Genome ID：GCA_046531605.1

Potential risk score of uploaded strain

ARGs	VFs	PGs	PPRS
2	20	29	35.28

CARD

Query ID	Begin	End	ARO name	ARO accession	CARD name	Identity	Coverage	Accession no.
No hit found

Resfinder

Query ID	Begin	End	Resistance gene	Phenotype	Identity	Coverage	Accession no.
NHFCAKPK_1	1520125	1521342	mef(A)	Erythromycin, Azithromycin	100.00	100.00	U83667
NHFCAKPK_1	1518477	1519940	msr(D)	Erythromycin, Azithromycin, Telithromycin, Quinupristin, Pristinamycin IA, Virginiamycin S	99.18	100.00	AF274302

AMRFinderPlus

Query ID	Begin	End	Gene symbol	Sequence name	Method	Identity	Coverage	Accession no.
NHFCAKPK_1	1520128	1521342	mef(A)	macrolide efflux MFS transporter Mef(A)	EXACTX	100.00	100.00	WP_000417519.1
NHFCAKPK_1	1518480	1519940	msr(D)	ABC-F type ribosomal protection protein Msr(D)	BLASTX	98.77	100.00	WP_000420313.1

Virulence Factor Database (VFDB)

Query ID	qstart	qend	Gene name	e-value	VF name	VF category	Identity	Coverage	Accession no.
NHFCAKPK_1	529686	530401	STER_RS07085	0.0	Capsule	Immune modulation	96.65	99.86	WP_011681442
NHFCAKPK_1	1179129	1180494	STER_RS05300	0.0	Capsule	Immune modulation	95.46	99.85	WP_011681173
NHFCAKPK_1	1179127	1180494	STU_RS14630	0.0	Capsule	Immune modulation	94.96	100.00	WP_011226045
NHFCAKPK_1	525525	526376	rfbD	0.0	Capsule	Immune modulation	94.95	100.00	WP_014621820
NHFCAKPK_1	528716	529684	STER_RS07090	0.0	Capsule	Immune modulation	94.94	100.00	WP_011681443
NHFCAKPK_1	1182734	1184194	STU_RS14650	0.0	Capsule	Immune modulation	94.25	100.14	WP_011226049
NHFCAKPK_1	1180551	1181291	STER_RS05305	0.0	Capsule	Immune modulation	94.20	100.00	WP_011681174
NHFCAKPK_1	1182734	1184194	STER_RS05320	0.0	Capsule	Immune modulation	94.11	100.00	WP_011681177
NHFCAKPK_1	1182734	1184194	STR_RS05265	0.0	Capsule	Immune modulation	93.36	100.14	WP_041827043
NHFCAKPK_1	1356466	1357059	STR_RS05880	0.0	Capsule	Immune modulation	93.27	100.00	WP_011226149
NHFCAKPK_1	1180551	1181291	STU_RS14635	0.0	Capsule	Immune modulation	93.12	100.00	WP_011226046
NHFCAKPK_1	1356466	1357059	STER_RS06030	0.0	Capsule	Immune modulation	93.10	100.00	WP_011226149
NHFCAKPK_1	1356466	1357059	STU_RS15260	0.0	Capsule	Immune modulation	93.10	100.00	WP_011226149
NHFCAKPK_1	1180556	1181291	STR_RS05250	0.0	Capsule	Immune modulation	92.94	98.13	WP_011227246
NHFCAKPK_1	530747	531523	STER_RS07075	0.0	Capsule	Immune modulation	92.66	100.00	WP_011681440
NHFCAKPK_1	526495	527748	STER_RS07100	0.0	Capsule	Immune modulation	92.35	99.52	WP_011681445
NHFCAKPK_1	1182002	1182733	STU_RS14645	0.0	Capsule	Immune modulation	91.53	100.00	WP_011226048
NHFCAKPK_1	1357059	1357928	rfbA	0.0	Capsule	Immune modulation	91.49	100.00	WP_011681286
NHFCAKPK_1	1182002	1182733	STER_RS05315	0.0	Capsule	Immune modulation	91.26	100.00	WP_011681176
NHFCAKPK_1	2141623	2142462	cbpD	0.0	Autolysin	Exoenzyme	91.07	100.00	WP_011226733
NHFCAKPK_1	1069135	1070793	fbp54	0.0	FBPs	Adherence	90.84	99.94	WP_011227179
NHFCAKPK_1	1182002	1182733	STR_RS05260	0.0	Capsule	Immune modulation	90.57	100.00	WP_011227248
NHFCAKPK_1	210888	211898	plr/gapA	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	88.75	99.80	WP_002986042
NHFCAKPK_1	1540884	1542187	eno	0.0	Streptococcal enolase	Exoenzyme	88.47	99.54	WP_000022832
NHFCAKPK_1	1181301	1181993	STR_RS05255	0.0	Capsule	Immune modulation	87.90	99.86	WP_011227247
NHFCAKPK_1	1181301	1181993	STU_RS14640	0.0	Capsule	Immune modulation	87.90	99.86	WP_011226047
NHFCAKPK_1	1181301	1181993	STER_RS05310	0.0	Capsule	Immune modulation	87.61	99.86	WP_011681175
NHFCAKPK_1	918439	919200	srtA	0.0	Sortase A	Exoenzyme	84.16	99.74	-
NHFCAKPK_1	2044905	2046188	tig/ropA	0.0	Trigger factor	Stress survival	80.68	99.61	WP_000107753
NHFCAKPK_1	1355217	1356263	rfbB	0.0	Capsule	Immune modulation	80.36	99.90	WP_009659423
NHFCAKPK_1	1169450	1170033	SPD_RS01775	5.90e-155	Capsule	Immune modulation	83.93	96.20	WP_001819836

