	WP_011226047
ANELEHPL_1	1277963	1278655	STR_RS05255	0.0	Capsule	Immune modulation	89.61	100.00	WP_011227247
ANELEHPL_1	1277963	1278655	STER_RS05310	0.0	Capsule	Immune modulation	89.47	100.00	WP_011681175
ANELEHPL_1	1597244	1598547	eno	0.0	Streptococcal enolase	Exoenzyme	88.24	99.54	WP_000022832
ANELEHPL_1	414490	415329	cbpD	0.0	Autolysin	Exoenzyme	87.87	99.88	WP_011226733
ANELEHPL_1	984740	985501	srtA	0.0	Sortase A	Exoenzyme	86.65	99.74	-
ANELEHPL_1	2036224	2037237	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	85.67	99.90	WP_002986042
ANELEHPL_1	1423663	1424709	rfbB	0.0	Capsule	Immune modulation	80.99	100.00	WP_009659423
ANELEHPL_1	127438	128721	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753
ANELEHPL_1	1425568	1426437	rfbA	0.0	Capsule	Immune modulation	80.28	99.77	WP_002904719
ANELEHPL_1	1277283	1277953	STU_RS14635	1.33e-146	Capsule	Immune modulation	80.98	90.28	WP_011226046
ANELEHPL_1	1277283	1277953	STER_RS05305	6.17e-145	Capsule	Immune modulation	80.83	90.28	WP_011681174
ANELEHPL_1	1277351	1277953	STR_RS05250	6.26e-135	Capsule	Immune modulation	81.46	80.13	WP_011227246

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
ANELEHPL_1	993633	994706	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
ANELEHPL_1	982053	981079	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	95.69	99.09	AAK75326
ANELEHPL_1	1905108	1907414	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.41	99.22	AAK74619
ANELEHPL_1	846233	844752	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
ANELEHPL_1	1689518	1688550	spr0084	0.0	pathogenitcity related	93.19	98.48	AAK98888
ANELEHPL_1	1013174	1015420	metE	0.0	methionine biosynthesis enzymes	92.92	100.00	AAK74738
ANELEHPL_1	22182	23153	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
ANELEHPL_1	928098	934571	PrtA	0.0	serine protease	91.44	100.61	ABJ55268
ANELEHPL_1	1452985	1451255	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
ANELEHPL_1	570761	572749	uvrB	0.0	excinuclease ABC, B subunit	89.74	100.00	AE014259_2
ANELEHPL_1	1767952	1766801	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
ANELEHPL_1	2232106	2230628	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.83	100.00	ADE32434
ANELEHPL_1	1598547	1597246	Eno	0.0	enolase	86.44	99.77	ABP90468
ANELEHPL_1	2214701	2212809	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.58	98.90	ABP91129
ANELEHPL_1	1018338	1016629	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
ANELEHPL_1	57824	58915	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
ANELEHPL_1	2089478	2090488	pdh	0.0	pyruvate dehydrogenase	83.38	99.70	ABP91006
ANELEHPL_1	1161702	1160341	mnmE	0.0	central tRNA-modifying GTPase	82.89	99.56	ABP90420
ANELEHPL_1	1612960	1612070	bglB	2.44e-176	putative phospho--glucosidase	87.20	99.66	AAK33487
ANELEHPL_1	1015610	1016467	metF	9.74e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
ANELEHPL_1	1059890	1058952	SP_0676	1.54e-167	transcription facot	81.47	97.20	AAK74821
ANELEHPL_1	1314651	1313947	covR	1.81e-126	responder protein	85.96	100.00	AAK71319
ANELEHPL_1	910118	910789	rr01	4.82e-126	response regulator	84.82	99.56	CAB54566
ANELEHPL_1	1023003	1023674	ciaR	2.83e-124	two component system response regulator	86.16	99.12	AIK75708
ANELEHPL_1	1023003	1023671	CiaR	5.17e-124	two-component response regulator	87.44	99.55	AAK74935
ANELEHPL_1	281777	282463	CovR	1.89e-119	serves to repress GAS virulence factor-encoding genes	82.10	100.00	ACE75886
ANELEHPL_1	1314651	1313947	walR	1.09e-118	DNA-binding response regulator	81.70	100.00	ANC99504
ANELEHPL_1	59833	60228	SpxA2	2.21e-74	transcriptional regulator	91.67	100.00	ERL21461
ANELEHPL_1	1173160	1173561	SpxA1	1.43e-68	transcriptional regulator	82.09	100.00	ERL19273
ANELEHPL_1	108384	108797	GrpE	1.75e-66	protein grpE	81.88	80.59	ABP89267
ANELEHPL_1	128888	129379	RopE (M5005_Spy_1611)	1.09e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
ANELEHPL_1	1905108	1907408	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
ANELEHPL_1	2125885	2124866	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	85.88	100.00	ABJ55451
ANELEHPL_1	1126281	1126820	pnuC	1.27e-91	NAD salvage pathway importer	82.78	66.91	AAK75931