Genome ID：GCA_046531555.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	22	31	38.07

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
NKEEKGIC_1	669607	671070	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	100.00	100.00	AF274302
NKEEKGIC_1	668270	669487	mef(A)	Erythromycin, Azithromycin	99.92	100.00	U83667

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
NKEEKGIC_1	668270	669484	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
NKEEKGIC_1	669607	671067	msr(D)	ABC-F type ribosomal protection protein Msr(D)	EXACTX	100.00	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NKEEKGIC_1	991843	993303	STER_RS05320	0.0	Capsule	Immune modulation	97.40	100.00	WP_011681177
NKEEKGIC_1	991843	993303	STU_RS14650	0.0	Capsule	Immune modulation	96.78	100.21	WP_011226049
NKEEKGIC_1	991843	993303	STR_RS05265	0.0	Capsule	Immune modulation	96.23	100.21	WP_041827043
NKEEKGIC_1	1605343	1606152	STU_RS16245	0.0	Capsule	Immune modulation	95.80	100.00	WP_002948020
NKEEKGIC_1	995543	996908	STER_RS05300	0.0	Capsule	Immune modulation	94.66	99.85	WP_011681173
NKEEKGIC_1	1613277	1614128	rfbD	0.0	Capsule	Immune modulation	94.48	100.00	WP_014621820
NKEEKGIC_1	994746	995486	STER_RS05305	0.0	Capsule	Immune modulation	94.47	100.00	WP_011681174
NKEEKGIC_1	1610905	1612176	STU_RS16265	0.0	Capsule	Immune modulation	94.18	99.76	WP_011226331
NKEEKGIC_1	995543	996910	STU_RS14630	0.0	Capsule	Immune modulation	94.15	100.00	WP_011226045
NKEEKGIC_1	993304	994035	STER_RS05315	0.0	Capsule	Immune modulation	94.13	100.00	WP_011681176
NKEEKGIC_1	124959	126242	tig/ropA	0.0	Trigger factor	Stress survival	94.08	100.00	WP_011225339
NKEEKGIC_1	994746	995486	STU_RS14635	0.0	Capsule	Immune modulation	94.06	100.00	WP_011226046
NKEEKGIC_1	993304	994035	STU_RS14645	0.0	Capsule	Immune modulation	93.99	100.00	WP_011226048
NKEEKGIC_1	819488	820081	STR_RS05880	0.0	Capsule	Immune modulation	93.77	100.00	WP_011226149
NKEEKGIC_1	1601303	1603087	STU_RS16230	0.0	Capsule	Immune modulation	93.62	99.94	WP_011226325
NKEEKGIC_1	819488	820081	STER_RS06030	0.0	Capsule	Immune modulation	93.60	100.00	WP_011226149
NKEEKGIC_1	819488	820081	STU_RS15260	0.0	Capsule	Immune modulation	93.60	100.00	WP_011226149
NKEEKGIC_1	994746	995481	STR_RS05250	0.0	Capsule	Immune modulation	93.48	98.13	WP_011227246
NKEEKGIC_1	993304	994035	STR_RS05260	0.0	Capsule	Immune modulation	93.31	100.00	WP_011227248
NKEEKGIC_1	1604138	1605343	STU_RS16240	0.0	Capsule	Immune modulation	92.70	100.00	WP_011226326
NKEEKGIC_1	1606136	1607092	STU_RS16250	0.0	Capsule	Immune modulation	92.69	100.00	WP_011226328
NKEEKGIC_1	1607089	1608237	STU_RS16255	0.0	Capsule	Immune modulation	92.34	100.00	WP_041828290
NKEEKGIC_1	1603084	1604118	STU_RS16235	0.0	Capsule	Immune modulation	91.39	99.05	WP_002948022
NKEEKGIC_1	818619	819488	rfbA	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681286
NKEEKGIC_1	41147	41986	cbpD	0.0	Autolysin	Exoenzyme	90.95	100.00	WP_011226733
NKEEKGIC_1	1101621	1103279	fbp54	0.0	FBPs	Adherence	90.12	99.94	WP_011227179
NKEEKGIC_1	1937730	1938740	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.65	99.80	WP_002986042
NKEEKGIC_1	994044	994736	STR_RS05255	0.0	Capsule	Immune modulation	88.62	99.86	WP_011227247
NKEEKGIC_1	994044	994736	STU_RS14640	0.0	Capsule	Immune modulation	88.62	99.86	WP_011226047
NKEEKGIC_1	647429	648732	eno	0.0	Streptococcal enolase	Exoenzyme	88.32	99.54	WP_000022832
NKEEKGIC_1	994044	994736	STER_RS05310	0.0	Capsule	Immune modulation	87.75	99.86	WP_011681175
NKEEKGIC_1	1254521	1255281	srtA	0.0	Sortase A	Exoenzyme	83.64	99.61	-
NKEEKGIC_1	820285	821331	rfbB	0.0	Capsule	Immune modulation	80.71	100.00	WP_009659423