VirulenceFinder

Query ID	Begin	End	Database	Virulence factor	Protein function	Identity	Coverage	Accession no.
No hit found

PHI-base

Query ID	qstart	qend	Gene name	e-value	Function	Identity	Coverage	Gene ID
NHFCAKPK_1	915751	914777	ldh(Sp_1220)	0.0	L-lactate dehydrogenase	95.69	99.09	AAK75326
NHFCAKPK_1	928397	929470	MntE	0.0	manganese homeostasis	95.53	99.72	ABF32167
NHFCAKPK_1	337964	335658	pfl2(Sp_0459)	0.0	formate acetyltransferase	94.54	99.22	AAK74619
NHFCAKPK_1	763840	762359	SPD_0310	0.0	UPF0371 protein SPD_0310	93.12	100.00	ABJ54480
NHFCAKPK_1	1633258	1632290	spr0084	0.0	pathogenitcity related	92.88	98.48	AAK98888
NHFCAKPK_1	956450	958696	metE	0.0	methionine biosynthesis enzymes	92.52	100.00	AAK74738
NHFCAKPK_1	2156852	2155881	prsA2	0.0	ribose-phosphate pyrophosphokinase	91.67	100.00	ABF36968
NHFCAKPK_1	1383305	1381575	ptsI	0.0	phosphoenolpyruvate-protein phosphotransferase	90.12	100.00	AAK34199
NHFCAKPK_1	511630	513618	uvrB	0.0	excinuclease ABC, B subunit	89.59	100.00	AE014259_2
NHFCAKPK_1	483144	484295	potA	0.0	ABC transporter ATP-binding protein-spermidine/putrescine transport	89.32	99.74	AAL00050
NHFCAKPK_1	13565	15043	IMPDH	0.0	inosine-5'-monophosphate dehydrogenase	87.63	100.00	ADE32434
NHFCAKPK_1	1542187	1540886	Eno	0.0	enolase	86.44	99.77	ABP90468
NHFCAKPK_1	28919	30811	gidA	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	85.26	98.90	ABP91129
NHFCAKPK_1	961616	959907	PGM	0.0	phosphoglucomutase	84.94	99.65	ACH87041
NHFCAKPK_1	2122323	2121232	recA	0.0	DNA recombination and repair	84.64	95.36	AAL00560
NHFCAKPK_1	155492	154482	pdh	0.0	pyruvate dehydrogenase	82.79	99.70	ABP91006
NHFCAKPK_1	1084315	1082954	mnmE	0.0	central tRNA-modifying GTPase	82.67	99.56	ABP90420
NHFCAKPK_1	1557847	1556957	bglB	2.26e-177	putative phospho--glucosidase	87.88	99.66	AAK33487
NHFCAKPK_1	958883	959740	metF	9.84e-169	methionine biosynthesis enzymes	88.11	99.31	AAK74739
NHFCAKPK_1	1002477	1001527	SP_0676	5.41e-168	transcription facot	81.07	98.45	AAK74821
NHFCAKPK_1	843731	844402	rr01	3.03e-126	response regulator	84.82	99.56	CAB54566
NHFCAKPK_1	1229682	1228978	covR	3.45e-125	responder protein	85.11	100.00	AAK71319
NHFCAKPK_1	965583	966254	ciaR	7.00e-124	two component system response regulator	86.16	99.12	AIK75708
NHFCAKPK_1	965583	966251	CiaR	9.78e-124	two-component response regulator	87.00	99.55	AAK74935
NHFCAKPK_1	1890274	1889588	CovR	4.77e-119	serves to repress GAS virulence factor-encoding genes	81.66	100.00	ACE75886
NHFCAKPK_1	1229682	1228978	walR	6.34e-119	DNA-binding response regulator	81.70	100.00	ANC99504
NHFCAKPK_1	2121058	2120663	SpxA2	2.15e-74	transcriptional regulator	91.67	100.00	ERL21461
NHFCAKPK_1	1095784	1096185	SpxA1	4.47e-69	transcriptional regulator	82.84	100.00	ERL19273
NHFCAKPK_1	2061673	2061260	GrpE	4.01e-66	protein grpE	81.16	80.59	ABP89267
NHFCAKPK_1	2044738	2044247	RopE (M5005_Spy_1611)	2.86e-71	probable DNA-directed RNA polymerase subunit delta	82.93	85.86	AAK34603
NHFCAKPK_1	337964	335664	PFL (B9H01_RS01125)	0.0	formate C-acetyltransferase	83.22	98.08	MYN69560
NHFCAKPK_1	118790	119809	ilvC (SPD_0406)	0.0	ketol-acid reductoisomerase (NADP(+))	97.06	100.00	ABJ55451