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NKEEKGIC_1	1246392	1245319	MntE	0.0	manganese homeostasis	96.09	99.72	ABF32167
NKEEKGIC_1	1257969	1258952	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	95.73	100.00	AAK75326
NKEEKGIC_1	1808062	1810368	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.28	99.22	AAK74619
NKEEKGIC_1	1383638	1385119	SPD_0310	0.0	UPF0371 protein SPD_0310	93.32	100.00	ABJ54480
NKEEKGIC_1	556331	557299	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
NKEEKGIC_1	1217588	1215342	metE	0.0	methionine biosynthesis enzymes	92.39	100.00	AAK74738
NKEEKGIC_1	22254	23225	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
NKEEKGIC_1	793241	794971	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	89.95	100.00	AAK34199
NKEEKGIC_1	1627383	1625395	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
NKEEKGIC_1	1657199	1656048	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.58	99.74	AAL00050
NKEEKGIC_1	2124746	2123268	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
NKEEKGIC_1	647429	648730	Eno	0.0	enolase	86.44	99.77	ABP90468
NKEEKGIC_1	2109426	2107534	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.42	98.90	ABP91129
NKEEKGIC_1	1212420	1214129	PGM	0.0	phosphoglucomutase	84.76	99.65	ACH87041
NKEEKGIC_1	61035	62126	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
NKEEKGIC_1	1994136	1995146	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
NKEEKGIC_1	1087856	1089217	mnmE	0.0	central tRNA-modifying GTPase	82.46	99.56	ABP90420
NKEEKGIC_1	633021	633911	bglB	2.66e-177	putative phospho--glucosidase	87.88	99.66	AAK33487
NKEEKGIC_1	1171567	1172505	SP_0676	1.83e-168	transcription facot	81.79	97.20	AAK74821
NKEEKGIC_1	1215152	1214295	metF	9.27e-168	methionine biosynthesis enzymes	87.06	99.31	AAK74739
NKEEKGIC_1	437057	437761	NisK	4.41e-130	two-component signal-transduction systems	91.06	100.00	ABP89872
NKEEKGIC_1	436389	437069	NisR	2.59e-129	two-component signal-transduction systems	93.39	100.00	ABP89873
NKEEKGIC_1	1326684	1326013	rr01	1.52e-125	response regulator	84.38	99.56	CAB54566
NKEEKGIC_1	946343	947047	covR	3.39e-125	responder protein	85.11	100.00	AAK71319
NKEEKGIC_1	1208452	1207781	ciaR	9.55e-124	two component system response regulator	85.71	99.12	AIK75708
NKEEKGIC_1	1208452	1207784	CiaR	1.19e-123	two-component response regulator	87.00	99.55	AAK74935
NKEEKGIC_1	279690	280376	CovR	4.68e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
NKEEKGIC_1	946343	947047	walR	6.22e-119	DNA-binding response regulator	81.70	100.00	ANC99504
NKEEKGIC_1	62302	62697	SpxA2	2.11e-74	transcriptional regulator	91.67	100.00	ERL21461
NKEEKGIC_1	1076387	1075986	SpxA1	4.38e-69	transcriptional regulator	82.84	100.00	ERL19273
NKEEKGIC_1	109771	110184	GrpE	3.94e-66	protein grpE	81.16	80.59	ABP89267
NKEEKGIC_1	126409	126900	RopE (M5005_Spy_1611)	1.04e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
NKEEKGIC_1	1808062	1810362	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	82.97	98.08	MYN69560
NKEEKGIC_1	2032171	2031152	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.35	100.00	ABJ55451